Obesogenic Dysregulation of Human Periprostatic Adipose Tissue Promotes the Viability of Prostate Cells and Reduces Their Sensitivity to Docetaxel and Cabazitaxel [0.03%]
人前列腺周围脂肪组织的致肥胖失调促进前列腺细胞存活并降低其对多西他赛和卡巴他赛的敏感性
Mariana Feijó,Lara R S Fonseca,Gonçalo Catarro et al.
Mariana Feijó et al.
Background: Periprostatic adipose tissue (PPAT) has been shown to play a significant role in prostate cancer (PCa) development and progression. This relationship is further exacerbated by obesity, as PPAT-secreted factors...
Empowering Patients: A Multicomponent Workshop Improves Self-Management and Quality of Life in Chronic Pain [0.03%]
赋能患者：多管齐下的工作坊可改善慢性疼痛患者的自我管理能力和生活质量
María Victoria Ruiz-Romero,María Begoña Gómez-Hernández,Ana Porrúa-Del Saz et al.
María Victoria Ruiz-Romero et al.
Background: Chronic pain is a prevalent and disabling condition, affecting 20-30% of the global population, which requires multidisciplinary approaches integrating non-pharmacological therapies and promoting patient engag...
Why and How Are Infants with Hutchinson-Gilford Progeria Syndrome Born Without Severe Manifestations? [0.03%]
为什么及如何 Hutchinson-Gilford 前科氏综合征婴儿出生时没有严重症状？
Mariia A Erokhina,Ekaterina A Vorotelyak,Andrey V Vasiliev et al.
Mariia A Erokhina et al.
Children with Hutchinson-Gilford progeria syndrome (HGPS) are born without height and weight abnormalities, and postnatal development is delayed from two months of age. The pathophysiological manifestations of HGPS can be categorized into t...
Is a Single Lipoprotein(a) Measurement Once in a Lifetime Sufficient? The Results from the STAR-Lp(a) Study [0.03%]
生命周期一次脂蛋白(a)检测结果足够吗？STAR-Lp(a)研究结果
Monika Burzyńska,Piotr Jankowski,Maciej Banach et al.
Monika Burzyńska et al.
Background: Guidelines suggest that a single lifetime measurement of lipoproteina(a) [Lp(a)] is sufficient for most patients as its levels are largely genetically determined and do not significantly change over time. The aim of the study wa...
Effect of N-Acetyl-L-Cysteine (NAC) on Inflammation After Intraperitoneal Mesh Placement in an Escherichia coli Septic Rat Model: A Randomized Experimental Study [0.03%]
N-乙酰半胱氨酸(NAC)对腹腔镜手术后的大肠杆菌感染鼠模型腹膜炎的影响：一项随机实验研究
Styliani Parpoudi,Ioannis Mantzoros,Orestis Ioannidis et al.
Styliani Parpoudi et al.
Background/Objectives: The safety of intraperitoneal mesh placement in contaminated fields remains controversial because of the increased risk of inflammation and adhesion formation. N-acetyl-L-cysteine (NAC) has antioxidant, pro-fibrinolyt...
Ethical Horizons in Robotic Rehabilitation: Ensuring Safe AI Use Under the EU AI Act [0.03%]
机器人康复中的伦理视野：在欧盟《人工智能法案》框架下确保安全使用AI
Rocco Salvatore Calabrò
Rocco Salvatore Calabrò
Artificial intelligence (AI) is reshaping robotic rehabilitation and shifting practice beyond pre-programmed repetitive movement patterns toward data-driven and personalised therapeutic interventions for people with neurological and musculo...
Determinants of Entero-Invasive and Non-Entero-Invasive Diarrheagenic Bacteria Among HIV-Positive and HIV-Negative Adults in Ghana [0.03%]
艾滋病毒阳性和阴性成人感染侵入性和非侵入性致泻细菌的决定因素
Hagen Frickmann,Fred Stephen Sarfo,Betty Roberta Norman et al.
Hagen Frickmann et al.
Objectives: This observational and cross-sectional study investigated differential associations between entero-invasive and non-entero-invasive enteric pathogens and HIV infection, considering socioeconomic, clinical and ...
Observational Study
Medical sciences (Basel, Switzerland). 2025 Dec 12;13(4):316. DOI:10.3390/medsci13040316 2025
Outcome and Toxicity of Moderately Hypofractionated Post-Prostatectomy Radiotherapy: A Retrospective Study [0.03%]
根治性前列腺切除术后中等强度减量分割放疗的疗效及毒副反应的回顾性研究
Rocchina Vilella,Fiorella D&#x;Auria,Luciana Valvano et al.
Rocchina Vilella et al.
Background: In this study, we retrospectively analyzed clinical and toxicity outcomes of 67 prostate cancer (PCa) patients undergoing moderately hypofractionated radiotherapy (RT) after prostatectomy, with adjuvant or salvage intent. Method...
Evaluation of Cell Mimics as Potential Quality Controls for Human Leukocyte Immunophenotyping [0.03%]
细胞模拟物作为人类白细胞免疫表型质量控制的潜力评估
Louis Waeckel,Brigitte Le Mauff,Jacques Trauet et al.
Louis Waeckel et al.
Background. Routine lymphocyte counting requires quality assurance validation using quality controls (QCs) that closely resemble fresh human blood leukocytes. This study aimed to evaluate a novel artificial product designed to mimic leukocy...
Echocardiographic Alterations in Subjects with Sarcopenia and Right Heart Failure [0.03%]
肌少症和右心衰竭患者的超声心动图改变
Arturo Orea-Tejeda,Luis Aldo Delgado-Pérez,Benigno Valderrábano-Salas et al.
Arturo Orea-Tejeda et al.
Background: Chronic heart failure (HF) is a significant public health issue. The principal risk factors for left ventricular diastolic dysfunction (LVDD) include older age, female sex, obesity, hypertension, smoking, and ...