Alex Schudel,David M Francis,Susan N Thomas
Alex Schudel
A significant fraction of the total immune cells in the body are located in several hundred lymph nodes, in which lymphocyte accumulation, activation and proliferation are organized. Therefore, targeting lymph nodes provides the possibility...
Yongzhi Qiu,David R Myers,Wilbur A Lam
Yongzhi Qiu
Cells actively interact with their microenvironment, constantly sensing and modulating biochemical and biophysical signals. Blood comprises a variety of non-adherent cells that interact with each other and with endothelial and vascular smoo...
Andrea M Armani,Darrell E Hurt,Darryl Hwang et al.
Andrea M Armani et al.
A global effort is ongoing in the scientific community and in the maker movement, which focuses on creating devices and tinkering with them, to reverse-engineer commercial medical equipment and get it to healthcare workers. For these 'low-t...
Orad Reshef,Igor Aharonovich,Andrea M Armani et al.
Orad Reshef et al.
The first online-only meeting in photonics, held on 13 January 2020, was a resounding success, with 1100 researchers participating remotely to discuss the latest advances in photonics. Here, the organizers share their tips and advice on how...
Sungwoong Kim,Shivem B Shah,Pamela L Graney et al.
Sungwoong Kim et al.
Immunoengineering applies quantitative and materials-based approaches for the investigation of the immune system and for the development of therapeutic solutions for various diseases, such as infection, cancer, inflammatory diseases and age...
Yuanwen Jiang,Bozhi Tian
Yuanwen Jiang
Biological systems respond to and communicate through biophysical cues, such as electrical, thermal, mechanical and topographical signals. However, precise tools for introducing localized physical stimuli and/or for sensing biological respo...
Ritchie Chen,Andres Canales,Polina Anikeeva
Ritchie Chen
Within the mammalian nervous system, billions of neurons connected by quadrillions of synapses exchange electrical, chemical and mechanical signals. Disruptions to this network manifest as neurological or psychiatric conditions. Despite dec...
Biofabrication strategies for 3D in vitro models and regenerative medicine [0.03%]
用于体外三维模型和再生医学的生物制造策略
Lorenzo Moroni,Jason A Burdick,Christopher Highley et al.
Lorenzo Moroni et al.
Organs are complex systems composed of different cells, proteins and signalling molecules that are arranged in a highly ordered structure to orchestrate a myriad of functions in our body. Biofabrication strategies can be applied to engineer...
Pranjali Beri,Bibiana F Matte,Laurent Fattet et al.
Pranjali Beri et al.
The use of biomaterials has substantially contributed to both our understanding of tumorigenesis and our ability to identify and capture tumour cells in vitro and in vivo. Natural and synthetic biomaterials can be applied as models to recap...
Seung-Min Park,Amin Aalipour,Ophir Vermesh et al.
Seung-Min Park et al.
Nanodiagnostics as a field makes use of fundamental advances in nanobiotechnology to diagnose, characterize and manage disease at the molecular scale. As these strategies move closer to routine clinical use, a proper understanding of differ...