Hannah M C Schreier,Edith Chen,Gregory E Miller
Hannah M C Schreier
Background: Child maltreatment is a common problem with known adverse consequences, yet its contributions to the development and course of pediatric asthma are only poorly understood. ...
CXC chemokine superfamily induced by Interferon-γ in asthma: a cross-sectional observational study [0.03%]
干扰素-γ诱导的慢性阻塞性肺疾病患者哮喘型趋化因子亚组的横断面研究
Yotaro Takaku,Tomoyuki Soma,Yoshitaka Uchida et al.
Yotaro Takaku et al.
Background: Asthma is a disease encompassing a variety of contributing factors. Phenotyping of asthma based on the profile of accumulated granulocytes in the airways has been performed to explore the mediators involved in...
Jose A Castro-Rodriguez,Adnan Custovic,Francine M Ducharme
Jose A Castro-Rodriguez
In the present review, we focus on evidence-based data for the use of inhaled corticosteroids (ICS), leukotriene receptor antagonist (LTRA), long-acting beta2-agonits (LABA) and oral corticosteroids (OCS), with a special emphasis on well-pe...
Once-daily fluticasone furoate/vilanterol versus twice daily combination therapies in asthma-mixed treatment comparisons of clinical efficacy [0.03%]
氟替卡松福莫特罗粉吸入剂单次给药与两次给药联合疗法治疗哮喘的混合治疗比较临床疗效分析
Henrik Svedsater,Gillian Stynes,Jaro Wex et al.
Henrik Svedsater et al.
Background: Fluticasone furoate (FF)/vilanterol (VI) is a once-daily inhaled corticosteroid (ICS)/long-acting beta2 agonist (LABA) combination. FF/VI, 92/22mcg and 184/22mcg, are approved in Europe as maintenance therapy ...
Asthma in the elderly patient [0.03%]
老年患者的哮喘
Louis-Philippe Boulet
Louis-Philippe Boulet
Asthma affects a significant proportion of elderly patients, but unfortunately, it is responsible for a high asthma-related morbidity and mortality in this population. This may be related not only to the development of a more severe asthma ...
Alida Benfante,Nicola Scichilone
Alida Benfante
Historically, asthma has been envisioned as a disease of younger ages. This has led to the assumption that respiratory symptoms suggestive of asthma occurring in older ages are to be attributed to conditions other than asthma, mainly COPD. ...
Higher serum levels of periostin and the risk of exacerbations in moderate asthmatics [0.03%]
中至重度哮喘患者periostin水平升高与急性加重的关系
N Scichilone,C Crimi,A Benfante et al.
N Scichilone et al.
Background: In asthma, exacerbations and poor disease control are linked to airway allergic inflammation. Serum periostin has been proposed as a systemic biomarker of eosinophilic inflammation. This pilot study aims at ev...
The WEB-based Asthma Control: an intriguing connection or a dangerous hazard? [0.03%]
基于网络的哮喘控制：有趣的联系还是危险的因素？
Carlo Lombardi,Giovanni Passalacqua,Giorgio Walter Canonica
Carlo Lombardi
Globally, an estimated 300 million people have asthma, presenting a considerable and increasing burden of disease for healthcare systems, families, and patients themselves. Despite two decades of guidelines, asthma seems to remain not optim...
Robyn T Cohen,Elizabeth S Klings,Robert C Strunk
Robyn T Cohen
Sickle cell disease (SCD) is the most common life-limiting genetic disease among African Americans, affecting more than 100,000 people in the United States. Respiratory disorders in patients with sickle cell disease have been associated wit...
Small airway dysfunction and bronchial asthma control : the state of the art [0.03%]
小气道功能障碍与支气管哮喘控制：现状及展望
Marcello Cottini,Carlo Lombardi,Claudio Micheletto
Marcello Cottini
According to national and international guidelines, achieving and maintaining asthma control is a major goal of disease management. In closely controlled clinical trials, good asthma control can be achieved , with the medical treatments cur...