The problem with relying on profit-driven models to produce pandemic drugs [0.03%]
依赖盈利模式研发大流行病药物的问题
Yaniv Heled,Ana Santos Rutschman,Liza Vertinsky
Yaniv Heled
In this article, we explain why profit-driven models for developing treatments for epidemic pathogens produce sub-optimal and sometimes negative public health outcomes. Using the example of the drug remdesivir, we demonstrate how the diverg...
H D Gunnarsdóttir,M S Sinha,S Gerke et al.
H D Gunnarsdóttir et al.
As the COVID-19 pandemic continues to ravage the globe, many nations have started to relax stringent restrictions in an effort to restart the economy. While Member States of the European Union have approached reopening without the use of an...
Holly Fernandez Lynch,Neal W Dickert,Patricia J Zettler et al.
Holly Fernandez Lynch et al.
Clinical research is critical to combatting COVID-19, but regulatory requirements for human subjects protection may sometimes pose a challenge in pandemic circumstances. Although regulators have offered some helpful guidance for research du...
Francesca Bellazzi,Konrad V Boyneburgk
Francesca Bellazzi
The global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or coronavirus disease 19 (COVID-19) has led to the imposition of severely restrictive measures by governments in the Western hemisphere. We feel a contrast b...
Chaarushena Deb,Osman Moneer,W Nicholson Price nd
Chaarushena Deb
Ciara Staunton,Carmen Swanepoel,Melodie Labuschaigne
Ciara Staunton
Setting priorities fairly in response to Covid-19: identifying overlapping consensus and reasonable disagreement [0.03%]
应对新冠疫情的公平优先排序：识别共识和合理分歧
David Wasserman,Govind Persad,Joseph Millum
David Wasserman
Proposals for allocating scarce lifesaving resources in the face of the Covid-19 pandemic have aligned in some ways and conflicted in others. This paper attempts a kind of priority setting in addressing these conflicts. In the first part, w...
Ruqaiijah Yearby,Seema Mohapatra
Ruqaiijah Yearby
The enhanced danger of physicians' off-label prescribing during a public health emergency [0.03%]
公共卫生紧急状态下医生超适应症用药的潜在危害加剧
Doriane Lambelet Coleman,Philip M Rosoff
Doriane Lambelet Coleman
Treatment of the novel COVID-19: why Costa Rica's proposal for the creation of a global pooling mechanism deserves serious consideration? [0.03%]
治疗新冠的新思路：为何哥斯达黎加提议建立全球共享机制值得认真考虑？
Muhammad Zaheer Abbas
Muhammad Zaheer Abbas
The COVID-19 is causing not only deaths and fear but also economic and social harm across the globe. Lockdowns, travel restrictions, quarantines, social distancing, and other strict public health measures are playing their part in delaying ...