Sungwoong Kim,Shivem B Shah,Pamela L Graney et al.
Sungwoong Kim et al.
Immunoengineering applies quantitative and materials-based approaches for the investigation of the immune system and for the development of therapeutic solutions for various diseases, such as infection, cancer, inflammatory diseases and age...
Yuanwen Jiang,Bozhi Tian
Yuanwen Jiang
Biological systems respond to and communicate through biophysical cues, such as electrical, thermal, mechanical and topographical signals. However, precise tools for introducing localized physical stimuli and/or for sensing biological respo...
Ritchie Chen,Andres Canales,Polina Anikeeva
Ritchie Chen
Within the mammalian nervous system, billions of neurons connected by quadrillions of synapses exchange electrical, chemical and mechanical signals. Disruptions to this network manifest as neurological or psychiatric conditions. Despite dec...
Biofabrication strategies for 3D in vitro models and regenerative medicine [0.03%]
用于体外三维模型和再生医学的生物制造策略
Lorenzo Moroni,Jason A Burdick,Christopher Highley et al.
Lorenzo Moroni et al.
Organs are complex systems composed of different cells, proteins and signalling molecules that are arranged in a highly ordered structure to orchestrate a myriad of functions in our body. Biofabrication strategies can be applied to engineer...
Pranjali Beri,Bibiana F Matte,Laurent Fattet et al.
Pranjali Beri et al.
The use of biomaterials has substantially contributed to both our understanding of tumorigenesis and our ability to identify and capture tumour cells in vitro and in vivo. Natural and synthetic biomaterials can be applied as models to recap...
Seung-Min Park,Amin Aalipour,Ophir Vermesh et al.
Seung-Min Park et al.
Nanodiagnostics as a field makes use of fundamental advances in nanobiotechnology to diagnose, characterize and manage disease at the molecular scale. As these strategies move closer to routine clinical use, a proper understanding of differ...
Jianyu Li,David J Mooney
Jianyu Li
Hydrogel delivery systems can leverage therapeutically beneficial outcomes of drug delivery and have found clinical use. Hydrogels can provide spatial and temporal control over the release of various therapeutic agents, including small-mole...
The design of reversible hydrogels to capture extracellular matrix dynamics [0.03%]
可逆水凝胶的设计以捕获细胞外基质的动态变化
Adrianne M Rosales,Kristi S Anseth
Adrianne M Rosales
The extracellular matrix (ECM) is a dynamic environment that constantly provides physical and chemical cues to embedded cells. Much progress has been made in engineering hydrogels that can mimic the ECM, but hydrogel properties are, in gene...
Hongmin Chen,Weizhong Zhang,Guizhi Zhu et al.
Hongmin Chen et al.
Advances in nanoparticle synthesis and engineering have produced nanoscale agents affording both therapeutic and diagnostic functions that are often referred to by the portmanteau 'nanotheranostics'. The field is associated with many applic...
Twan Lammers,Fabian Kiessling,Marianne Ashford et al.
Twan Lammers et al.
Nanomedicine may have a delivery problem. Rigorous, realistic and holistic rethinking is needed to improve nanomedicine performance and increase patient benefit.