Integrated FTIR and Whole-Genome Sequencing Reveal Scale-Dependent Genotype-Phenotype Relationships in Multidrug-Resistant Pseudomonas aeruginosa [0.03%]
整合FTIR和全基因组测序揭示了多重耐药铜绿假单胞菌表型与基因型的关系
György Lengyel,Eszter Kaszab,Enikő Fehér et al.
György Lengyel et al.
Multidrug-resistant Pseudomonas aeruginosa is a major cause of healthcare-associated infections, particularly in high-burden clinical settings where rapid tools to capture clinically relevant resistance and virulence phenotypes are needed. ...
Epidemiological Characteristics of Dengue Disease in Mexico (2014-2025): A Descriptive Analysis of a Hyperendemic Country [0.03%]
墨西哥登革热的流行病学特征（2014-2025）：一个高度地方性国家的描述性分析
Rosa Cremades,Elena Sandoval-Pinto,Ana Maria Ortega-Prieto et al.
Rosa Cremades et al.
Dengue is considered the most prevalent mosquito-borne arboviral disease worldwide, representing a public health challenge as its incidence has tripled in the last 30 years. The World Health Organization reports 390 million infections annua...
Elevated Antibacterial Activity of a Polygalacturonic + Caprylic Acids Wound Ointment Compared with Hypochlorous Acid in a Three-Dimensional Wound Biofilm Model [0.03%]
聚半乳糖醛酸+辛酸伤口软膏的抗菌活性高于次氯酸的三维伤口生物膜模型中的研究
Bahgat Gerges,Joel Rosenblatt,Y-Lan Truong et al.
Bahgat Gerges et al.
Bacterial biofilms play a major role in delayed wound-healing and in the development of chronic, non-healing wounds. Natural, plant-based agents, which can eradicate bacterial biofilms, are alternatives to antibiotics and antiseptics in the...
Single Isothermal Assay for Multi-Site Mutation Detection of Rifampicin Resistance in Mycobacterium tuberculosis [0.03%]
用于检测结核分支杆菌利福平耐药多靶点突变的单管等温方法筛查技术研究
Nidhi Nandu,Michael Miller,Zhi-Xiang Lu
Nidhi Nandu
Antimicrobial drug resistance is an escalating global health burden, often driven by multiple genetic changes within key resistance-associated genes. Achieving multiplex capability of mutation detection while maintaining simplicity and affo...
Molecular Pathways Driving Corneal Neovascularization in Herpes Simplex Keratitis [0.03%]
HSV角膜炎新生血管化分子通路研究进展
Soromidayo Akinsiku,Deepak Shukla
Soromidayo Akinsiku
Herpes simplex keratitis (HSK) is classically described as an immunopathological disease driven by recurrent herpes simplex virus type 1 (HSV-1) infection and chronic inflammation. So far, immune-mediated tissue damage has not fully explain...
HTD1265 Disrupts GimC-Dependent Cellular Processes in Saccharomyces cerevisiae [0.03%]
HTD1265干扰Saccharomyces cerevisiae中的GimC依赖性细胞过程
Kaori Itto-Nakama,Naoya Hosoyamada,Shinsuke Ohnuki et al.
Kaori Itto-Nakama et al.
HTD1265 is a newly identified antifungal compound that displays potent activity against Candida krusei, a clinically challenging non-albicans species. To elucidate its mechanism of action, we applied an integrative phenotypic approach combi...
Helicobacter pylori Neutrophil Activating Protein (HP-NAP) Enhances the Anti-Leishmanial Activity of Canine Macrophages Against Leishmania infantum [0.03%]
根除幽门螺杆菌中和激活蛋白增强犬单核细胞抗利什曼原虫活性
Gaia Mazza,Federica Perego,Sara Coletta et al.
Gaia Mazza et al.
Leishmania infantum is the etiological agent of visceral leishmaniasis (VL) and is linked to cases of cutaneous leishmaniasis in dogs. Dogs often develop severe systemic disease and serve as the primary reservoir of L. infantum. Although se...
Microbiological Spectrum and Antimicrobial Resistance Patterns in Hand Surgery Infections: A Monocentric Retrospective Study [0.03%]
一项关于手外科手术感染的微生物光谱和抗菌药物耐药模式的单中心回顾性研究
Lorenzo Drago,Fabiana Giarritiello,Deflorio Loredana et al.
Lorenzo Drago et al.
Background: Infections in hand surgery represent a clinically relevant complication, particularly in trauma-related procedures and in the presence of internal fixation devices. Data specifically addressing microbiological profiles and antim...
Molecular Lineage Replacement and Shifted Seasonality of Pediatric Respiratory Syncytial Virus on Tropical Hainan Island, China, 2021-2024 [0.03%]
中国海南岛2021-2024年儿科呼吸道合胞病毒的分子谱系更替和季节变化
Yibo Jia,Siqi Chen,Shannan Wu et al.
Yibo Jia et al.
Respiratory syncytial virus (RSV) resurged in many regions after the relaxation of stringent non-pharmaceutical interventions (NPIs) implemented during the COVID-19 pandemic. Here, we characterized the epidemiological patterns and molecular...
Silent Intruders: The Gut Virome in Brain Aging and Cognitive Decline [0.03%]
潜入者：肠道病毒组与大脑衰老和认知衰退的关系
Serena Silvestro,Angelina Midiri,Carmelo Biondo et al.
Serena Silvestro et al.
Recent advances in next-generation sequencing have revealed that the virome-the set of viruses residing in the gastrointestinal tract-is a fundamental yet still underexplored component of the human intestinal ecosystem. Despite the prevalen...