Management strategies and clinical outcomes in breast cancer patients who develop left ventricular dysfunction during trastuzumab therapy [0.03%]
曲妥珠单抗治疗过程中发生左心室功能不全的乳腺癌患者的管理策略和临床结局
Ren Jie Robert Yao,Jordan Gibson,Christine Simmons et al.
Ren Jie Robert Yao et al.
Background: Trastuzumab reduces risk of breast cancer recurrence but carries risk of cardiotoxicity that may be reversible upon treatment cessation and institution of left ventricular (LV) enhancement therapies (LVETx). W...
Insurance disparity in cardiovascular mortality among non-elderly cancer survivors [0.03%]
非老年癌症幸存者心血管疾病死亡率的保险差异性分析
Tiantian Shi,Changchuan Jiang,Cenjing Zhu et al.
Tiantian Shi et al.
Background: Insurance status plays a vital role in cancer diagnosis, treatments and survival. Cancer patients have higher cardiovascular disease (CVD) mortality than the general population. ...
Newly diagnosed cardiovascular disease in patients treated with immune checkpoint inhibitors: a retrospective analysis of patients at an academic tertiary care center [0.03%]
免疫检查点抑制剂治疗患者的新发心血管疾病:学术三级护理中心患者的回顾性分析
Nida Waheed,Michael G Fradley,David L DeRemer et al.
Nida Waheed et al.
Background: Immune checkpoint inhibitors (ICIs) are a novel class of anticancer agents that have demonstrated clinical response for both solid and hematological malignancies. ICIs are associated with development of immune...
Risk of malignancy long after acute coronary syndrome in selected urban and rural areas and comparison with smoking risk: the ABC-7* study on Heart Disease [0.03%]
城市和农村地区急性冠脉综合征后远期患癌风险研究及与吸烟风险的对比:ABC-7 * 心脏病项目研究报告
Giuseppe Berton,Heba T Mahmoud,Rosa Palmieri et al.
Giuseppe Berton et al.
Background: Increased cancer risk has been reported in patients with acute coronary syndrome (ACS). Objectives: To investigate geograph...
Competing mortality risks: predicted cardiovascular disease risk versus predicted risk of breast cancer mortality in patients receiving adjuvant chemotherapy in a single Irish center [0.03%]
竞争性死亡风险:单一爱尔兰中心接受新辅助化疗患者的预测心血管疾病风险与预测乳腺癌死亡风险的比较
Lisa Prior,Hannah Featherstone,David OReilly et al.
Lisa Prior et al.
Background: Due to advances in care, most women diagnosed with breast cancer do not die from the disease itself. Instead, cardiovascular disease (CVD) remains the most frequent cause of death. Many breast cancer patients ...
High intensity exercise during breast cancer chemotherapy - effects on long-term myocardial damage and physical capacity - data from the OptiTrain RCT [0.03%]
高强度锻炼对乳腺癌化疗患者长期心脏损伤和体能状况的影响——来自OptiTrain随机对照试验的数据分析
Josefin Ansund,Sara Mijwel,Kate A Bolam et al.
Josefin Ansund et al.
Background: Adjuvant systemic breast cancer treatment improves disease specific outcomes, but also presents with cardiac toxicity. In this post-hoc exploratory analysis of the OptiTrain trial, the effects of exercise on c...
Plasma proteome profiling of cardiotoxicity in patients with diffuse large B-cell lymphoma [0.03%]
弥漫性大B细胞淋巴瘤患者心毒性血浆蛋白组学分析
Charlott Mörth,Amal Abu Sabaa,Eva Freyhult et al.
Charlott Mörth et al.
Background: Cardiovascular toxicity is a notorious complication of doxorubicin (DXR) therapy for diffuse large B-cell lymphoma (DLBCL). Although surveillance of well-known biological markers for cardiovascular disease (CV...
Echocardiographic myocardial strain analysis describes subclinical cardiac dysfunction after craniospinal irradiation in pediatric and young adult patients with central nervous system tumors [0.03%]
颅脊部照射后儿童和青年人中枢神经系统肿瘤患者的亚临床心脏功能障碍的超声心动图心肌应变分析描述
Hugo R Martinez,Ralph Salloum,Erin Wright et al.
Hugo R Martinez et al.
Background: Craniospinal irradiation (CSI) is part of the treatment of central nervous system (CNS) tumors and is associated with cardiovascular disease in adults. Global myocardial strain analysis including longitudinal ...
Hypertension in cancer patients treated with anti-angiogenic based regimens [0.03%]
抗血管生成为基础的治疗方案所致癌症患者的高血压
Yishay Wasserstrum,Ran Kornowski,Pia Raanani et al.
Yishay Wasserstrum et al.
New anti-cancer drugs that inhibit the vascular endothelial growth factor (VEGF) signaling pathway are highly effective in the treatment of solid tumors, however concerns remain regarding their cardiovascular safety. The most common side ef...
Mark P Little,Steven E Lipshultz
Mark P Little
Exposure to high doses of ionizing radiation is associated with damage to the heart and coronary arteries. However, only recently have studies with high-quality individual dosimetry data allowed this risk to be estimated while adjusting for...