Current treatment strategies for patients with advanced gastroenteropancreatic neuroendocrine tumors (GEP-NETs) [0.03%]
胃肠道胰神经内分泌肿瘤(GEP-NETs)的当前治疗策略
Inbal Uri,Simona Grozinsky-Glasberg
Inbal Uri
Background: Neuroendocrine tumors (NETs) are rare neoplasms, with an estimated annual incidence of ~ 6.9/100,000. NETs arise throughout the body from cells of the diffuse endocrine system. More than half originate from en...
Pheochromocytoma and Paraganglioma in Neurofibromatosis type 1: frequent surgeries and cardiovascular crises indicate the need for screening [0.03%]
神经纤维瘤病1型的嗜铬细胞瘤和副节瘤：频繁手术和心血管危象提示需要进行筛查
Elisabeth Joye Petr,Tobias Else
Elisabeth Joye Petr
Background: Pheochromocytomas and Paragangliomas (PCC/PGL) are rare endocrine tumors that are mostly benign, but often hormone producing, causing significant morbidity and mortality due to excess catecholamine secretion a...
Weight loss and bone mineral density in obese adults: a longitudinal analysis of the influence of very low energy diets [0.03%]
体重减轻与骨密度：非常低热量饮食对肥胖成年人的影响分析
Palak Choksi,Amy Rothberg,Andrew Kraftson et al.
Palak Choksi et al.
Background: The long-term effect of weight reduction on skeletal health is not well understood. The purpose of this study was to examine the impact of an intensive medical weight loss intervention using very low energy di...
Rare Clinical Entity: Metastatic malignant struma ovarii diagnosed during pregnancy - Lessons for management [0.03%]
罕见临床病例：妊娠期卵巢甲状腺肿恶性转移的诊断与治疗经验
Corey J Lager,Ronald J Koenig,Richard W Lieberman et al.
Corey J Lager et al.
Background: Malignant struma ovarii is an ovarian teratoma containing at least 50% thyroid tissue which has the potential to metastasize and produce thyroid hormone. Given its rarity, management strategies are not well-es...
The challenges of diagnosing osteoporosis and the limitations of currently available tools [0.03%]
骨质疏松症的诊断难题及现有工具的局限性
Palak Choksi,Karl J Jepsen,Gregory A Clines
Palak Choksi
Dual-energy X-ray absorptiometry (DXA) was the first imaging tool widely utilized by clinicians to assess fracture risk, especially in postmenopausal women. The development of DXA nearly coincided with the availability of effective osteopor...
Liraglutide and Dulaglutide therapy in addition to SGLT-2 inhibitor and metformin treatment in Indian type 2 diabetics: a real world retrospective observational study [0.03%]
利拉鲁肽和杜拉鲁肽联合钠葡萄糖协同转运蛋白-2抑制剂和二甲双胍治疗印度2型糖尿病患者：一项真实世界回顾性观察研究
S Ghosal,B Sinha
S Ghosal
Background: Therapy for Type 2 diabetes (T2D) has been transformed by the introduction of newer agents like Glucagon like Peptide Receptor Agonists (GLP-1RA) and Sodium-glucose linked transporter inhibitors (SGLT2i). Howe...
Characteristics of insulin-Naïve people with type 2 diabetes who successfully respond to insulin glargine U100 after 24 weeks of treatment: a meta-analysis of individual participant data from 3 randomized clinical trials [0.03%]
初发2型糖尿病患者使用甘精胰岛素U100治疗24周后成功获益的临床特征：三项随机临床试验个体参与者数据Meta分析
M H Cummings,D Cao,I Hadjiyianni et al.
M H Cummings et al.
Background: To identify baseline/clinical characteristics associated with clinically meaningful responses to insulin glargine 100 U/mL (IGlar) in insulin-naive people with type 2 diabetes mellitus (T2DM). ...
Diabetes mellitus and bone health: epidemiology, etiology and implications for fracture risk stratification [0.03%]
糖尿病与骨骼健康：流行病学、病因及骨折风险分层的含义
Rodrigo J Valderrábano,Maria I Linares
Rodrigo J Valderrábano
Skeletal fractures can result when there are co-morbid conditions that negatively impact bone strength. Fractures represent an important source of morbidity and mortality, especially in older populations. Diabetes mellitus is a metabolic di...
Insulin therapy for type 2 diabetes - are we there yet? The d-Nav® story [0.03%]
胰岛素治疗2型糖尿病了吗？d-Nav®胰岛素治疗系统研究故事
I Hodish
I Hodish
Insulin replacement therapy is mostly used by patients with type 2 diabetes who become insulin deficient and have failed other therapeutic options. They comprise about a quarter of those with diabetes, endures the majority of the complicati...
Patterns of physical activity in sedentary older individuals with type 2 diabetes [0.03%]
久坐型2型糖尿病老年人的体力活动模式
Pearl G Lee,Jinkyung Ha,Caroline S Blaum et al.
Pearl G Lee et al.
Background: The Community Healthy Activities Model Program for Seniors (CHAMPS) survey, summarized into weekly caloric expenditures, is a common physical activity (PA) assessment tool among older adults. Specific types of...