Hayden A Evans,Yue Wu,Ram Seshadri et al.
Hayden A Evans et al.
Materials with the perovskite ABX3 structure play a major role across materials chemistry and physics as a consequence of their ubiquity and wide range of useful properties. ReO3-type structures can be described as ABX3 perovskites in which...
Elizabeth Nance,Suzie H Pun,Rajiv Saigal et al.
Elizabeth Nance et al.
Despite the rising global incidence of central nervous system (CNS) disorders, CNS drug development remains challenging, with high costs, long pathways to clinical use and high failure rates. The CNS is highly protected by physiological bar...
Koushik Debnath,Kevin Las Heras,Ambar Rivera et al.
Koushik Debnath et al.
The extracellular matrix in microenvironments harbors a variety of signals to control cellular functions and the materiality of tissues. Most efforts to synthetically reconstitute the matrix by biomaterial design have focused on decoupling ...
Amy Em Beedle,Sergi Garcia-Manyes
Amy Em Beedle
In addition to biochemical signals and genetic considerations, mechanical forces are rapidly emerging as a master regulator of human physiology. Yet the molecular mechanisms that regulate force-induced functionalities across a wide range of...
Morteza Mahmoudi,Markita P Landry,Anna Moore et al.
Morteza Mahmoudi et al.
The protein corona spontaneously develops and evolves on the surface of nanoscale materials when they are exposed to biological environments, altering their physiochemical properties and affecting their subsequent interactions with biosyste...
Functionalizing DNA origami to investigate and interact with biological systems [0.03%]
功能化DNA折纸结构以研究和与生物系统相互作用
Grant A Knappe,Eike-Christian Wamhoff,Mark Bathe
Grant A Knappe
DNA origami has emerged as a powerful method to generate DNA nanostructures with dynamic properties and nanoscale control. These nanostructures enable complex biophysical studies and the fabrication of next-generation therapeutic devices. F...
Danielle M Fitzgerald,Yolonda L Colson,Mark W Grinstaff
Danielle M Fitzgerald
Pressure sensitive adhesives are familiar household items spanning applications in everyday repair, office supplies, and topical wound care. Through innovations in material and polymer science, pressure sensitive adhesives will advance from...
Erika Moore,Josephine B Allen,Connie J Mulligan et al.
Erika Moore et al.
Bioengineered platforms, intended to be used in the investigation of human health and disease, often incorporate cells of unknown ancestry or that lack diversity. To develop tools and platforms that benefit the entire human population, we m...
Choongseok Chang,Volker L Deringer,Kalpana S Katti et al.
Choongseok Chang et al.
Exascale computers - supercomputers that can perform 1018 floating point operations per second - started coming online in 2022: in the United States, Frontier launched as the first public exascale supercomputer and Aurora is due to open soo...
Passive, active and endogenous organ-targeted lipid and polymer nanoparticles for delivery of genetic drugs [0.03%]
遗传药物的被动、主动和内源性器官靶向脂质及聚合物纳米粒给药系统
Sean A Dilliard,Daniel J Siegwart
Sean A Dilliard
Genetic drugs based on nucleic acid biomolecules are a rapidly emerging class of medicines that directly reprogramme the central dogma of biology to prevent and treat disease. However, multiple biological barriers normally impede the intrac...