Algicidal Monoterpenes Against Toxin-Producing Microcystis aeruginosa with Reduced Toxicity Toward Chlorella sorokiniana: In Vitro, Molecular Docking, and ADMET Study [0.03%]
一种单萜藻杀菌剂可有效抑制微囊藻毒素的产生且对小球藻毒性较低：体外实验，分子对接和药物代谢动力学研究
El Mehdi Darrag,Yasser Essadki,Saad Zekri et al.
El Mehdi Darrag et al.
Harmful algal blooms pose a persistent threat to the integrity of freshwater ecosystems and public health. However, there are no selective chemical control agents available to suppress cyanobacterial growth without damaging beneficial phyto...
Recombinant Human Fab Antibodies Differentially Neutralize Shiga Toxin in Renal Epithelial and Endothelial Cells [0.03%]
重组人源Fab抗体在肾上皮细胞和内皮细胞中对志贺毒素的中和作用不同
Fernando D Gómez,Daniela Luz,Isabel Chinen et al.
Fernando D Gómez et al.
Hemolytic Uremic Syndrome (HUS) is a severe clinical manifestation primarily triggered by Shiga toxin-producing Escherichia coli (STEC). While Shiga toxins (Stx) are central to the development of systemic endothelial damage, current recombi...
Qualitative and Quantitative Proteomic Analysis of Venoms from Mexican Rattlesnakes [0.03%]
墨西哥响尾蛇毒液的质谱与量化蛋白质组分析研究进展
Lizbeth Hernández-Ancheyta,Víctor Hugo Reynoso,Juan Carlos López-Vidal et al.
Lizbeth Hernández-Ancheyta et al.
Despite the vast biodiversity of Mexican vipers, venom of endemic species has been barely studied. Here we analyzed the venom composition of three endemic species of rattlesnakes: Crotalus aquilus, C. triseriatus, and C. ravus. We used quan...
Unveiling Hidden Aconitum Alkaloids in a Poisoning-Implicated Tincture by Untargeted Screening and Molecular Networking [0.03%]
通过非目标筛选和分子网络挖掘中毒事件中的未知附子生物碱成分
Qian He,Micong Jin,Jing Zhou et al.
Qian He et al.
Aconitum poisoning is a major public health concern in East Asia, and remains difficult to diagnose when the causative toxins are not covered by routine targeted assays. In a poisoning incident that occurred in 2018, 15 individuals were aff...
Effects of the Temperature and Limosilactobacillus fermentum Co-Inoculation on the Expression of AFB1-Synthesis Genes and the Level of Toxin Produced by Aspergillus flavus Zt41 in Corn Silage [0.03%]
温度和发酵乳杆菌共接种对玉米青贮中AFB1合成基因表达及Zt41产毒量的影响
Szilamér Ferenczi,Ildikó Bata-Vidács,Judit Kosztik et al.
Szilamér Ferenczi et al.
Aflatoxin B1 (AFB1), a highly potent Group 1 human carcinogen produced by Aspergillus flavus (A. flavus), poses a significant contamination risk to corn silage, a threat that is further intensified by rising global temperatures. This study ...
Facial Paralysis Treatment and Facial Symmetrization with Botulinum Neurotoxin: A Narrative Review with Illustrative Clinical Cases [0.03%]
肉毒杆菌毒素用于面部瘫痪治疗及改善面肌不对称的治疗：回顾性研究及临床案例分析
Monica Renga,Roberta D&#x;Emilio,Giovanni Salti et al.
Monica Renga et al.
Facial paralysis leads to static and dynamic asymmetry, hyperkinesis of the non-paralyzed side, and synkinesis, with major functional and psychosocial consequences for patients. Botulinum neurotoxin serotype A (BoNT-A) injections are an eff...
Cyclopiazonic Acid Induces Mitochondrial Oxidative Stress in SH-SY5Y Cells: Protective Effects of Extra Virgin Olive Oil Phenolics [0.03%]
肉桂花生酸通过SH-SY5Y细胞中的线粒体诱导氧化应激：特级初榨橄榄油酚类的保护作用
Carmen Martínez-Alonso,Yelko Rodríguez-Carrasco,María-José Ruiz
Carmen Martínez-Alonso
Cyclopiazonic acid (CPA), a neurotoxin produced by Penicillium and Aspergillus genera, induces oxidative stress and neuronal damage, mechanisms implicated in neurodegenerative diseases. This study investigates the oxidative stress induced b...
Biopesticidal Properties of the Probiotic Brevibacillus laterosporus Strain B.O.D [0.03%]
枯草芽孢杆菌B.O.D菌株的生物杀虫特性研究
M Florencia Gil,Alessia Vinci,Manuela Casada et al.
M Florencia Gil et al.
Brevibacillus laterosporus strain B.O.D. is a well-established commercial probiotic and antimicrobial microorganism that finds use in human health and in agriculture as a biofertilizer. On the other hand, while B. laterosporus is a well-kno...
Burden of Mortality and Morbidity Caused by Snakebites Contributes to Economic Loss in a Rural Population in India [0.03%]
印度农村人口蛇咬引起的生命和健康损失对经济损失的影响
Swapnil Kiran,Siripuram Srinivas,Karthikeyan Vasudevan
Swapnil Kiran
Snakebite envenoming is a major public health concern in India that causes economic hardship for the rural populations. We estimated the per capita economic burden of snakebites in a rural population by quantifying mortality and morbidity r...
Analgesic and Neurorestorative Effects of αO-Conotoxin GeXIVA[1,2] in Diabetic Neuropathic Pain and Postherpetic Neuralgia [0.03%]
αO-康托克斯汀GeXIVA[1,2]在糖尿病神经痛和带状疱疹后遗神经痛中的镇痛及神经营养作用
Rongyan He,Shuting Xiao,Xiaoying Liang et al.
Rongyan He et al.
Chronic neuropathic pain, particularly diabetic neuropathic pain and postherpetic neuralgia, severely impairs patients' quality of life due to their complex mechanisms and recurrent, long-term nature, making treatment challenging. This stud...