Revisiting Transvenous Phrenic Nerve Stimulation in Central Sleep Apnoea and Heart Failure: Emerging Innovations in Clinical Trials Analysis [0.03%]
中心性睡眠呼吸暂停和心力衰竭中食管神经刺激的再评价：临床试验分析中的新兴创新技术
Tarek Bekfani,Joseph D Abraham,William T Abraham
Tarek Bekfani
Central sleep apnoea (CSA) is a common comorbidity in patients with heart failure. Due to its insidious and chronic nature, CSA often remains unrecognised. Patients with CSA typically present with symptoms, such as daytime fatigue, recurren...
The Emerging Role of Aldosterone Synthase Inhibitors in Overcoming Renin-Angiotensin-Aldosterone System Therapy Limitations: A Narrative Review [0.03%]
醛固酮合酶抑制剂在克服肾素血管紧张素醛固酮系统治疗局限性方面的新兴作用：叙述性综述
Shubh K Patel,Hwee Teoh,Ahreni Saunthar et al.
Shubh K Patel et al.
The renin-angiotensin-aldosterone system is integral to cardiorenal health, with aldosterone controlling fluid balance, blood pressure and cardiac remodelling. Despite the widespread use of angiotensin-converting enzyme inhibitors, angioten...
Understanding the Role of Glucagon-like Peptide-1 Receptor Agonists in the Treatment of Heart Failure [0.03%]
理解肠促胰素-1受体激动剂治疗心力衰竭的作用机制
Giovanni Battista Bonfioli,Matteo Pagnesi,Daniela Tomasoni et al.
Giovanni Battista Bonfioli et al.
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), initially developed for glycaemic control in patients with type 2 diabetes, have demonstrated significant cardiometabolic benefits beyond glucose regulation. These agents have multiple ...
Addressing Endothelial Dysfunction in Heart Failure: The Role of Endothelial Progenitor Cells and New Treatment Horizons [0.03%]
心力衰竭中内皮功能障碍的治疗：内皮祖细胞及新的治疗策略的作用
Eugenio Carulli,Marialuisa Sveva Marozzi,Maria Cristina Carella et al.
Eugenio Carulli et al.
Heart failure (HF) is closely linked to endothelial dysfunction, which contributes significantly to its progression. Endothelial dysfunction in HF is marked by reduced nitric oxide bioavailability, increased oxidative stress and inflammatio...
Vijay Chopra
Vijay Chopra
Pharmacological Therapy of HFrEF in 2025: Navigating New Advances and Old Unmet Needs in An Eternal Balance Between Progress and Perplexities [0.03%]
2025年射血分数降低的心力衰竭药物治疗：在进步与困惑之间的永恒平衡中探索新的进展和旧的未满足需求
Massimo Mapelli,Filippo Maria Rubbo,Simona Costantino et al.
Massimo Mapelli et al.
Recent advances in medical therapy have significantly improved the prognosis of patients with heart failure and reduced ejection fraction (HFrEF). The established four pillars of HFrEF treatment - β-blockers, angiotensin-converting enzyme ...
Heart Failure Management in Cardiac Amyloidosis: Towards a Paradigm Shift [0.03%]
心脏淀粉样变性的心力衰竭管理：一场范式的转变
Giorgia Panichella,Alberto Aimo,Vincenzo Castiglione et al.
Giorgia Panichella et al.
Heart failure (HF) and cardiac amyloidosis (CA) are significant clinical challenges, with evolving epidemiological patterns reshaping the understanding of these conditions. Traditionally linked with HF with preserved ejection fraction, CA i...
Improving the Management of Patients with Heart Failure with Reduced Ejection Fraction in Clinical Practice: The Case for Angiotensin Receptor-Neprilysin Inhibitor [0.03%]
改善射血分数降低的心力衰竭患者的临床管理——血管紧张素受体-中性肽酶抑制剂的应用案例分析
Massimo Iacoviello,Filippo Maria Sarullo,Claudio Bilato et al.
Massimo Iacoviello et al.
The high risk of adverse outcomes in patients with heart failure with reduced ejection fraction (HFrEF) demands urgent efforts in the initiation of guideline-directed medical therapy to reduce morbidity and mortality. Angiotensin receptor-n...
The Timing for Primary Prevention for ICD in the Current Era of Pharmacotherapy [0.03%]
当前药物治疗时代的ICD一级预防时机选择
Anastasia Shchendrygina,Amin Yehya,Hadi Skouri
Anastasia Shchendrygina
Recent advances in the pharmacological therapy of heart failure with reduced ejection fraction (HFrEF) have significantly impacted the overall survival, heart failure hospitalisations and rates of sudden cardiac death (SCD). In this context...
Comparison of Landiolol and Esmolol on Haemodynamic Responses During Weaning of Intensive Care Unit Patients with Reduced Ejection Fraction after Vascular Surgery [0.03%]
用于血管手术后射血分数降低的重症监护患者的撤机过程中对心脏动力学反应的Landiolol和Esmolol比较研究
Georgios Koukoulitsios,Kyriaki Tsikritsaki,Georgios Magklaras et al.
Georgios Koukoulitsios et al.
Background: Weaning and tracheal extubation of patients after vascular surgery is a stressful procedure that triggers the sympathetic nervous system, potentially leading to deterioration of cardiac performance in patients...