Women's IschemiA TRial to Reduce Events In Non-ObstRuctive CAD (WARRIOR): a randomised controlled trial [0.03%]
女性缺血事件减少非梗阻性冠心病随机对照试验(WARRIOR)
Carl J Pepine,Eileen Handberg,Rhonda Cooper-DeHoff et al.
Carl J Pepine et al.
Importance: Women with angina due to suspected ischaemia referred for coronary angiography often have no obstructive coronary artery disease (ANOCA/INOCA). ...
Randomized Controlled Trial
Open heart. 2026 Apr 3;13(1):e004115. DOI:10.1136/openhrt-2026-004115 2026
Periprocedural evaluation of patients with BAV stenosis undergoing TAVR: a machine learning-based study [0.03%]
基于机器学习的生物主动脉瓣狭窄经导管主动脉瓣置换术患者术前评估研究
Yu Mao,Yu Chen,Mengen Zhai et al.
Yu Mao et al.
Background: Transcatheter aortic valve replacement (TAVR) has increasingly emerged as one of the primary treatments for patients with severe bicuspid aortic valve (BAV) stenosis. Nevertheless, these patients encounter mul...
Multicenter Study
Open heart. 2026 Apr 3;13(1):e003749. DOI:10.1136/openhrt-2025-003749 2026
Increase in cardiovascular deaths during the COVID-19 pandemic in Peru: a 5-year analysis of the national death system [0.03%]
新冠肺炎疫情期间秘鲁心血管死亡率上升：全国死亡系统5年分析结果
Jeel Moya-Salazar,Jhonny Rivera,Eileen A Marín et al.
Jeel Moya-Salazar et al.
Introduction: Cardiovascular diseases (CVDs) are the leading cause of death globally, with increasing prevalence and mortality rates. The COVID-19 pandemic has exacerbated CVD-related morbidity and mortality, particularly...
Observational Study
Open heart. 2026 Apr 2;13(1):e003729. DOI:10.1136/openhrt-2025-003729 2026
Andrea Csillik,Rita Gagyi,Gergő József Szőllősi et al.
Andrea Csillik et al.
Background and aims: Over the past decades, high-volume lead extraction centres gained broad experience in advanced transvenous lead extractions (TLE). However, access to advanced TLE techniques is limited, thus it would ...
Specialised heart valve clinics result in greater adherence to guideline-directed care: a comparative study [0.03%]
专科心脏瓣膜门诊可提高循证治疗的遵从性：一项对比研究
Natalie Montarello,Curtis Page,Sophie Bennett et al.
Natalie Montarello et al.
Introduction: International guidelines emphasise the role of heart valve centres (HVC) and specialist heart valve clinics (SHVC) to deliver optimal care to patients with heart valve disease (HVD). We sought to determine w...
Comparative Study
Open heart. 2026 Mar 31;13(1):e003608. DOI:10.1136/openhrt-2025-003608 2026
Mortality in patients with ventricular septal defect in Sweden: a national register study [0.03%]
瑞典室间隔缺损患者的死亡率：一项全国登记处研究
Per Lundberg,Maria Fedchenko,Kok Wai Giang et al.
Per Lundberg et al.
Objectives: Ventricular septal defect (VSD) is the most common congenital heart defect. Much remains unclear about the long-term prognosis for VSD patients. This study aimed to investigate the all-cause and cardiovascular...
Multicenter Study
Open heart. 2026 Mar 31;13(1):e004098. DOI:10.1136/openhrt-2026-004098 2026
Tofacitinib in the treatment of cardiac sarcoidosis: towards steroid-sparing disease management [0.03%]
托法替尼在心脏结节病治疗中的应用：朝向减少使用皮质类固醇的疾病管理方向
Lukas Frischknecht,Melina Stüssi-Helbling,Yuan Tian et al.
Lukas Frischknecht et al.
Background: Cardiac sarcoidosis (CS) creates complex treatment challenges, especially for patients who fail to respond to immunosuppressive drugs, including second-line tumour necrosis factor inhibitors. These refractory ...
Outcomes according to timely or delayed primary percutaneous coronary intervention or fibrinolysis in a national registry of patients with ST-segment elevation myocardial infarction [0.03%]
斯蒂尔曼抬高性心肌梗死登记患者的直接PCI或溶栓治疗的及时性和延迟性的结果分析
Jack Laffan,Huixuan Gao,Andrew Street et al.
Jack Laffan et al.
Background: Time to reperfusion is a predictor of long-term outcomes in ST-segment elevation myocardial infarction (STEMI). Timely primary percutaneous coronary intervention (PCI) is the preferred strategy recommended by ...
Observational Study
Open heart. 2026 Mar 31;13(1):e003886. DOI:10.1136/openhrt-2025-003886 2026
Genotype-phenotype correlations in patients with pathogenic/likely pathogenic titin variants from the Swiss Arrhythmogenic Cardiomyopathy Registry [0.03%]
瑞士心律失常性心肌病注册表中致病型/可能致病型TTN变异患者的基因型表型相关性
Nina Alissa Schätti,Siv Fokstuen,Argelia Medeiros-Domingo et al.
Nina Alissa Schätti et al.
Background: Truncating variants in the titin gene (TTNtv) are associated with cardiomyopathy, mainly dilated cardiomyopathy (DCM). The clinical presentation and outcomes of arrhythmogenic phenotypes in these patients are ...
Multicenter Study
Open heart. 2026 Mar 31;13(1):e003750. DOI:10.1136/openhrt-2025-003750 2026
Effects of ACE inhibitor and afterload reduction in single ventricles following bidirectional Glenn [0.03%]
双向葛lenn术后单心室血管紧张素转换酶抑制剂和后负荷降低的效果
David M Biko,Cassie Giner,Andrea L Jones et al.
David M Biko et al.
Background: Patients with single ventricles after bidirectional Glenn (BDG) are placed on ACE inhibitors (ACEIs) to reduce afterload and to decrease systemic to pulmonary collateral flow (SPC). The objective is to determi...