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Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
L Mastrantoni,F Camarda,C Parrillo et al. L Mastrantoni et al.
Background: The No Specific Molecular Profile (NSMP) subtype accounts for ∼30%-40% of endometrial cancer (EC), comprising a heterogeneous group of EC. Pa...
V Martelli,J Vidal,J Gibert et al. V Martelli et al.
Background: Circulating tumor DNA (ctDNA) variations predict tumor response to systemic treatment (so-called molecular response) earlier than radiological assessment. However, a standardized categorization of molecular re...
T Pascual,G Villacampa,M Oliveira et al. T Pascual et al.
Background: The SOLTI-1303-PATRICIA trial (NCT02448420) is a phase II study investigating palbociclib and trastuzumab, with or without endocrine therapy, in hormone receptor (HR)-positive/human epidermal growth factor rec...
H S Rugo,R M Layman,F Lynce et al. H S Rugo et al.
Background: All three cyclin-dependent kinase 4/6 inhibitors (CDK4/6i; palbociclib, ribociclib, and abemaciclib) plus aromatase inhibitor (AI) significantly prolonged progression-free survival (PFS) versus placebo plus AI...
A Pretta,V Nasca,F Marmorino et al. A Pretta et al.
Background: Early-onset colorectal cancer (EO-CRC, ≤50 years of age) exhibits unique clinical and biological characteristics when compared with average-onset CRC (AO-CRC), but its overall molecular profile is still not w...
E Vita,A Scala,A Vitale et al. E Vita et al.
Background: Fusion events involving neuregulin 1 (NRG1), a member of the pan-HER pathway, have been highlighted as a potential therapeutic target; however, little is known about the epidemiological distribution and the pr...