Superparamagnetic iron oxide nanoparticle restores gut microbiota homeostasis to enhance lung cancer immunotherapy [0.03%]
超参数铁氧化纳米颗粒恢复肠道微生物群稳态以增强肺癌免疫治疗
Yayi He,Wengang Zhang,Zhanhang Guo et al.
Yayi He et al.
Emerging evidence indicates that gut microbiota dysbiosis markedly compromises the efficacy of lung cancer immunotherapy. In our study, superparamagnetic iron oxide nanoparticle assemblies (SPIOCAs) were developed and shown to effectively i...
Hepeng Jia
Hepeng Jia
Heavy investments, novel institutions and intra-regional ties are fueling the scientific rise of the Guangdong-Hong Kong-Macao Greater Bay Area. © The A...
Achieving over 200 Wh kg-1 sodium-ion pouch cell by quantitative engineering of hard carbon pores [0.03%]
通过量化工程实现硬碳孔的200Wh/kg钠离子软包电池
Zhihao Chen,Jialong Shen,Wenjie Deng et al.
Zhihao Chen et al.
Energy-dense sodium-ion batteries (SIBs) offer lithium-free, cost-effective solutions for grid-scale energy storage. However, the structural complexity of hard carbon (HC) anodes hinders the establishment of a clear structure-performance re...
MINFLUX dissects nucleosome and compacting chromatin structures in living cells [0.03%]
MINFLUX解剖活细胞中的核小体和致密染色质结构
Hong Xie,Yi Hu,Ruixi Cheng et al.
Hong Xie et al.
The chromatin structure is fundamental for genome compaction and gene transcriptional regulation in the nucleus. Although in vitro studies suggest a classical model that 11-nm nucleosome polymers fold into 30 nm fibers, such structures have...
Pan-membrane pyroptosis of liver induced by gasdermin-encoding mRNAs [0.03%]
Gasdermin编码的mRNA诱导的肝跨膜焦亡
Yi-Jiao Huang,Lin Li,Guan Yang et al.
Yi-Jiao Huang et al.
Gasdermin (GSDM)-mediated pyroptosis has been extensively visualized in vitro and linked to multiple physiological and pathological processes. However, the in vivo phenotype and clinical outcome of pyroptosis remain undetermined. Here, we s...
Critical transition of urban ozone formation regime in the North China Plain [0.03%]
中国华北平原城市臭氧生成模式的关键转换点
Likun Xue,Yujiao Zhu,Jian Gao et al.
Likun Xue et al.
Over the past decade, China has achieved remarkable progress in mitigating aerosol pollution. However, ozone (O3) pollution still shows a worsening trend, implying that China's control measures may have been less effective in tackling O3 po...
Mengqi Li,Honglong Hu,Zhi-Gang Zheng et al.
Mengqi Li et al.
Helical organization in soft materials is omnipresent in systems ranging from DNA and peptides to liquid crystal displays. Dynamic transformation and reconfiguration of helicity triggered non-invasively by light are highly desirable, yet ch...
Singlet and triplet harvesting enable efficient NIR-II quantum-dot electroluminescence [0.03%]
单重态和三重态收获使有效的近红外II量子点电致发光成为可能
Wan-Shan Shen,Sam Teale,Yang Liu et al.
Wan-Shan Shen et al.
Colloidal quantum dots (CQDs) are promising materials for constructing 'second-window' near-infrared (1000-1700 nm) light-emitting diodes (NIR-II LEDs), but their practical application has been hampered by low film external quantum efficien...
The funding effectiveness in chemistry at the National Natural Science Foundation of China: research progress on the fundamentals and applications of zeolite materials [0.03%]
中国国家自然科学基金化学学科的资助效果——沸石材料基础与应用研究进展
Wei-Li Dai,Li-Hua Chen,Chang Yao et al.
Wei-Li Dai et al.
Zeolites have undergone a significant development, leading to their widespread application in catalytic processes. China plays a pivotal role in the rapid growth of pioneering zeolite research. The National Natural Science Foundation of Chi...
Bienzyme-powered nanorobots with ultrasensitive chemotaxis for precision cancer therapy [0.03%]
用于精准癌症治疗的超灵敏化学趋向型双酶纳米机器人
Zili Yang,Ziye Pei,Zhixue Gao et al.
Zili Yang et al.
Low tumor-targeting delivery efficiency (Ɛ) and poor tumor penetration remain critical issues in the clinical translation of nanoparticle-based drug delivery systems. Here we report that bienzyme-powered Janus nanorobots with catalase and ...