MicroRNAs Regulating Oxidative Stress in Human Fertility: A Narrative Review of Mechanistic Insights and Clinical Potential [0.03%]
微小核糖核酸调节氧化应激与人类生育：机制见解和临床应用的叙述性综述
Ioanna Vassilaki,Anastasios Potiris,Ekaterini Domali et al.
Ioanna Vassilaki et al.
Human infertility represents a multifaceted condition, with oxidative stress (OS) and microRNAs (miRNAs) emerging as key contributors to its pathophysiology. This comprehensive review explores the complex interplay between reactive oxygen s...
Temporal Trends in Cardiovascular Health Metrics in Italy, 2015-2024: A Ten-Year Report from the Longevity Check-Up (Lookup) 8+ Study [0.03%]
意大利2015-2024年心血管健康指标的 temporal trends：来自长寿检查计划（Longevity Check-Up，简称LOOKUP）8+研究的十年报告
Stefano Cacciatore,Elena Levati,Riccardo Calvani et al.
Stefano Cacciatore et al.
Background/objectives: The objective of this ten-year report is to describe temporal trends in the cardiovascular health (CVH) score and its individual components across ages and sexes. We also examined the impact of the ...
Elevated NIS Expression Correlates with Chemoresistance in Triple-Negative Breast Cancer: Potential Link to FOXA1 Activity [0.03%]
三阴性乳腺癌中NIS高表达与化疗耐药的相关性：可能与FOXA1活性有关
Grigory Demyashkin,Anastasia Guzik,Mikhail Parshenkov et al.
Grigory Demyashkin et al.
Background: Sodium/iodide symporter (NIS) is a membrane protein involved in iodide transport into cells, making it a key component of thyroid physiology and radioiodine therapy for thyroid cancer. Although NIS is expresse...
Association Between Peritoneal Dialysis-Associated Peritonitis and the Risk of All-Cause Mortality and Cardiovascular Death: A Time-Matched Retrospective Cohort Study [0.03%]
腹膜透析相关性腹膜炎与全因死亡率及心血管疾病死亡风险关联的病例对照研究
Surapon Nochaiwong,Kajohnsak Noppakun,Manish M Sood et al.
Surapon Nochaiwong et al.
Background/Objectives: Although peritoneal dialysis (PD) practices have improved over the past decades, limited evidence exists on all-cause mortality and cardiovascular death following PD-associated peritonitis. This study aimed to investi...
Multicenter Study
Medical sciences (Basel, Switzerland). 2025 Oct 30;13(4):249. DOI:10.3390/medsci13040249 2025
Identification and Computational Analysis of BRCA2 Variants in Mexican Women from Jalisco, Mexico, with Breast and Ovarian Cancer [0.03%]
墨西哥哈利斯科州乳腺癌和卵巢癌女性BRCA2变异的鉴定与计算分析
Patricia Montserrat García-Verdín,José Elías García-Ortiz,Asbiel Felipe Garibaldi-Ríos et al.
Patricia Montserrat García-Verdín et al.
Background: Breast and ovarian cancers (BC and OC) are prevalent malignancies in women globally, with germline variants in the BRCA2 gene significantly increasing the risk of developing these cancers. Despite extensive st...
A Prospective Cohort Study Comparing Microscopy and Culture in the Diagnosis of Superficial Fungal Skin Infections [0.03%]
一项关于表浅皮肤真菌病诊断中显微镜检查与培养对比的前瞻性队列研究
Amelia Yuting Monteiro,Hui Mei Cheng,Larissa Lim et al.
Amelia Yuting Monteiro et al.
Superficial fungal skin infections are common but often misdiagnosed, which may result in inappropriate treatment and the worsening of symptoms. An accurate and timely diagnosis is essential to differentiate these infections from similar co...
Comparative Study
Medical sciences (Basel, Switzerland). 2025 Oct 29;13(4):247. DOI:10.3390/medsci13040247 2025
Nuclear CaMKII Isoforms as Regulators of Transcription: From Developmental to Pathological Persistence [0.03%]
核钙调神经磷酸酶II同工酶作为转录调控因子：从发育到病理持续存在
Areli Marlene Gaytán-Gómez,Claudio Adrián Ramos-Cortés,Ricardo Xopan Suarez-García et al.
Areli Marlene Gaytán-Gómez et al.
Calcium/calmodulin-dependent protein kinase II (CaMKII) comprises multiple isoforms with distinct nuclear variants that exert transcriptional control in a context-dependent manner. Among them, CaMKIIδB and δ9 in the heart, and CaMKIIγ in...
Multimodal Imaging of Ductal Carcinoma In Situ: A Single-Center Study of 75 Cases [0.03%]
导管原位癌的多模态影像研究：单中心75例分析
Fabrizio Urraro,Nicoletta Giordano,Vittorio Patanè et al.
Fabrizio Urraro et al.
Introduction: Ductal carcinoma in situ (DCIS) is a non-invasive precursor of breast cancer, usually detected on mammography as clustered microcalcifications. Many cases, however, lack calcifications and require complementary imaging. This s...
Derivation of a Simple Risk Scoring Scheme for Prediction of Severe Dengue Infection in Adult Patients in Thailand [0.03%]
泰国成人登革热严重感染的风险预测及评分系统的衍生研究
Surangrat Pongpan,Patcharin Khamnuan,Pantitcha Thanatrakolsri et al.
Surangrat Pongpan et al.
Background/objectives: Severe dengue infection remains a major public health burden in Thailand, where timely identification of high-risk patients is essential for effective clinical management. Existing predictive models...
Identifying Cardio-Metabolic Subtypes of Prediabetes Using Latent Class Analysis [0.03%]
使用潜在类分析识别糖尿病前期的心脏代谢亚型
Gulnaz Nuskabayeva,Yerbolat Saruarov,Karlygash Sadykova et al.
Gulnaz Nuskabayeva et al.
Background/Objectives: Prediabetes (PreDM) is a heterogeneous condition, impacting hundreds of millions worldwide, associated with a substantially high risk of Type 2 Diabetes Mellitus (T2DM) and cardiovascular complications. Early identifi...