Primary Malignant Tumours of the Proximal Third of the Fibula, from Epidemiology to Treatment: A Systematic Review [0.03%]
腓骨近端三分之一原发性恶性肿瘤：从流行病学到治疗的系统综述
Simone Otera,Virginia Maria Formica,Daphne Sorrentino et al.
Simone Otera et al.
Background: Primary fibula tumours are rare, representing approximately 0.25% of all primary bone tumours. While benign lesions are often asymptomatic, malignant ones typically present with pain and functional impairment. Most tumours arise...
Liver Fibrosis and the Risks of Impaired Cognition and Dementia: Mechanisms, Evidence, and Clinical Implications [0.03%]
肝纤维化与认知损害和痴呆风险：机制、证据及临床意义
Mohamad Jamalinia,Ralf Weiskirchen,Amedeo Lonardo
Mohamad Jamalinia
Liver fibrosis, the progressive accumulation of scar tissue resulting from chronic liver disease, is increasingly recognized as a multi-system condition, the effects of which extend beyond the liver, affecting brain health. Dementia, charac...
Circulating Lipid Peroxides Associate with More Aggressive Tumor Phenotypes and Increased Risks of Recurrence and Mortality in Breast Cancer Patients [0.03%]
循环脂质过氧化物与乳腺癌患者的侵袭性肿瘤表型以及复发和死亡风险增加相关
Julia Fernandes Gois Orrutéa,Rafaela Oliveira Matos,João Paulo Araújo Pinto et al.
Julia Fernandes Gois Orrutéa et al.
Background/Objectives: Breast cancer is the most common neoplasm among women and remains the leading cause of cancer-related mortality in the female population worldwide. Tumor cells exist within a highly oxidative microenvironment, which p...
Application of Medicinal Mushrooms for the Treatment of Peripheral Nerve Injury: A Systematic Review [0.03%]
药用蘑菇治疗周围神经损伤的应用：系统性综述
Nurul Aini Binti Taib,Zolkapli Bin Eshak,Hussin Bin Muhammad et al.
Nurul Aini Binti Taib et al.
Background/Objective: Current treatments for peripheral nerve injury (PNI) lack robust evidence to suggest complete recovery; hence, alternative therapeutics offer new opportunities to develop more effective protocols. Mushroom species and ...
In Silico Investigation Reveals IL-6 as a Key Target of Asiatic Acid in Osteoporosis: Insights from Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulation [0.03%]
基于网络药理学、分子对接和分子动力学模拟的白芍酸在骨质疏松症中靶点的预测及验证研究
Wanatsanan Chulrik,Aman Tedasen,Nateelak Kooltheat et al.
Wanatsanan Chulrik et al.
Background/objectives: Osteoporosis is a multifactorial skeletal disorder in which chronic inflammation, dysregulated cytokine signaling, and metabolic imbalance contribute to excessive bone resorption and impaired bone f...
Timing and Benefit of Early Versus Delayed Reoperation in Recurrent Glioblastoma: A Systematic Review and Meta-Analysis of Survival and Functional Outcomes [0.03%]
复发性胶质母细胞瘤早期再手术与延迟再手术的时机和收益：生存率及功能预后系统评价和meta分析
Tomasz Tykocki,Łukasz Rakasz
Tomasz Tykocki
Background: The prognostic relevance of surgical timing at glioblastoma recurrence remains uncertain, and definitions of early versus delayed reoperation vary widely. Whether earlier surgery provides meaningful survival or functional benefi...
What Is the Role of Diabetic Alert Dogs in Glycemic Monitoring for Individuals with Type 1 Diabetes? A Scoping Review [0.03%]
糖尿病警报犬在1型糖尿病患者血糖监测中的作用是什么？一项范围综述
Nathalia Marçallo Peixoto Souza,Paula Rothbarth Silva,Christiane Mayrhofer Grocoske de Lima et al.
Nathalia Marçallo Peixoto Souza et al.
Background/Objectives: Type 1 diabetes mellitus (T1DM) is a chronic autoimmune condition that requires continuous glycemic monitoring to prevent acute and long-term complications. In recent years, Diabetic Alert Dogs (DADs) have been increa...
Mai Mostafa,Alaa Elhaddad,Mohamed Z Gad et al.
Mai Mostafa et al.
The major subtypes of leukemia show sex differences. This review summarizes current knowledge and identifies gaps regarding sex differences across acute myeloid leukemia, acute lymphoblastic leukemia, chronic myeloid leukemia, and chronic l...
Sexual Health After Neurological Disorders: A Comprehensive Umbrella Review of Treatment Evidence [0.03%]
神经系统疾病后的性健康状况：治疗证据的全面伞式回顾
Alfredo Manuli,Andrea Calderone,Desiree Latella et al.
Alfredo Manuli et al.
Background/Objectives: Sexual dysfunction (SD) and broader sexual health problems are common after neurological disorders, yet interventional evidence is fragmented across conditions and outcomes. This umbrella review mapped and appraised s...
Comparison of Effectiveness Between Providence Nighttime Versus Full-Time Brace in Adolescent Idiopathic Scoliosis: A Narrative Review [0.03%]
青少年特发性脊柱侧凸夜间佩戴和全天佩戴支具的有效性比较：综述型研究
Ana Belén Jiménez-Jiménez,Elena Goicoechea-Rey,Pablo Padial López-Durán et al.
Ana Belén Jiménez-Jiménez et al.
Background/Objectives: Adolescent idiopathic scoliosis (AIS) is a three-dimensional deformity of the spine with multifactorial etiology. Its treatment is conservative and/or surgical. The most commonly used conservative method is a full-tim...