Genome-Wide Association Reveals Signalling-Linked Infection Tolerance in Hibernating Bats [0.03%]
基因组广义关联揭示冬眠蝙蝠感染容忍的信号联系
Markéta Harazim,Lubomír Piálek,Hana Bandouchova et al.
Markéta Harazim et al.
Hibernation profoundly alters host-pathogen dynamics by suppressing metabolism and immune function, posing unique challenges for infection control. In this study, we examined how genomic variation modulates infection and physiological trait...
Ligilactobacillus agilis LA-V4 Isolated from Vulture Fecal Isolate: A Novel Probiotic Candidate with Broad-Spectrum Antibacterial Activity [0.03%]
从兀鹫粪便中分离的 Ligilactobacillus agilis LA-V4：一种具有广谱抗菌活性的新颖益生菌候选菌株
Siyuan Li,Chuxian Quan,Muhammad Farhan Rahim et al.
Siyuan Li et al.
Vultures are extraordinarily adapted to feed on carrion, providing them with a constant microbiologically hostile environment. This peculiar ecological position has influenced the evolution of their gut microbiota, potentially conferring it...
Age-Dependent Dynamics of the Biliary Microbiome in Children with Choledochal Cysts: Functional Remodeling Underlying Taxonomic Conservation [0.03%]
儿童胆总管囊肿中胆道微生物组的年龄依赖性动态变化：分类学保守性下的功能重塑
Xueqi Wang,Ran Duan,Anxiao Ming et al.
Xueqi Wang et al.
Choledochal cyst (CC), a congenital biliary anomaly, is associated with recurrent infections, chronic inflammation, and an increased risk of malignancy. Although emerging evidence implicates the biliary microbiome in disease pathophysiology...
Assessment of the Pathogenicity of Candidatus Rickettsia Colombiensis in a Syrian Hamster Model and Serological Cross-Reactivity Between Spotted Fever Rickettsia Species [0.03%]
巴氏顿体立克次体科隆比亚斯亚种在叙利亚仓鼠模型中的致病性评价及恙热立克次体种属之间的血清交叉反应性研究
Jorge Miranda,Alejandra García,Cristina Cervera-Acevedo et al.
Jorge Miranda et al.
Candidatus Rickettsia colombiensis is a new candidate species of Rickettsiae spotted fever group that have been isolated only from ticks. The pathogenicity of Ca. R. colombiensis to human and animals is unknown. This study evaluated the pat...
Evaluation of Multi-Target Genotyping (ITS- hsp70- cpb) for Detecting Population Heterogeneity Within Mediterranean Leishmania infantum, with a Focus on Zymodeme MON-24 [0.03%]
用于检测地中海利什曼原虫群体异质性的多靶标基因分型（ITS- hsp70- cpb）的评估，重点关注Zymodeme MON-24
Trentina Di Muccio,Daniele Tonanzi,Gert Van der Auwera et al.
Trentina Di Muccio et al.
L. infantum and L. donovani, distinct species in the L. donovani complex, show high phenotypic and genotypic polymorphism and share molecular traits. Therefore, genotyping by a single molecular target can give uncertain results. This study ...
Detection of HIV-1 Resistance Mutations to Antiretroviral Therapy and Cell Tropism in Russian Patients Using Next-Generation Sequencing [0.03%]
基于新一代测序技术的俄罗斯艾滋病患者人免疫缺陷病毒抗逆转录病毒药物耐药性突变及嗜细胞 tropism检测
Artem Fadeev,Veronika Eder,Maria Pisareva et al.
Artem Fadeev et al.
The use of antiretroviral therapy (ART) as the only effective way to control human immunodeficiency virus (HIV) infection results in HIV drug resistance. Next-generation sequencing (NGS) has become a common method for identifying drug-resis...
Phenotypic and Molecular Characterization of Clinical Isolates of Vancomycin-Resistant Enterococcus faecium in the Health District of Bolzano (Italy) During 2021-2023 [0.03%]
2021至2023年意大利博尔扎诺卫生区万古霉素耐药粪肠球菌临床分离株的表型和分子特征分析
Angela Maria Di Pierro,Richard Aschbacher,Maria Del Grosso et al.
Angela Maria Di Pierro et al.
Vancomycin-resistant Enterococcus faecium (VREfm) is an emerging pathogen responsible for healthcare-associated infections. For this reason, 44 VREfm isolates collected during 2021-2023 were characterized using phenotypic and genomic approa...
Clinical, Laboratory, and Therapeutic Characteristics of Visceral Leishmaniasis with Emphasis on Immune Status: A Multicentre Cohort Study in Greece [0.03%]
基于希腊多中心队列的黏膜皮肤利什曼病临床、实验室及治疗特征（重点免疫状态）
Aristos Aristodimou,Achilleas Gikas,Maria Antoniou et al.
Aristos Aristodimou et al.
Visceral leishmaniasis (VL) is an endemic zoonotic disease in southern Europe with increasing clinical relevance among immunocompromised populations; however, detailed clinical data remain scarce. This retrospective multicentre cohort study...
Tuberculosis Diagnostic Methods: Clinical Applicability, Implementation Challenges, and Integrated Testing Strategies [0.03%]
结核病诊断方法：临床适用性、实施挑战及整合检测策略
Eduarda Rabello,Fernanda de-Paris
Eduarda Rabello
Tuberculosis (TB) remains one of the leading causes of death from a single infectious agent worldwide, a burden further exacerbated by HIV co-infection and the increasing prevalence of drug-resistant strains. Although a wide range of labora...
The Fires of Isengard Have Spread: Serratia sarumanii Is the Dominant Species in Clinical Isolates of the " Serratia marcescens Complex" [0.03%]
伊萨嘉德之火已蔓延：“肠杆菌科沙雷氏菌群”中分离出的临床标本以产红色色素沙雷氏菌为主
Levin Joe Klages,Julia Hassa,Tobias Busche et al.
Levin Joe Klages et al.
Recently, a new species, Serratia sarumanii, was described, belonging to a group of strains previously identified as Serratia marcescens in routine clinical analyses. It was shown that the identification of S. marcescens isolates by biochem...