Prognostic Value of Serial Lactate Measurement in Pediatric Cardiac Surgery Patients with Congenital Heart Disease in Southeast Mexico [0.03%]
墨西哥东南部先天性心脏病儿科心脏手术患者连续测量乳酸的预后价值
Ely Sanchez-Felix,Amonario Olivera-Mar,Miguel Santaularia-Tomas et al.
Ely Sanchez-Felix et al.
Background/objectives: Lactate, traditionally considered a byproduct of anaerobic metabolism, is increasingly recognized as a biomarker of tissue perfusion and systemic stress. While hyperlactatemia is frequent after pedi...
Headache Onset Timing as a Predictor for Comorbid Conditions of Pediatric Primary Headache [0.03%]
小儿原发性头痛合并症的发作时间预测因子
Hideki Shimomura,Sachi Tokunaga,Eisuke Terasaki et al.
Hideki Shimomura et al.
Background/Objectives: Pediatric patients with primary headaches frequently exhibit diverse comorbid conditions, often rendering their headaches intractable. Early identification of and intervention for comorbid conditions are crucial for i...
AI in the Hot Seat: Head-to-Head Comparison of Large Language Models and Cardiologists in Emergency Scenarios [0.03%]
紧急情况下的头对头比较：人工智能在热座上的表现是否优于心脏病专家？大型语言模型与 cardiologist 的对比分析
Vedat Cicek,Lili Zhao,Yalcin Tur et al.
Vedat Cicek et al.
Background: The clinical applicability of large language models (LLMs) in high-stakes cardiac emergencies remains unexplored. This study evaluated how well advanced LLMs perform in managing complex catheterization laboratory (Cath lab) scen...
Comparative Study
Medical sciences (Basel, Switzerland). 2026 Jan 8;14(1):33. DOI:10.3390/medsci14010033 2026
Leptin Drives Breast Cancer Aggressiveness Acting Through the Activation of the NCOA1/STAT3 Pathway [0.03%]
脂联素通过激活NCOA1/STAT3信号通路驱动乳腺癌侵袭性
Khouloud Ayed,Amal Gorrab,Hichem Bouguerra et al.
Khouloud Ayed et al.
Background/Objectives: Obesity-associated hyperleptinemia has been linked to breast cancer (BC) progression via mechanisms that remain incompletely understood. This study explores the role of leptin and its receptor (LEPR) in facilitating B...
Longitudinal Study of TCF4 CTG Trinucleotide Repeat Length and Disease Severity in Fuchs' Endothelial Corneal Dystrophy [0.03%]
Fuchs角膜内皮 dystrophy的CTG三核苷酸重复长度及其与疾病严重程度的纵向研究
Jasmin X J Teo,Dawn J H Neo,Jessica Q H Choo et al.
Jasmin X J Teo et al.
Objective: This was a longitudinal study of TCF4 CTG18.1 trinucleotide repeat lengths in 17 patients (27 eyes) diagnosed with Fuchs' endothelial corneal dystrophy (FECD), and it aimed to correlate the repeat expansion status with disease se...
Integrative Sequencing and Proteogenomic Approaches to Intratumoral Heterogeneity in Cholangiocarcinoma: Implications for Precision Diagnosis and Therapy [0.03%]
整合测序和蛋白质基因组方法在肝内胆管癌瘤内异质性中的应用：精准诊断和治疗的启示
Sirinya Sitthirak,Arporn Wangwiwatsin,Apinya Jusakul et al.
Sirinya Sitthirak et al.
Cholangiocarcinoma (CCA) is a highly aggressive cancer of the biliary tract, distinguished by significant intratumoral heterogeneity (ITH), which contributes to therapy resistance and unfavorable clinical outcomes. Traditional genome profil...
Characterizing Differences in Endolymphatic Hydrops Signatures Among Meniere's Disease Patients with and Without Migraine [0.03%]
有偏头痛和无偏头痛的梅尼埃病患者内淋巴囊积水特征的区别
Yoshiyuki Sasano,Fumihiro Mochizuki,Yusuke Ito et al.
Yoshiyuki Sasano et al.
Background/Objectives: Migraine is frequently comorbid with Meniere's disease, which may complicate interpretation of inner ear imaging and clinical diagnosis. While endolymphatic hydrops has been studied in Meniere's disease and vestibular...
The Diagnostic Potential of Eye Tracking to Detect Autism Spectrum Disorder in Children: A Systematic Review [0.03%]
儿童自闭症谱系障碍诊断中眼动检测的应用潜力：一项系统性回顾研究
Marcella Di Cara,Carmela De Domenico,Adriana Piccolo et al.
Marcella Di Cara et al.
Background: Autism spectrum disorder (ASD) is associated with distinct visual attention patterns that provide insight into underlying social-cognitive mechanisms. Methods: This systematic review (PROSPERO: CRD42023429316), conducted per PRI...
Improved Sphincter Muscle Regeneration by Myoblasts from M. extensor carpi radialis in a Large Animal Model of Urinary Incontinence [0.03%]
采用兔尺侧腕长肌卫星细胞修复膀胱出口闭合功能缺陷的研究
Niklas Harland,Lukas Schwarz,Meltem Avci-Adali et al.
Niklas Harland et al.
Purpose: Stress urinary incontinence (SUI) is a significant medical challenge affecting substantial parts of modern societies. Several studies suggested that cell therapy may alleviate the symptoms. However, in many cases, the overall effic...
Short- and Middle-Term Nephroprotective and Cardioprotective Effects of Pentoxifylline in Patients with Diabetic Nephropathy: A Randomized Controlled Trial [0.03%]
培哚普利对糖尿病肾病患者短期及中期的肾脏和心脏保护作用：随机对照试验
Oliva Mejía-Rodríguez,Marcela Ávila-Díaz,Carmen Prado-Uribe et al.
Oliva Mejía-Rodríguez et al.
Background/Objectives. Pentoxifylline (PTF) is an effective treatment to delay the progress of Diabetic Nephropathy; it also has beneficial effects on heart failure, two closely related clinical conditions. However, the simultaneous Nephrop...
Randomized Controlled Trial
Medical sciences (Basel, Switzerland). 2026 Jan 6;14(1):26. DOI:10.3390/medsci14010026 2026