Implementing SGLT2 Inhibitors in Cardiovascular-Kidney-Metabolic (CKM) Syndrome: A Multidisciplinary Expert Perspective [0.03%]
从多学科专家视角看SGLT2抑制剂在心血管-肾脏-代谢(CKM)综合征中的应用
Angelo Avogaro,Mauro Gori,Giuseppe Grandaliano et al.
Angelo Avogaro et al.
Aims: Cardiovascular-kidney-metabolic (CKM) syndrome defines a pathophysiological continuum driven by reciprocal dysfunction across the cardiovascular, renal and metabolic systems. Although sodium-glucose co-transporter 2...
Juan Tamargo,Stefan Agewall,Giuseppe Ambrosio et al.
Juan Tamargo et al.
Despite recent advances in cardiovascular pharmacotherapy, prevention and treatment of many cardiovascular diseases remain limited with a clear need for more effective and safer pharmacological strategies. Here, we summarize the most releva...
Heart Failure and Tricuspid Regurgitation: The Role of SGLT2 Inhibitors in Improving Outcomes [0.03%]
心力衰竭和三尖瓣反流:钠葡萄糖协同转运蛋白2抑制剂改善预后的机制
Ranel Loutati,Viana Copeland,Shir Elimeleh et al.
Ranel Loutati et al.
Aims: Sodium-glucose cotransporter-2 inhibitors (SGLT2i) have transformed heart failure (HF) management, yet their effect in patients with concomitant tricuspid regurgitation (TR) remains unclear. We evaluated the associa...
Antonin Trimaille,Taraneh Tatarcheh,Amandine Granier et al.
Antonin Trimaille et al.
Cardiotoxicity in Dual Immune Checkpoint Inhibitors: A Critical Appraisal of Signal Interpretation and Future Directions [0.03%]
双重免疫检查点抑制剂引起的心脏毒性:信号解释和未来研究方向的批判性评价
Weikai Dong,Qifeng Song,Qiang Wang
Weikai Dong
Targeted Anticoagulant Reversal, Unintended Consequences: Lessons From Andexanet Alfa [0.03%]
靶向抗凝逆转的意外后果——来自Andexanet α 阿法的例子分析
Jerrold H Levy,Joseph R Shaw
Jerrold H Levy
Christian Funck-Brentano,Ghislaine Filliatreau
Christian Funck-Brentano
A farewell to professor Stefan Agewall from the ESC Working Group on Cardiovascular Pharmacotherapy [0.03%]
致心血管药理学工作组名誉主席Stefan Agewall教授
Dobromir Dobrev,Juan-Carlos Kaski,Bianca Rocca et al.
Dobromir Dobrev et al.
Impact of single versus dual local anaesthetic regimen on the efficacy and safety of percutaneous stellate ganglion block for electrical storm: new insights from the STAR study [0.03%]
一项关于单用局麻药与双联局部麻醉方案对经皮星状交感神经阻滞治疗电风暴疗效和安全性影响的研究:STAR研究的新启示
Alessia Currao,Veronica Dusi,Matteo Casula et al.
Alessia Currao et al.
Aims: Percutaneous stellate ganglion block (PSGB) is a promising treatment for refractory electrical storm (ES). However, there is a lack of solid indications regarding the optimal pharmacological regimens and combination...
A Bayesian analysis of finerenone in heart failure with mildly reduced and preserved ejection fraction: a pre-specified analysis of FINEARTS-HF [0.03%]
一种巴瑞肾素在轻度收缩功能减退和保留的心力衰竭中的贝叶斯分析:FINEARTS-HF预设分析
Alasdair D Henderson,Kieran F Docherty,Atefeh Talebi et al.
Alasdair D Henderson et al.
Background: The non-steroidal mineralocorticoid receptor agonist (MRA) finerenone, reduced heart failure events and cardiovascular death in patients with heart failure with mildly reduced or preserved ejection fraction (H...