Enniatins and Beauvericin as Emerging Mycotoxins in the Context of Climate Change in Europe [0.03%]
欧洲气候变化背景下恩尼汀和 beauvericin 成为新兴霉菌毒素
Francesca De Battistis,Chiara Civitelli,Valentina Prota et al.
Francesca De Battistis et al.
Emerging mycotoxins are unregulated natural toxins, often detected in small-grain cereal crops. They are produced by various Fusarium molds and have been reported in surveys conducted across Europe. Many Fusarium species that produce mycoto...
The Battle Against Pertussis: Discovery of Endogenous Human Proteins and Peptides as Toxin-Inhibitors [0.03%]
百日咳攻坚战：发现内源性人抑毒蛋白及肽类化合物
Stefanie Lietz,Holger Barth
Stefanie Lietz
The life-threatening disease pertussis, also known as whooping cough, is caused by a complex interplay of several virulence factors produced by the bacterium Bordetella (B.) pertussis. These include the AB-type protein toxin pertussis toxin...
Nela Drača,Sunčana Včelik,Rudolf Krska et al.
Nela Drača et al.
For centuries, bee pollen has been known for its medicinal value and regarded as a rich source of bioactive compounds, including essential nutrients and phytochemicals. Its putative therapeutic and health-promoting benefits include antioxid...
Development of an Automated Cell-Based Assay for the Detection of the Functional Activity of Saxitoxin [0.03%]
用于检测石房蛤毒素功能活性的自动化细胞基质测定法的开发
Rachel Whiting,Isobel Picken,Grace Howells et al.
Rachel Whiting et al.
Saxitoxin (STX) is one of the most potent natural neurotoxins known and is the only marine toxin to be declared a chemical weapon. In both marine and freshwater systems filter feeding organisms can accumulate saxitoxin and human consumption...
Design and Characterization of Recombinant and Chimeric BoNT/A Neurotoxins with Receptor-Binding Domain Grafting [0.03%]
具有结合域嫁接的重组型和嵌合型肉毒杆菌素/A神经毒素的设计与表征
Sihan Pan,Yuanzhi Ye,Yang Li et al.
Sihan Pan et al.
Botulinum neurotoxins (BoNTs) act on peripheral cholinergic nerve terminals, inducing reversible muscle paralysis and profound therapeutic effects. However, their limited cell-type specificity and narrow therapeutic window have motivated th...
Svetlana V Malysheva
Svetlana V Malysheva
Natural toxins constitute a large group of toxic compounds produced by plants, fungi, bacteria and other organisms [...].
Editorial
Toxins. 2026 Apr 28;18(5):204. DOI:10.3390/toxins18050204 2026
Predicting Algal Bloom Dynamics in Drinking Water Reservoirs Using High-Frequency In Situ Data and Machine Learning [0.03%]
基于高时间分辨率原位数据和机器学习预测饮用水水库的藻华动态
Jiangbin Wang,Min Jiang,Shuhua Wang et al.
Jiangbin Wang et al.
Algal proliferation in subtropical drinking water reservoirs has become increasingly severe, and developing a reliable prediction for algal abundance through high-frequency in situ data is essential for early risk warning and effective mana...
Azemiops feae (Fea's Viper) Envenoming: A Case Report and Review of the Literature [0.03%]
费氏短吻蝮蛇咬伤：病例报告及文献回顾
Zichen Qiao,Yong Tang,Qianshun Zhou et al.
Zichen Qiao et al.
Azemiops feae (Fea's viper) is a phylogenetically distinctive Asian viper with poorly defined medical significance, and human envenomations remain rarely reported in the English-language literature. We describe a new case of A. feae envenom...
The "Direct Structural Disruption" Hypothesis: Bacteroides fragilis Toxin as a Potentiating Cofactor in MASH Pathogenesis [0.03%]
“直接结构破坏”假说：脆弱拟杆菌毒素作为MASH发病机制的潜力协同因子
Ju-Eun Hong,Soonjae Hwang
Ju-Eun Hong
Metabolic dysfunction-associated steatohepatitis (MASH) is a complex, multifactorial disease heavily influenced by the gut-liver axis. While enterotoxigenic Bacteroides fragilis (ETBF) and its principal virulence factor, B. fragilis toxin (...
Co-Expression and Co-Purification Enable Manufacturing of a Six-Monoclonal Antibody Botulinum Antitoxin Cocktail [0.03%]
共表达和纯化生产六种单克隆抗体肉毒杆菌抗毒素鸡尾酒制品
Andrew Davis,Kamaljit Bajwa,Zachary Martinez et al.
Andrew Davis et al.
A highly potent antitoxin for botulinum neurotoxin (BoNT) serotypes A and B has been developed that comprises three monoclonal antibodies (mAbs) targeting BoNT/A and three targeting BoNT/B. These oligoclonal antibody combinations neutralize...