Quantifying the Learning Curve in Ultrasound-Guided Vascular Access: Proficiency Metrics of Self-Taught Axillary Vein Puncture for CIED Implantation [0.03%]
量化超声引导血管通路学习曲线：自学腋静脉穿刺植入心脏植入式电子设备的熟练度指标
Dimitrios A Vrachatis,Konstantinos A Papathanasiou,Ioannis Anagnostopoulos et al.
Dimitrios A Vrachatis et al.
Background: Ultrasound (US)-guided axillary vein puncture (AVP) is an established technique for cardiac implantable electronic device (CIED) implantation. Yet real-world data concerning shifting from conventional venous a...
Clinical and Metabolic Predictors of Response to Focused Extracorporeal Shockwave Therapy in Rotator Cuff Tendinopathy: A Retrospective Cohort Study [0.03%]
跟腱病聚焦冲击波治疗反应的临床和代谢预测因素：回顾性队列研究
Sveva Maria Nusca,Eleonora Latini,Gabriele Santilli et al.
Sveva Maria Nusca et al.
Background: Rotator cuff tendinopathy is a major cause of shoulder pain and disability. Focused extracorporeal shockwave therapy (ESWT) is an established conservative treatment option; however, the predictive factors infl...
Purpose in Life and Estimated Type 2 Diabetes Risk: Cross-Sectional Associations Across Three Validated Risk Scores in 93,077 Spanish Working Adults [0.03%]
人生目的与2型糖尿病风险估计：在93,077名西班牙在职成年人中三种经验证风险评分的横断面相关性分析
Pilar García Pertegaz,Pedro Juan Tárraga López,Irene Coll Campayo et al.
Pilar García Pertegaz et al.
Background: Psychosocial well-being has been increasingly recognized as a relevant factor in cardiometabolic health; however, evidence linking Purpose in Life with type 2 diabetes risk across validated prediction tools remains limited. This...
Biomechanical Voice Parameters as Potential Biomarkers for Phenotype Differentiation in Amyotrophic Lateral Sclerosis: A Cross-Sectional Study [0.03%]
横断面研究：生物力学发声参数作为潜在生物标志物在肌萎缩侧索硬化表型区分中的作用
Margarita Pérez-Bonilla,Marina Mora-Ortiz,Paola Díaz-Borrego et al.
Margarita Pérez-Bonilla et al.
Background/Objectives: Amyotrophic lateral sclerosis (ALS) is a clinically heterogeneous neurodegenerative disease in which bulbar involvement frequently affects speech and voice production. Although acoustic voice analysis can detect phona...
Observational Study
Medical sciences (Basel, Switzerland). 2026 Feb 26;14(1):112. DOI:10.3390/medsci14010112 2026
Immunotherapies for Ischemic Stroke Patients: Current Status and Future Directions [0.03%]
缺血性卒中患者的免疫治疗：现状和未来方向
Riley M McCabe,Lauren Hurley,Kasey Pull et al.
Riley M McCabe et al.
Background/objectives: Ischemic stroke occurs when a thrombus forms within a blood vessel in the brain. This results in reduced levels of oxygen and glucose, leading to the death of cells and a reduction in function. Ther...
Translating Fibrosis to Malignancy: Biomarkers and Therapeutic Opportunities in Liver Fibrosis and Hepatocellular Carcinoma [0.03%]
从肝纤维化到肝细胞癌：生物标志物和治疗机会
Daniel Neureiter,Tobias Kiesslich,Matthias Ocker
Daniel Neureiter
Background/objectives: Hepatocellular carcinoma (HCC) commonly arises from chronic liver diseases that show progressing fibrosis and cirrhosis. The molecular mechanisms driving the transition from advanced fibrosis to ove...
Interventions for Hypertrophic Obstructive Cardiomyopathy: Defining the Gold Standard, Assessing Durability, and Guiding Patient Selection [0.03%]
肥厚型梗阻性心肌病的治疗：确立金标准、评估持久性和指导患者选择
Ajibola Anifowose,Marco Tagliafierro,Ghadeer Mahdi et al.
Ajibola Anifowose et al.
Hypertrophic obstructive cardiomyopathy (HOCM) is a genetic disorder characterized by a dynamic left ventricular outflow tract (LVOT) obstruction and an increased risk of sudden cardiac death. For patients with symptoms refractory to medica...
Conservative and Minimally Invasive Interventions for Temporomandibular Disorders: Protocol for a Systematic Review of Randomized Controlled Trials [0.03%]
针对颞下颌障碍的保守及微创干预措施：随机对照试验系统评价方案
Eugenia Larisa Tarevici,Oana Tanculescu,Alina Mihaela Apostu et al.
Eugenia Larisa Tarevici et al.
Background: Temporomandibular disorders (TMDs) are common musculoskeletal conditions associated with pain, functional limitation, and reduced quality of life (QoL). Despite the widespread use of conservative and minimally invasive treatment...
Diagnosis and Treatment of Nontraumatic Osteonecrosis of the Femoral Head: A Systematic Review and Meta-Analyses for the ARCO Clinical Practice Guideline Development Workgroup [0.03%]
股骨头非创伤性骨坏死的诊断和治疗：系统评价及荟萃分析（ARCO临床实践指南制定工作组）
Romil R Parikh,Alireza Mirzaei,Mary E Butler et al.
Romil R Parikh et al.
Background/objectives: Diagnostic evaluation and management of nontraumatic osteonecrosis of the femoral head (ONFH) vary substantially. This systematic review was conducted to inform development of the Association Resear...
Alpha-1 Antitrypsin Deficiency Beyond COPD and Emphysema: A Narrative Review [0.03%]
超支气管扩张症和肺气肿的α1抗胰蛋白酶缺乏症：叙述性综述
Lucia Pastoressa,Vanessa Pivetti,Marialuisa Valente et al.
Lucia Pastoressa et al.
Background/Objectives: Alpha-1 antitrypsin deficiency (AATD) is a genetic disorder classically associated with emphysema and COPD. However, emerging evidence indicates that its clinical spectrum extends to airway-predominant diseases such a...