Sarcomatoid cutaneous squamous cell carcinoma of the heel: a rare localization of an aggressive variant of cutaneous squamous cell carcinoma [0.03%]
Line Farhat,Ouiame Eljouari,Salma Fahmi et al.
Line Farhat et al.
Sarcomatoid cutaneous squamous cell carcinoma (SCSCC) is a rare and aggressive variant of squamous cell carcinoma characterized by spindle-cell morphology resulting from epithelial-mesenchymal transition rather than true biphasic differenti...
Hemispheric H3K27M-mutant diffuse glioma in an adult: a rare entity with ATRX loss and Oligodendroglioma-like features [0.03%]
Ghaida S AlSugair,Mohammad Anas Dababo
Ghaida S AlSugair
The H3K27M genetic alteration is frequent in diffuse midline gliomas but rare in hemispheric diffuse gliomas. We report a rare case of a hemispheric H3K27M-mutant high-grade glioma in a 21-year-old female who presented with a seizure. Brain...
From sinusitis to blindness: an unusual case of Pott's puffy tumor with bilateral optic atrophy [0.03%]
Marouane Jidal,Soufiane Ibat,Youssra Kramchi et al.
Marouane Jidal et al.
Introduction: Pott's puffy tumor (PPT) is a rare complication of sinusitis and is defined as a subperiosteal abscess with frontal bone osteomyelitis. Intracranial and orbital complications occur frequently. ...
Isolated post-traumatic Intracholecystic Hemorrhage without Gallbladder Wall rupture: a rare diagnostic challenge [0.03%]
Steffani Simone,Laudazi Mario,Chiocchi Marcello et al.
Steffani Simone et al.
Blunt abdominal trauma rarely results in isolated gallbladder injury. Intracholecystic hemorrhage without concomitant liver injury or gallbladder wall rupture is an uncommon presentation. We report the case of a 55-year-old male presenting ...
Thomas J Sorenson,Nihkil Agrawal
Thomas J Sorenson
First culture-confirmed melioidosis case in Mozambique: a wakeup call for better diagnostics and clinical awareness [0.03%]
Shehezady Charfudine Cruz,Cedalia Raimundo,Leonel Andela et al.
Shehezady Charfudine Cruz et al.
Melioidosis is a disease caused by Burkholderia pseudomallei and is an underrecognised cause of severe infection in sub-Saharan Africa. In Mozambique, where infectious diseases are prevalent, and laboratory capacity remains limited, it has ...
A diagnostic pitfall in cold agglutinin disease: KMT2D-mutated CAD-associated lymphoproliferative disorder with a CLL-like immunophenotype [0.03%]
Yusuke Okamoto,Hiroshi Arima,Kenichi Ishiyama et al.
Yusuke Okamoto et al.
Cold agglutinin disease (CAD) is an uncommon hemolytic anemia by complement-fixing IgM autoantibodies and is frequently associated with a distinct clonal B-cell lymphoproliferative disorder (CAD-LPD). We report a woman in her 50's with prog...
Nivolumab-associated hypopituitarism in a 61-year-old woman with metastatic triple-negative breast [0.03%]
Ketevan Lomidze,Marine Gordeladze,Nino Kikodze et al.
Ketevan Lomidze et al.
Immune checkpoint inhibitors (ICIs) have transformed the treatment landscape of cancer, enhancing response rates and survival outcomes. However, immune-related adverse events (irAEs), which can affect any organ or system, can limit their us...
Treponemal Endovasculitis leading to branch artery occlusion: a rare manifestation of ocular syphilis [0.03%]
Kakarla V Chalam,Lourdes Ceja,Anny M S Cheng
Kakarla V Chalam
Ocular syphilis, a re-emerging cause of uveitis, commonly features retinal vasculitis, but branch retinal artery occlusion (BRAO) is a rare, irreversible damaging complication. We present a 47-year-old woman with bilateral syphilitic panuve...
Severe Euglycemic diabetic ketoacidosis with mixed Acid-Base disorder following acetazolamide initiation in type 2 diabetes: a case report and review of literature [0.03%]
Saif Khaled Abdalhadi Azzam,Lina Barhoum Barhoum,Salih AbuRajab et al.
Saif Khaled Abdalhadi Azzam et al.
Euglycemic diabetic ketoacidosis (euDKA) is an increasingly recognized complication of sodium-glucose cotransporter-2 (SGLT2) inhibitor therapy, characterized by severe metabolic acidosis with near-normal blood glucose levels. We report a r...