Preoperative Botulinum Toxin Type A Use in Giant Inguinal Hernia Repair: A Scoping Review [0.03%]
肉毒杆菌素A在巨大腹股沟疝修补术中的应用:系统评价
Agostino Fernicola,Luigi Ricciardelli,Alessio Cece et al.
Agostino Fernicola et al.
Purpose: Giant inguinal hernias (GIHs) are rare and technically demanding conditions, associated with loss of domain and abdominal wall compliance. Preoperative botulinum toxin type A (BtxA) has been increasingly used in complex ventral her...
Current Insights into Clinical, Molecular, and Therapeutic Approaches to Acute Respiratory Distress Syndrome [0.03%]
急性呼吸窘迫综合征的临床、分子和治疗进展的新见解
Manuel Gonzalez-Plascencia,Margarita L Martinez-Fierro,Alfredo Salazar de Santiago et al.
Manuel Gonzalez-Plascencia et al.
Acute respiratory distress syndrome (ARDS) remains a leading cause of morbidity and mortality in critically ill patients despite advances in supportive care and lung-protective ventilation. The syndrome is characterized by biological hetero...
Use of Recombinant Human Deoxyribonuclease I in Primary Ciliary Dyskinesia Bronchiectasis-A Real Life Pilot Study [0.03%]
人重组脱氧核糖核酸酶I在原发性纤毛运动障碍支气管扩张症治疗中的应用——一项真实世界初步研究
Moshe Heching,Liora Slomianksy,Eviatar Naamany et al.
Moshe Heching et al.
Introduction: Recombinant human deoxyribonuclease I (rhDNase) cleaves DNA in mucus, facilitating increased mucociliary clearance of purulent sputum. In cystic fibrosis (CF), rhDNase improves pulmonary function and decreases exacerbations. C...
Artificial Intelligence in Cardiovascular Imaging: From Automated Acquisition to Precision Diagnostics and Clinical Decision Support [0.03%]
心血管影像中的人工智能:从自动化采集到精准诊断和临床决策支持
Minodora Teodoru,Alexandra-Kristine Tonch-Cerbu,Dragoș Cozma et al.
Minodora Teodoru et al.
Cardiovascular imaging is a cornerstone of modern cardiology, yet its clinical impact is limited by operator dependence, inter-observer variability, time-consuming workflows, and unequal access to advanced expertise. Artificial intelligence...
Chronic Obstructive Pulmonary Disease as an Independent Predictor of Left Main Coronary Artery Disease [0.03%]
慢性阻塞性肺疾病作为左主冠状动脉疾病的独立预测因子
Beatrice Ragnoli,Carlotta Bertelegni,Leonardo Brugiatelli et al.
Beatrice Ragnoli et al.
Background: Chronic obstructive pulmonary disease (COPD) is increasingly recognized as a disorder linked to increased cardiovascular risk, often coexisting with coronary artery disease (CAD), yet angiographic data on coronary involvement in...
The Effect of Viniferin on Liver Cancer: Research Based on Network Pharmacology, Molecular Docking and Molecular Dynamics Simulation [0.03%]
葡萄皮原花青素二聚体越橘素抗肝癌作用机制研究及分子动力学模拟验证
Saowanee Maungchanburi,Onwara Wongmek,Poolsak Baitahay et al.
Saowanee Maungchanburi et al.
Background/Objectives: Hepatocellular carcinoma (HCC) is a primary malignancy often driven by metabolic syndrome, fatty liver disease, and chronic hepatitis. These conditions foster a pro-inflammatory microenvironment that promotes tumor pr...
Remimazolam Bolus Prevents Emergence Agitation After Rhinologic Surgery: A Randomized, Triple-Blind, Controlled Trial [0.03%]
瑞米唑仑单次给药预防鼻窦手术后兴奋躁动的一项随机、三盲、对照研究
Grgur Prižmić,Filip Periš,Marinela Jozeljić Pešić et al.
Grgur Prižmić et al.
Background/Objectives: Emergence agitation (EA) is common after rhinologic surgery and may cause self-injury, bleeding, and prolonged post-anesthesia care unit (PACU) stay. Remimazolam is an ultra-short-acting benzodiazepine that may reduce...
Randomized Controlled Trial
Medical sciences (Basel, Switzerland). 2026 Mar 10;14(1):129. DOI:10.3390/medsci14010129 2026
The Signal in the Extreme: A Systematic Outlier Framework Identifies Discrete Immunometabolic Subtypes in Human and Cellular Models [0.03%]
极端中的信号:一种系统性异常值框架识别出人类和细胞模型中的离散免疫代谢亚型
Julio Jesús Garcia-Coste,Karla Aidee Aguayo-Cerón,Judith Espinosa-Raya et al.
Julio Jesús Garcia-Coste et al.
Background: Conventional omics analysis often treats outliers as noise, yet they may harbor critical biological insights. Objetive: Thi...
Epicardial Adipose Tissue as a Cardiometabolic Target in Atrial Fibrillation: Implications for Ablation Strategies and Emerging Metabolic Therapies [0.03%]
心房颤动中 epicardial 脂肪组织作为心血管代谢治疗靶点的意义:射频消融策略和新兴代谢疗法的启示
Fulvio Cacciapuoti
Fulvio Cacciapuoti
Background: Atrial fibrillation (AF) is a prevalent arrhythmia closely associated with cardiometabolic disorders and systemic inflammation. Epicardial adipose tissue (EAT), located in direct contact with the atrial myocar...
Combination of Antidepressants and Chemotherapeutic Agents to Overcome P-Glycoprotein-Mediated Resistance in Cancer Patients: A Systematic Review [0.03%]
克服癌症患者P-糖蛋白介导的耐药性的抗抑郁剂和化疗药物联合用药:系统性综述
Antonio Restaino,Mario Pinto,Giulio Carriero et al.
Antonio Restaino et al.
Background/Objectives: P-glycoprotein (P-gp, ABCB1/MDR1) is a key ATP-binding cassette transporter involved in multidrug resistance in cancer, limiting intracellular accumulation of various chemotherapeutic (CT) agents. Several antidepressa...