Effects of dexrazoxane on doxorubicin-related cardiotoxicity and second malignant neoplasms in children with osteosarcoma: a report from the Children's Oncology Group [0.03%]
地塞瑞克对儿童骨肉瘤患病期间阿霉素引起的心脏毒性和继发性恶性肿瘤的影响：来自儿童肿瘤学组的报道
Lisa M Kopp,Richard B Womer,Cindy L Schwartz et al.
Lisa M Kopp et al.
Background: Dexrazoxane protects from lower-cumulative-dose doxorubicin cardiotoxicity, but the effect of dexrazoxane in children with sarcoma treated with higher-cumulative-dose doxorubicin is unknown. ...
Cardiotoxicity after cancer treatment: a process map of the patient treatment journey [0.03%]
癌症治疗后的 cardiotoxicity：患者治疗过程图
Robyn A Clark,Tania S Marin,Alexandra L McCarthy et al.
Robyn A Clark et al.
Background/aim: Cardiotoxicity is a potential complication of anticancer therapy. While guidelines have been developed to assist practitioners, an effective, evidence based clinical pathway for the treatment of cardiotoxi...
5-FU induced cardiotoxicity: case series and review of the literature [0.03%]
5-氟尿嘧啶引起的心脏毒性：病例系列和文献回顾
Cai Yuan,Hiral Parekh,Carmen Allegra et al.
Cai Yuan et al.
Background: 5-Fluorouracil (5-FU) is an antimetabolite chemotherapy used for a variety of solid tumors. It has the potential to cause a wide spectrum of cardiotoxicity, ranging from asymptomatic electrocardiographic chang...
An international survey of healthcare providers' knowledge of cardiac complications of cancer treatments [0.03%]
一项关于癌症治疗心脏并发症的国际医护知识调查
J Peng,M Rushton,C Johnson et al.
J Peng et al.
Background: Cardio-oncology is a young sub-specialty that addresses the needs of cancer patients at risk of, or who have experienced cancer therapy related cardiac dysfunction (CTRCD). This study assessed clinicians' unde...
Early markers of cardiovascular injury in childhood leukaemia survivors treated with anthracycline chemotherapy [0.03%]
接受蒽环类化疗的儿童急性淋巴细胞白血病幸存者的心血管损伤早期标志物筛查
Treya M Long,Channa E Marsh,Lawrence G Dembo et al.
Treya M Long et al.
Background: Cardiovascular disease (CVD) is the leading non-malignant cause of death in childhood cancer survivors. Heightened risk of CVD is often attributable to treatment with anthracycline chemotherapy. Anthracycline-...
Electrocardiograms for cardiomyopathy risk stratification in children with anthracycline exposure [0.03%]
儿童蒽环类药物暴露的心肌病风险分层的电生理指标检测
Lajja Desai,Lauren Balmert,Jennifer Reichek et al.
Lajja Desai et al.
Background: Early recognition of anthracycline-induced cardiomyopathy may reduce morbidity and mortality in children, but risk stratification tools are lacking. This study evaluates whether electrocardiogram (ECG) changes...
Concomitant use of renin-angiotensin-aldosterone system inhibitors prevent trastuzumab-induced cardiotoxicity in HER2+ breast cancer patients: an institutional retrospective study [0.03%]
联合使用肾素血管紧张素醛固酮系统抑制剂可预防HER2阳性乳腺癌患者曲妥珠单抗引起的心脏毒性：机构回顾性研究
Melissa Y Y Moey,Darla K Liles,Blase A Carabello
Melissa Y Y Moey
Background: Cardiotoxicity is an adverse effect of trastuzumab (TRA) in the treatment of human epidermal growth factor 2 positive (HER2+) breast cancer. Current literature on the cardioprotective effects of agents targete...
Aakash Desai,Arish Noor,Saurabh Joshi et al.
Aakash Desai et al.
Background: Cancer is a chronic condition that induces significant emotional and physical stress, which may increase the risk for developing Takotsubo cardiomyopathy (TCM). ...
Spontaneously occurring cardiovascular lesions in commonly used laboratory animals [0.03%]
实验动物心血管疾病模型的自发产生及利用
Eugene Herman,Sandy Eldridge
Eugene Herman
The search for new chemical entities which are clinically effective and do not adversely affect the cardiovascular system is an ongoing objective. In vivo studies designed to detect potential drug-induced cardiovascular toxicity typically u...
A quality improvement approach to reducing hospital readmissions in patients with cancer and heart failure [0.03%]
改善癌症和心力衰竭患者住院再入院的质量改进方法
Anecita Fadol,Joylynmae Estrella,Valerie Shelton et al.
Anecita Fadol et al.
Background: The management of patients with cancer and concurrent heart failure (HF) is challenging. The increased complexity of treatment and the occurrence of multiple overlapping symptoms may lead to frequent hospital ...