Cerebellar transcranial direct current stimulation reconfigurates static and dynamic functional connectivity of the resting-state networks [0.03%]
经颅直流电刺激小脑可以重塑静息态网络的功能连接模式
F Grami,G de Marco,F Bodranghien et al.
F Grami et al.
Background: Transcranial direct current stimulation (tDCS) of the cerebellum dynamically modulates cerebello-thalamo-cortical excitability in a polarity-specific manner during motor, visuo- motor and cognitive tasks. It r...
Indirect immunofluorescent assay as an aid in the diagnosis of suspected immune mediated ataxias [0.03%]
间接免疫荧光法作为疑似自身免疫性共济失调诊断的辅助手段
Marios Hadjivassiliou,Graeme Wild,Priya Shanmugarajah et al.
Marios Hadjivassiliou et al.
Background and purpose: Immune mediated cerebellar ataxias account for a substantial proportion of all progressive ataxias. A diagnostic serological test is not always available. This is particularly problematic in Primar...
Cerebrotendinous Xanthomatosis: diversity of presentation and refining treatment with chenodeoxycholic acid [0.03%]
脑腱黄瘤病的多样化表现及用鹅去氧胆酸治疗该病的疗效观察
Mahjabin Islam,Nigel Hoggard,Marios Hadjivassiliou
Mahjabin Islam
Background: Cerebrotendinous xanthomatosis (CTX) is a rare but treatable neurometabolic disorder of lipid storage and bile acid synthesis. Whilst CTX is said to present with the classic triad of juvenile onset cataracts, ...
Cerebellar ataxia and exercise intolerance in Erdheim-Chester disease [0.03%]
Erdheim-Chester 病的小脑共济失调和运动不耐受
Eleonora Lauricella,Antonio d&#x;Amati,Giuseppe Ingravallo et al.
Eleonora Lauricella et al.
Background: Erdheim-Chester disease (ECD), a rare disorder of monocyte/macrophage lineage, has been related to cerebellar dysfunction. To increase the awareness of this rare, protean disease, an unusual, myasthenia-like o...
Friedreich ataxia in COVID-19 time: current impact and future possibilities [0.03%]
COVID-19时期的弗里德赖希共济失调：当前影响及未来展望
Tommaso Schirinzi,Andrea Sancesario,Enrico Castelli et al.
Tommaso Schirinzi et al.
COVID-19 outbreak profoundly impacted on daily-life of patients with neurodegenerative diseases, including those with ataxia. Effects on interventional trials have been recently described. Conversely, changes in physical activity programs, ...
Investigating the effects of cerebellar transcranial direct current stimulation on saccadic adaptation and cortisol response [0.03%]
探究针对小脑的经颅直流电刺激对动眼适应及皮质醇反应的影响
Delia A Gheorghe,Muriel T N Panouillères,Nicholas D Walsh
Delia A Gheorghe
Background: Transcranial Direct Current Stimulation (tDCS) over the prefrontal cortex has been shown to modulate subjective, neuronal and neuroendocrine responses, particularly in the context of stress processing. However...
The critical need to develop tools assessing cerebellar reserve for the delivery and assessment of non-invasive cerebellar stimulation [0.03%]
评估小脑储备以输送和评估非侵入性小脑刺激的工具开发的迫切需要
Mario Manto,Shinji Kakei,Hiroshi Mitoma
Mario Manto
Non-invasive cerebellar stimulation (NICS) aims to modulate cerebello-cerebral loops and cerebro-spinal loops, both for research and clinical applications. It is of paramount importance to establish and validate morphological and functional...
The complexity of eye-hand coordination: a perspective on cortico-cerebellar cooperation [0.03%]
眼手协调的复杂性：关于皮层小脑合作的视角
John-Ross Rizzo,Mahya Beheshti,Tahereh Naeimi et al.
John-Ross Rizzo et al.
Background: Eye-hand coordination (EHC) is a sophisticated act that requires interconnected processes governing synchronization of ocular and manual motor systems. Precise, timely and skillful movements such as reaching f...
Should we investigate mitochondrial disorders in progressive adult-onset undetermined ataxias? [0.03%]
我们应该对进行性成人起病的病因未明的共济失调患者进行线粒体疾病的相关检查吗？
José Luiz Pedroso,Wladimir Bocca Vieira de Rezende Pinto,Orlando Graziani Povoas Barsottini et al.
José Luiz Pedroso et al.
Background: Despite the broad development of next-generation sequencing approaches recently, such as whole-exome sequencing, diagnostic workup of adult-onset progressive cerebellar ataxias without remarkable family histor...
Case Reports
Cerebellum & ataxias. 2020 Aug 24:7:13. DOI:10.1186/s40673-020-00122-0 2020
Elan D Louis,Phyllis L Faust
Elan D Louis
Background: The degenerative cerebellar ataxias comprise a large and heterogeneous group of neurological diseases whose hallmark clinical feature is ataxia, and which are accompanied, to variable degrees, by other feature...