Understanding and addressing the obstacles to a trial of face masks in schools: a mixed-methods feasibility study [0.03%]
理解并解决在学校进行佩戴面罩试验的障碍：一项混合方法可行性研究
Ru Jia,Sophie Carlisle,Adam W A Geraghty et al.
Ru Jia et al.
Background: Face masks are a commonly used public health measure to control the spread of airborne infections, including in school-aged children. However, no trial of their effectiveness has been conducted in school setti...
Feasibility and acceptability of a novel substance use prevention intervention [0.03%]
一项新型物质使用预防干预措施的有效性和可接受性研究
Terrinieka W Powell,Bianca Smith,Wubishet Taye
Terrinieka W Powell
Background: Youth exposed to household challenges are among the groups most vulnerable to early substance use. To address the needs of this group, this pilot study assessed the feasibility of participant recruitment and r...
Protocol for a feasibility study, without control group, of a combined treatment for PTSD and difficulties in emotion regulation for patients with substance use disorder [0.03%]
物质使用障碍患者合并创伤后应激障碍和情绪调节困难的联合治疗可行性研究方案(无对照组)
Johanna Vigfusdottir,Edvard Breivik,Erlend Mork et al.
Johanna Vigfusdottir et al.
Background: There are high rates of co-occurring post-traumatic stress disorder (PTSD) among patients in treatment for substance use disorder (SUD). PTSD and SUD should be treated simultaneously, which is rarely the case....
Examining predictors of scale-up penalty in preliminary studies of health behavior interventions and subsequent larger trials: a meta-epidemiological review of diverse fields [0.03%]
系统评价和-meta分析：来自健康行为干预初步研究的规模扩大惩罚预测因素及后续大规模试验的综合回顾性评价
Lauren von Klinggraeff,Christopher D Pfledderer,Sarah Burkart et al.
Lauren von Klinggraeff et al.
Background: Scale-up penalty, a common phenomenon in which the promising effects found in early preliminary studies are substantially reduced when evaluated in a subsequent larger trial, can stall the advancement of healt...
Just in Time Adaptive Interventions for Behavioral Activation in Patients with Depression (JADE): protocol of a design, feasibility and preliminary effectiveness study [0.03%]
针对抑郁症患者的及时行为激活干预（JADE）方案：设计、可行性及初步效果研究的协议
Farid Chakhssi,Chani Nuij,Nadine Köhle et al.
Farid Chakhssi et al.
Background: Depression is a major public health problem with a rising prevalence and a negative impact on quality of life, mortality, and morbidity. While effective treatments, such as behavioral activation, are available...
Nephron Sparing Treatment (NEST) for small renal masses: understanding patients' and clinicians' experiences of a cohort-embedded randomised control trial [0.03%]
小肾病灶的保肾治疗（NEST研究）——理解患者和临床医生在此嵌套随机试验中的感受
Veronica Ranieri,Hannah Warren,Joana B Neves et al.
Veronica Ranieri et al.
Background: To understand the perspectives and experiences of patients and healthcare professionals regarding the trial design, recruitment and randomisation process to a novel cohort-embedded RCT design for Nephron Spari...
Identifying biomarkers of neurodevelopmental and mental health outcomes in a prospective longitudinal cohort of South African children: design and feasibility of the Safe Passage BONO study [0.03%]
南非儿童神经发育和心理健康结果生物标志物鉴定：前瞻性纵向队列研究的设计与可行性——安全通过-波诺研究
Priscilla E Springer,Lucy T Brink,Mandy Potter et al.
Priscilla E Springer et al.
Background: Early adversities before and after birth can impact children's cognitive and socioemotional development by altering critical brain maturational and functional processes. Some of these processes may be linked t...
Feasibility of early interval training in patients recovering from heart valve surgery due to infective endocarditis [0.03%]
早期间歇训练用于感染性心内膜炎心脏瓣膜手术后患者的可行性研究
Margrethe Müller,Tove Aminda Hanssen,David Johansen et al.
Margrethe Müller et al.
Background: Infective endocarditis is an infectious heart disease strongly associated with morbidity and mortality. Up to half of the patients with infective endocarditis require heart valve surgery. While early exercise-...
Implementation of a Mental Health Literacy e-Curriculum (MHLeC) in Malawi Universities: a feasibility cluster randomised trial protocol [0.03%]
马拉维大学心理健康素养电子课程（MHLeC）实施性集群随机试验方案：在马拉维大学实施心理健康素养电子课程（MHLeC）的可行性集群随机试验方案
Gloria Chirwa,Beatrice Chitalah,Joel Nyali et al.
Gloria Chirwa et al.
Background: Mental health literacy (MHL) in Malawi is low. Mental illness is often attributed to substance abuse or spirit possession, resulting in stigma, maltreatment, and discrimination towards people with mental healt...
Recruitment for a digitally based follow-up program for people with chronic obstructive pulmonary disease: a pilot cluster randomized controlled trial [0.03%]
慢性阻塞性肺疾病患者数字随访计划的招募：一项试点群随机对照试验
Haakon Kristian Kvidaland,Marjolein Memelink Iversen,Bente Frisk et al.
Haakon Kristian Kvidaland et al.
Background: Recruiting participants for clinical trials in primary care settings remains challenging, not least for interventions targeting individuals with chronic obstructive pulmonary disease (COPD). Clinical outcomes ...