Gillie A Roth,Vittoria C T M Picece,Ben S Ou et al.
Gillie A Roth et al.
Vaccines are the key technology to combat existing and emerging infectious diseases. However, increasing the potency, quality and durability of the vaccine response remains a challenge. As our knowledge of the immune system deepens, it beco...
Christine Horejs
Christine Horejs
Lipid nanoparticles are essential to mRNA vaccines. The groundwork for lipid-based drug delivery systems was laid more than 40 years ago in the lab of Pieter Cullis, Professor at the University of British Columbia. Nature Reviews Materials ...
Adam J Gormley,Michael A Webb
Adam J Gormley
The design of new functional polymers depends on the successful navigation of their structure-function landscapes. Advances in combinatorial polymer chemistry and machine learning provide exciting opportunities for the engineering of fit-fo...
Xucheng Hou,Tal Zaks,Robert Langer et al.
Xucheng Hou et al.
Messenger RNA (mRNA) has emerged as a new category of therapeutic agent to prevent and treat various diseases. To function in vivo, mRNA requires safe, effective and stable delivery systems that protect the nucleic acid from degradation and...
Audrey K Bowden,Cullen R Buie
Audrey K Bowden
The experiences of Black scientists and engineers reveal that science is not a meritocracy. Here is a list of recommendations to combat anti-Black racism in academic institutions. ...
Zoë Ayres
Zoë Ayres
Good mental health and wellbeing of research staff and students lead to better science: it is time to reflect on what we can do as team leaders to create a positive research culture. ...
Christine Horejs
Christine Horejs
An article in Nature Communications reports a method for the rapid detection of SARS-CoV-2 in saliva samples using nanopores and a machine learning algorithm. ...
Shengjie Ling,David L Kaplan,Markus J Buehler
Shengjie Ling
Nanofibrillar materials, such as cellulose, chitin and silk, are highly ordered architectures, formed through the self-assembly of repetitive building blocks into higher-order structures, which are stabilized by non-covalent interactions. T...
Andrew C Daly,Lindsay Riley,Tatiana Segura et al.
Andrew C Daly et al.
Hydrogel microparticles (HMPs) are promising for biomedical applications, ranging from the therapeutic delivery of cells and drugs to the production of scaffolds for tissue repair and bioinks for 3D printing. Biologics (cells and drugs) can...
Sheng Tong,Buhle Moyo,Ciaran M Lee et al.
Sheng Tong et al.
Genome editing technologies, such as CRISPR/Cas9, are promising for treating otherwise incurable genetic diseases. Great progress has been made for ex vivo genome editing; however, major bottlenecks exist in the development of efficient, sa...