Integrating continuous flow reaction and work-up: chiral amine resolution, separation and purification using a novel coalescing filter system [0.03%]
连续流动反应与后处理的集成：采用新型分相过滤系统手性胺拆分、分离及纯化
Bethan M Rowley,Lisa A Thompson,Luke A Power et al.
Bethan M Rowley et al.
To maximize the benefits of a continuous flow reaction, a continuous work-up is also needed. Herein, we present a process design and novel equipment for a continuous amine resolution reaction, integrated with liquid-liquid (L-L) extraction,...
Monitoring and controlling zeolite synthesis via reactor-based solutions: a fed-batch strategy [0.03%]
基于反应器的溶液监测和控制分子筛合成：连续进料批次策略
Amirhossein Javdani,Gleb Ivanushkin,Aron Deneyer et al.
Amirhossein Javdani et al.
Most conventional zeolite synthesis takes place in closed batch autoclaves that cannot be monitored or controlled during the process. Moreover, the study of time-dependent parameters of the synthesis with the conventional "cooling-opening" ...
Kinetics of dehydrogenation of n-heptane over GaPt supported catalytically active liquid metal solutions (SCALMS) [0.03%]
镓铂合金加金属客体原子液态溶液催化剂正庚烷脱氢性能及反应机理研究
Oshin Sebastian,Asem Al-Shaibani,Nicola Taccardi et al.
Oshin Sebastian et al.
The concept of Supported Catalytically Active Liquid Metal Solutions (SCALMS) was explored for the catalytic dehydrogenation of n-heptane. For this purpose, a GaPt on alumina (Ga84Pt/Al2O3) was compared with a Pt on alumina catalyst at diff...
Microfluidic Localized Hydrogel Polymerization Enables Simultaneous Recording of Neural Activity and Behavior in C. elegans [0.03%]
微流控局部水凝胶聚合技术可同时记录秀丽隐杆线虫神经活动和行为反应
Hyun Jee Lee,Julia Vallier,Hang Lu
Hyun Jee Lee
Monitoring an animal's brain activity during motion provides a means to interpret the brain activity in the context of movement. However, it is challenging to obtain information about the animal's movement during neural imaging in the popul...
A robust data analytical method to investigate sequence dependence in flow-based peptide synthesis [0.03%]
一种稳健的用于研究基于流式的肽合成中序列依赖性的数据分析方法
Bálint Tamás,Pietro Luigi Willi,Héloïse Bürgisser et al.
Bálint Tamás et al.
Computer-assisted methods, which hold the promise to transform synthetic organic chemistry, are often limited by experimental data lacking in quality, diversity, and quantity. In solid-phase peptide synthesis (SPPS), automated flow chemistr...
A multistep (semi)-continuous biocatalytic setup for the production of polycaprolactone [0.03%]
用于生产聚己内酯的多步（半）连续生物催化装置
Alessia Valotta,Daniela Stelzer,Tamara Reiter et al.
Alessia Valotta et al.
Biocatalysis has gained increasing importance as an eco-friendly alternative for the production of bulk and fine chemicals. Within this paradigm, Baeyer Villiger monoxygenases (BVMOs) serve as enzymatic catalysts that provide a safe and sus...
Desulfurization of diesel via joint adsorption and extraction using a porous liquid derived from ZIF-8 and a phosphonium-type ionic liquid [0.03%]
基于ZIF-8和
Chenhua Shu,Min Zhao,Hua Cheng et al.
Chenhua Shu et al.
A type-III porous liquid based on zeolitic imidazolate framework-8 (ZIF-8) and an ionic liquid trihexyltetradecylphosphonium bis(trifluoromethylsulfonyl)imide ([THTDP][BTI]) was synthesized and used for the desulfurization of model diesel. ...
Deema Khunda,Sirui Li,Nikolay Cherkasov et al.
Deema Khunda et al.
A novel plate-to-plate dielectric barrier discharge microreactor (micro DBD) has been demonstrated in CO2 splitting. In this design, the ground electrode has a cooling microchannel to maintain the electrode temperature in the 263-298 K rang...
Process intensification of continuous-flow seATRP by a sonicated multi-reactor setup [0.03%]
基于超声波多反应器装置的连续流动技术强化原子转移自由基聚合过程
Suqi Zhang,Tanja Junkers,Simon Kuhn
Suqi Zhang
Simplified electrochemically mediated atom transfer radical polymerization (seATRP) is a versatile technique for synthesizing polymers with precise control and complex architecture. Continuous-flow seATRP has recently been realized by using...
Automated sulfur-[18F]fluoride exchange radiolabelling of a prostate specific membrane antigen (PSMA) targeted ligand using the GE FASTlab™ cassette-based platform [0.03%]
基于GE公司FASTlabTM磁带式模块的前列腺特异性膜抗原(PSMA)配体自动S-[18F]氟代合成方法
Zixuan Yang,Chris Barnes,Juozas Domarkas et al.
Zixuan Yang et al.
Sulfur-[18F]fluoride exchange radiochemistry is a rapid and convenient method for incorporating fluorine-18 into biologically active molecules. We report a fully automated radiolabelling procedure for the synthesis of a [18F]SO3F-bearing pr...