Epidemiology, economic burden and mortality of atrial fibrillation in a region with very high life expectancy: a contemporary, population-based analysis in Catalonia [0.03%]
高寿命地区房颤的流行病学、经济负担和死亡率：来自 Catalonia 的当代人群队列分析研究
Benjamin Casteigt,Emili Vela,Ermengol Valles et al.
Benjamin Casteigt et al.
Background: The high prevalence of atrial fibrillation (AF) and its association with cardiovascular (CV) outcomes represent a challenge for public health systems, particularly in ageing societies. ...
Multicenter Study
Open heart. 2026 Apr 17;13(1):e004007. DOI:10.1136/openhrt-2026-004007 2026
Non-invasive endotyping improves treatment satisfaction and prescribing appropriateness in patients with angina and no obstructive coronary artery disease [0.03%]
无创表型分型可改善冠状动脉正常的心绞痛患者的治疗满意度及用药合理性
Conor P Bradley,Gemma McKinley,Vanessa Orchard et al.
Conor P Bradley et al.
Background: Patients with angina and no obstructive coronary artery disease (ANOCA) frequently receive empirical antianginal therapy that fails to target underlying pathophysiological mechanisms. Whether stress perfusion ...
Randomized Controlled Trial
Open heart. 2026 Apr 17;13(1):e004135. DOI:10.1136/openhrt-2026-004135 2026
Long-term outcomes of mitral valve surgery in infective endocarditis: a single-centre UK experience [0.03%]
感染性心内膜炎二尖瓣手术的长期效果：英国单中心经验
Aziz Momin,Redoy Ranjan,William Sowden et al.
Aziz Momin et al.
Background: The optimal surgical strategy for mitral valve (MV) infective endocarditis (IE) remains uncertain. Although valve repair is increasingly advocated, MV replacement is frequently performed, and robust data compa...
Combined effect of educational attainment and diabetes on 1-year all-cause mortality in heart failure patients: findings from the National Heart Failure Registry, India [0.03%]
教育背景和糖尿病对印度心力衰竭患者1年全因死亡率联合影响的前瞻性研究：来自印度国家心力衰竭登记处的数据
Panniyammakal Jeemon,Sunu C Thomas,Ajay Bahl et al.
Panniyammakal Jeemon et al.
Background: Patients with coexisting heart failure (HF) and diabetes mellitus are often prescribed complex treatment regimens, which can contribute to adverse clinical outcomes. However, the impact of such therapeutic com...
Multicenter Study
Open heart. 2026 Apr 15;13(1):e003833. DOI:10.1136/openhrt-2025-003833 2026
Chronotype-aligned exercise timing in middle-aged adults at cardiometabolic risk: a randomised controlled trial [0.03%]
中年心血管代谢风险成年人生物钟同步运动时间的随机对照试验
Arsalan Tariq,Mohammed Harris Khalid,Muhammad Ammar
Arsalan Tariq
Objective: To investigate whether aligning exercise timing with chronotype enhances cardiometabolic and sleep-related benefits in sedentary adults with cardiovascular risk factors. ...
Randomized Controlled Trial
Open heart. 2026 Apr 14;13(1):e003573. DOI:10.1136/openhrt-2025-003573 2026
Sex differences in risk factor control and medication adherence post-ACS: insights from the TEXTMEDS randomised clinical trial [0.03%]
急性冠脉综合征后危险因素控制及服药依从性的性别差异：TEXTMEDS随机临床试验的新启示
Shiva Raj Mishra,Simone Marschner,Haeri Min et al.
Shiva Raj Mishra et al.
Introduction: Poor adherence to risk factor control and life-saving medications is a key factor affecting long-term patient prognosis. Evidence indicates that sex plays a significant role in the uptake of both pharmacolog...
Randomized Controlled Trial
Open heart. 2026 Apr 9;13(1):e003856. DOI:10.1136/openhrt-2025-003856 2026
Mortality reduction and survival extension in cardiovascular trials: why language matters [0.03%]
心血管试验中的降低死亡率和延长生存期：为何措辞很重要
Francesco Tona
Francesco Tona
In cardiovascular medicine, claims of 'mortality reduction' are widely used to summarise the benefits of contemporary therapies. The phrase carries a powerful and intuitive meaning, suggesting that deaths have been prevented and lives have ...
Effect of a mobile health intervention optimised with artificial intelligence on blood pressure and other cardiovascular risk factors in adults with high blood pressure: rationale and design of My Intelligent Cardiac Assistant (MICArdiac) randomised controlled trial [0.03%]
基于人工智能优化的移动健康干预对高血压成人血压和其他心血管风险因素的影响：My Intelligent Cardiac Assistant（MICArdiac）随机对照试验的方案和设计
Liliana Laranjo,Edel T O&#x;Hagan,Harry Klimis et al.
Liliana Laranjo et al.
Introduction: Control of blood pressure (BP) continues to be a challenge globally. Clinical trials have shown home BP monitoring and text-message interventions to lower BP. Integrating these to personalise supportive mess...
Prognostic value of cardiac fibroblast activation heterogeneity assessed by FAPI PET radiomics in hypertrophic cardiomyopathy: a proof-of-concept study [0.03%]
FAPI-PET影像组学评估心脏成纤维细胞活化异质性对肥厚型心肌病预后价值的概念验证研究
Haoyu Song,Jie Ding,Jun Zhao et al.
Haoyu Song et al.
Background: Hypertrophic cardiomyopathy (HCM) is associated with an increased risk of sudden cardiac death (SCD), and myocardial fibrosis plays a central role in the pathophysiology process. Radiolabelled fibroblast activ...
Multicenter Study
Open heart. 2026 Apr 6;13(1):e003537. DOI:10.1136/openhrt-2025-003537 2026