The interplay between genetic background and sexual dimorphism of doxorubicin-induced cardiotoxicity [0.03%]
遗传背景与多柔比星诱导的心脏毒性间的性别差异及其相互作用机制研究
Beshay N Zordoky,M Judith Radin,Lois Heller et al.
Beshay N Zordoky et al.
Background: Doxorubicin (DOX) is a very effective anticancer medication that is commonly used to treat hematological malignancies and solid tumors. Nevertheless, DOX is known to have cardiotoxic effects that may lead to c...
Crizotinib Inhibits Hyperpolarization-activated Cyclic Nucleotide-Gated Channel 4 Activity [0.03%]
克唑替尼通过抑制HCN4通道活性发挥抗心律失常作用
Zhushan Zhang,Tai-Qin Huang,Igor Nepliouev et al.
Zhushan Zhang et al.
Background: Sinus bradycardia is frequently observed in patients treated with crizotinib, a receptor tyrosine kinase inhibitor used for the treatment of anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung canc...
Breast cancer treatment-associated cardiovascular toxicity and effects of exercise countermeasures [0.03%]
乳腺癌治疗相关的心血管毒副反应及运动干预效应
Anthony F Yu,Lee W Jones
Anthony F Yu
Advances in breast cancer treatment have improved disease-free survival and overall survival in women with early-stage breast cancer. However, these improvements may be attenuated by the adverse cardiovascular effects associated with breast...
Exercise and cardiovascular health among breast cancer survivors: a scoping review of current observational evidence [0.03%]
乳腺癌幸存者运动与心血管健康：当前观察证据的范围审查
Background: Breast cancer survivors are at increased risk of cardiovascular events due to the cardiotoxic effects of cancer treatment. Exercise participation can lower the risk of various adverse cardiovascular health out...