Abiraterone Acetate Affects Gene Expression Profile in a Human Male Neuronal Cell Line: Potential Mechanism for Cognitive Deficits with Prostate Cancer Therapy [0.03%]
阿比特龙影响人类雄性神经细胞系的基因表达谱：前列腺癌治疗时出现认知缺陷的潜在机制
Shelly Gulkarov,Allison B Reiss,Ankita Srivastava et al.
Shelly Gulkarov et al.
Background and objectives: Cornerstone therapies for metastatic prostate cancer include androgen deprivation and androgen receptor pathway inhibition, but cognitive impairment is a recognized, life-altering potential adve...
Early Real-World Experience of Switching to Faricimab for Macular Oedema Secondary to Vein Occlusion [0.03%]
远视网膜静脉阻塞引起的黄斑水肿患者转换为Faricimab治疗的早期真实世界经验
Muiz Musadiq,Emer Chang,Abison Logeswaran et al.
Muiz Musadiq et al.
Aim: To evaluate the real-world effectiveness, durability, and safety of faricimab 6 mg in eyes with treatment-refractory retinal vein occlusion (RVO)-associated macular oedema (MO) in the United Kingdom (UK). ...
Sex- and Gender-Related Differences in Pruritus in Dermatological Diseases: Insights into Inflammatory, Autoimmune, and Connective Tissue Disorders [0.03%]
皮肤病学中炎症、自身免疫和结缔组织疾病的相关瘙痒的性别差异分析
Francesca Gorini,Alice Verdelli,Alessandro Magnatta et al.
Francesca Gorini et al.
Pruritus is a common and burdensome symptom in inflammatory, autoimmune, and connective tissue skin diseases, significantly impairing quality of life, sleep, and psychological well-being. Pruritus arises from a complex interplay between ski...
Proteome of CD9+ Plasma Small Extracellular Vesicles Differentiates Stages of HPV-Associated Cervical Neoplasia from Normal Epithelium to Invasive Cancer [0.03%]
用于区分人乳头瘤病毒相关宫颈上皮内病变和浸润性癌的CD9+血浆小细胞外囊泡蛋白质组学研究
Alexander M Yurin,Natalia L Starodubtseva,Anna E Bugrova et al.
Alexander M Yurin et al.
Human papillomavirus (HPV)-associated cervical lesions remain a significant disease burden and minimally invasive blood-based biomarkers could complement cytology and HPV testing. This study aimed to characterize the proteomic composition o...
Propolis and Caffeic Acid Phenethyl Ester Attenuate Oxidative and Nitrosative Stress in Rat Kidney Tissue After Cranial Irradiation [0.03%]
propolis和咖啡酸苯乙酯减轻颅脑放疗后的肾脏组织的氧化应激及亚硝基应激
Aziz Bulut,Oztekin Cikman,Seyithan Taysi
Aziz Bulut
Radiation-induced bystander effect (RIBE) contributes to oxidative and nitrosative stress in non-irradiated tissues following ionizing radiation (IR). This study investigated the protective effects of propolis and caffeic acid phenethyl est...
Transseptal Access to the Left Atrium: A Narrative Review of Techniques, Indications, and Device Innovations [0.03%]
左心房室间隔通路的获取：技术、指征和器械创新综述
Andrei Mihnea Rosu,Theodor Georgian Badea,Florentina Luminita Tomescu et al.
Andrei Mihnea Rosu et al.
Transseptal puncture (TSP) is a critical technique for accessing the left atrium in various structural and electrophysiological cardiac procedures. Originally introduced for diagnostic catheterization in the mid-20th century, it has evolved...
Beyond Screen Time: A Measurement Framework for Behavioral Exposures in Childhood Myopia [0.03%]
超越屏幕时间：儿童近视行为暴露测量框架
Jeong Jun Park,Gwi Eun Yeo,Youra Kim et al.
Jeong Jun Park et al.
Childhood myopia is increasingly discussed in relation to digital device use, yet total screen duration is biologically nonspecific (not tied to a single biological cause) and may combine outdoor-light deficit, near work intensity, educatio...
MALDI-MSI-Guided Laser Capture Microdissection Coupled with MS for Integrated Spatial Multi-Omics in Mouse Brain [0.03%]
基于MALDI-MSI引导的激光捕获显微解剖结合质谱的多组学空间整合研究小鼠大脑的方法
Byoung-Kyu Cho,Jessica K Lukowski,Minsoo Son et al.
Byoung-Kyu Cho et al.
Spatial multi-omics analyzes biomolecules such as the proteome, metabolome, and lipidome within their native spatial context in tissues or cells. Mass spectrometry imaging (MSI) has emerged as a powerful technique for mapping the region-spe...
Clinical Prognostic Factors and Survival Risk Stratification for Advanced Biliary Tract Cancer Treated with Gemcitabine-Based Palliative Chemotherapy: A Real-World Retrospective Study [0.03%]
基于吉西他滨姑息化疗的 advanced biliary tract癌患者的临床预后因素及生存风险分层：一项回顾性真实世界研究
Jirapat Wonglhow,Arunee Dechaphunkul,Patrapim Sunpaweravong et al.
Jirapat Wonglhow et al.
Background: Although gemcitabine-based palliative chemotherapy remains widely used for advanced biliary tract cancer (BTC), practical pretreatment prognostic factors are needed. This study identified baseline prognostic f...
Behavioral and Structural Correlates of Axial Length in School-Aged Children: Baseline Findings from the Seoul Myopia Cohort Study [0.03%]
学龄儿童眼轴长度的行为学和结构性影响因素：首尔近视队列研究基线结果报告
Ju-Yeun Lee,Chang Hwan Lee,Kyungsik Kim et al.
Ju-Yeun Lee et al.
Digital device use has substantially altered children's visual environments, yet the specific behaviors associated with axial elongation and early retinal remodeling remain unclear in highly urbanized settings. This study investigated biolo...