Evaluation of 3,3'-Triazolyl Biisoquinoline N, N'-Dioxide Catalysts for Asymmetric Hydrosilylation of Hydrazones with Trichlorosilane [0.03%]
评估3,3'-三唑基双异喹啉N，N'-二氧化物催化剂用于二氯硅烷与羟胺的不对称氢甲硅烯化反应
Shiyu Sun,Changgong Xu,Jamielyn Jarvis et al.
Shiyu Sun et al.
A new class of axial-chiral biisoquinoline N,N'-dioxides was evaluated as catalysts for the enantioselective hydrosilylation of acyl hydrazones with trichlorosilane. While these catalysts provided poor to moderate reactivity and enantiosele...
Nuclear Resonance Vibrational Spectroscopy: A Modern Tool to Pinpoint Site-Specific Cooperative Processes [0.03%]
核共振振动光谱：一种定位特定位置的协作过程的现代工具
Hongxin Wang,Artur Braun,Stephen P Cramer et al.
Hongxin Wang et al.
Nuclear resonant vibrational spectroscopy (NRVS) is a synchrotron radiation (SR)-based nuclear inelastic scattering spectroscopy that measures the phonons (i.e., vibrational modes) associated with the nuclear transition. It has distinct adv...
Asymmetric Catalytic Ketimine Mannich Reactions and Related Transformations [0.03%]
不对称催化的酮亚胺Mannich反应及相关的转化反应
Changgong Xu,Carlyn Reep,Jamielyn Jarvis et al.
Changgong Xu et al.
The catalytic enantioselective ketimine Mannich and its related reactions provide direct access to chiral building blocks bearing an α-tertiary amine stereogenic center, a ubiquitous structural motif in nature. Although ketimines are often...
The HD-Domain Metalloprotein Superfamily: An Apparent Common Protein Scaffold with Diverse Chemistries [0.03%]
HD结构域金属酶超家族：一个通用的蛋白骨架和多样的化学物质体系
Michelle Langton,Sining Sun,Chie Ueda et al.
Michelle Langton et al.
The histidine-aspartate (HD)-domain protein superfamily contains metalloproteins that share common structural features but catalyze vastly different reactions ranging from oxygenation to hydrolysis. This chemical diversion is afforded by (i...
Indole C6 Functionalization of Tryprostatin B Using Prenyltransferase CdpNPT [0.03%]
tryprostatin B的吲哚C6修饰及其环化产物TBpyri的合成与生物活性研究
Eric D Gardner,Dustin A Dimas,Matthew C Finneran et al.
Eric D Gardner et al.
Tryprostatin A and B are prenylated, tryptophan-containing, diketopiperazine natural products, displaying cytotoxic activity through different mechanisms of action. The presence of the 6-methoxy substituent on the indole moiety of tryprosta...
Activated Carbon as a Cathode for Water Disinfection through the Electro-Fenton Process [0.03%]
用于电芬顿过程的活性炭灭菌阴极的研究
Long Chen,Ameet Pinto,Akram N Alshawabkeh
Long Chen
Unlike many other water disinfection methods, hydroxyl radicals (HO•) produced by the Fenton reaction (Fe2+/H2O2) can inactivate pathogens regardless of taxonomic identity of genetic potential and do not generate halogenated disinfection b...
Immobilization of β-Galactosidases on the Lactobacillus Cell Surface Using the Peptidoglycan-Binding Motif LysM [0.03%]
利用肽聚糖结合基序LysM将β-半乳糖苷酶固定于乳杆菌细胞表面
Mai-Lan Pham,Anh-Minh Tran,Suwapat Kittibunchakul et al.
Mai-Lan Pham et al.
Lysin motif (LysM) domains are found in many bacterial peptidoglycan hydrolases. They can bind non-covalently to peptidoglycan and have been employed to display heterologous proteins on the bacterial cell surface. In this study, we aimed to...
Immobilization of an Endo-β- N-acetylglucosaminidase for the Release of Bioactive N- glycans [0.03%]
一种内切-β-N-乙酰氨基葡萄糖苷酶的固定化释放生物活性N-聚糖基序的研究
Joshua L Cohen,Sercan Karav,Daniela Barile et al.
Joshua L Cohen et al.
As more is learned about glycoproteins' roles in human health and disease, the biological functionalities of N-linked glycans are becoming more relevant. Protein deglycosylation allows for the selective release of N-glycans and facilitates ...
Alkanethiolate-Capped Palladium Nanoparticles for Regio- and Stereoselective Hydrogenation of Allenes [0.03%]
用于allen烃区域选择性和立体选择性氢化的硫醇盐封端的钯纳米粒子
Ting-An Chen,Young-Seok Shon
Ting-An Chen
Colloidal Pd nanoparticles capped with octanethiolate ligands have previously shown an excellent selectivity toward the mono-hydrogenation of both isolated and conjugated dienes to internal alkenes. This paper reports an efficient stereosel...
In Silico Studies of Small Molecule Interactions with Enzymes Reveal Aspects of Catalytic Function [0.03%]
基于计算的小分子与酶相互作用研究揭示了催化功能的机制属性
Rajni Verma,Katie Mitchell-Koch
Rajni Verma
Small molecules, such as solvent, substrate, and cofactor molecules, are key players in enzyme catalysis. Computational methods are powerful tools for exploring the dynamics and thermodynamics of these small molecules as they participate in...