Chronic Stress, Immune Suppression, and Cancer Occurrence: Unveiling the Connection Using Survey Data and Predictive Models [0.03%]
慢性压力、免疫抑制与癌症发生率：利用调查数据和预测模型揭示关联性
Teddy Lazebnik,Vered Aharonson
Teddy Lazebnik
Chronic stress has been implicated in cancer occurrence, but a direct causal connection has not been consistently established. Machine learning and causal modeling offer opportunities to explore complex causal interactions between psycholog...
Depression and Suicidality in Patients with Left Ventricular Assist Devices and Advanced Cardiac Therapies: Mechanisms, Risk Factors, and Clinical Management [0.03%]
左心室辅助装置和晚期心脏治疗患者的抑郁和自杀倾向：机制、危险因素及临床管理
Vasileios Leivaditis,Francesk Mulita,Chrysa Andrikopoulou et al.
Vasileios Leivaditis et al.
Background: The increasing use of advanced cardiac surgical therapies, particularly left ventricular assist devices (LVADs), has improved survival in patients with end-stage heart failure. However, the psychological burde...
Beyond PSA-Can Systemic Inflammatory Indices Improve Prostate Cancer Detection? [0.03%]
超越PSA水平——系统性炎症指标能改善前列腺癌的诊断吗？
Marius Ivănuță,Abdallah Shurrab,Dragoș Puia et al.
Marius Ivănuță et al.
Background: Prostate-specific antigen (PSA) remains the primary biomarker for prostate cancer detection; however, its limited specificity leads to unnecessary biopsies. Systemic inflammatory indices derived from routine b...
Observational Study
Medical sciences (Basel, Switzerland). 2026 May 7;14(2):243. DOI:10.3390/medsci14020243 2026
Optimizing Precision Oncology: Structural Frameworks for Local MTB Integration and Outcome Assessment [0.03%]
精准肿瘤学的优化：局部MTB整合和结果评估的结构框架
Nicoleta Zenovia Antone,Flaviu Andreicovici,Andrada Larisa Deac et al.
Nicoleta Zenovia Antone et al.
Background/objectives: Molecular tumor profiling has recently transformed oncologic care delivery, establishing precision medicine as an essential approach for defining cancer biology and revealing intratumoral heterogene...
Early Endothelial Injury in Pancreas Transplantation: Insights from a Prospective Cohort Largely Composed of Simultaneous Pancreas-Kidney Recipients [0.03%]
胰腺移植早期内皮损伤：来自以同时 pancreas-kidney 移植受者为主的前瞻性队列的启示
Joana Ferrer-Fàbrega,Andrea Llaves-López,Ramón Rull et al.
Joana Ferrer-Fàbrega et al.
Background/objectives: Ischemia-reperfusion injury (IRI) contributes to graft dysfunction in solid organ transplantation, with the pancreas vulnerable due to its fragile vasculature. Endothelial glycocalyx (eGCX) disrupti...
Mesenchymal Stem Cell-Derived Extracellular Vesicles and Plant-Derived Nanovesicles as Cell-Free Therapies for Thermal Burn Healing: A Systematic Review of Preclinical Evidence and Delivery Strategies [0.03%]
基于间充质干细胞和植物来源的细胞外囊泡用于烧伤修复的无细胞治疗：前期证据及给药策略的系统性综述
Alexandru Hristo Amarandei,Stefana Avadanei-Luca,Andra-Irina Bulgaru-Iliescu et al.
Alexandru Hristo Amarandei et al.
Background/Objectives: Thermal injuries represent a significant global health burden, often complicated by hypertrophic scarring, chronic inflammation, and delayed re-epithelialization. While Mesenchymal Stem Cell (MSC) transplantation has ...
The Early Effect of Alendronate, Hop Extract and Their Combination on Bone Structural Properties in a Rat Model of Osteoporosis [0.03%]
早期阿仑膦酸钠、槐米提取物及其联合应用对骨质疏松大鼠骨结构性能的影响研究
Edi Rođak,Robert Grgac,Rok Kostanjšek et al.
Edi Rođak et al.
Background/Objectives: New approaches using plant-based extracts are increasingly investigated for osteoporosis treatment, including hop extract, which contains potent compounds that favorably affect bone quality. The objective of this rese...
Unsupervised Immune Profiling Identifies Distinct Post-Transplant T-Cell Clusters Associated with Kidney Allograft Function [0.03%]
无监督免疫组学分析鉴定出与移植肾功能相关的特异性T细胞簇
Lampros Vagiotas,Asimina Fylaktou,Ariadni Fouza et al.
Lampros Vagiotas et al.
Background: Post-transplant immune heterogeneity may influence kidney allograft outcomes, yet the clinical relevance of circulating T-cell phenotypes remains incompletely defined. We aimed to identify 12-month post-transp...
Test-Retest Reliability of a Performance-Based Test Battery in Patients with Fibromyalgia According to Socio-Occupational Status [0.03%]
基于社会职业状态的纤维肌痛患者性能测试量表的重测信度研究
José Luis Socorro-Cumplido,Blanca Roman-Viñas,Miriam Almirall et al.
José Luis Socorro-Cumplido et al.
Background: Performance-based tests (PBTs) objectively assess functional capacity and are increasingly applied in fibromyalgia (FM) to complement patient-reported outcomes (PROMs). However, evidence regarding their reliab...
Endostemonine I as a Multi-Target Inhibitor of Kaposi's Sarcoma-Associated Herpesvirus Oncogenic Pathways: An Integrative Computational Study [0.03%]
内皮蒙花碱I作为卡波西肉瘤相关疱疹病毒致癌通路多靶标抑制剂的整合计算研究
Imran Sama-Ae,Mollaya Daloh,Aman Tedasen et al.
Imran Sama-Ae et al.
Background/Objectives: Kaposi's sarcoma (KS) is an angioproliferative malignancy caused by Kaposi's sarcoma-associated herpesvirus (KSHV), characterized by aberrant angiogenesis, chronic inflammation, and endothelial cell transformation. Gi...