Development and validation of a 10-year predictive model for cardiovascular and metabolic disease risk: insights from a large-scale health examination cohort [0.03%]
心血管代谢疾病风险的10年预测模型的开发与验证：来自大规模健康体检队列的新视角
Dejie Wang,Jiang-Shan Tan,Ruihan Liu et al.
Dejie Wang et al.
Objective: To develop and validate a 10-year predictive model for cardiovascular and metabolic disease (CVMD) risk using comprehensive health examination data from nearly 37 701 individuals. ...
Feasibility of screening for heart failure in Africa: barriers and facilitators in a low-resourced setting [0.03%]
非洲心力衰竭筛查的可行性：低资源条件下存在的障碍和促进因素
Neusa Jessen,Albertino Damasceno,Pardeep Jhund
Neusa Jessen
Heart failure (HF) is of worldwide public health concern, yet with higher morbidity and mortality in low- and middle-income countries compared with high-income nations, posing a significant burden to the already overstrained and unprepared ...
Prognostic impact of mitral regurgitation in elderly patients with atrial fibrillation: results from the CABANA trial [0.03%]
二尖瓣反流对房颤患者预后的影响:CABANA试验的结果
Qinchao Wu,Lili Wang,Yanguang Li et al.
Qinchao Wu et al.
Background: Mitral regurgitation (MR) is the most common valvular heart disease and the most common comorbidities of atrial fibrillation (AF), which is prevalent with age. Nonetheless, the prognosis of MR in elderly patie...
Randomized Controlled Trial
Open heart. 2025 Nov 27;12(2):e003478. DOI:10.1136/openhrt-2025-003478 2025
Adherence to the European Society of Cardiology hypertension guidelines over 12 years of follow-up in the Irish population [0.03%]
爱尔兰人群12年随访中欧洲心脏病学会高血压指南的遵循情况
Caoimhe McGarvey,Siobhan Scarlett,Robert Briggs et al.
Caoimhe McGarvey et al.
Background: Hypertension is a significant risk factor for cardiovascular disease, dementia and chronic kidney disease (CKD). Older adults bear the brunt of these conditions, and managing hypertension can be especially cha...
Multicenter Study
Open heart. 2025 Nov 28;12(2):e003744. DOI:10.1136/openhrt-2025-003744 2025
Analysis of left ventricular mass for African American individuals using multi-ancestry polygenic risk scores: the Jackson Heart Study [0.03%]
利用多族系基因风险评分分析非洲裔美国人左心室质量——来自杰克逊心脏研究的证据
Douglas McLaurin,Philip Turk,Olivia Affuso et al.
Douglas McLaurin et al.
Background: Left ventricular mass (LVM) is suggested to be a sensitive predictor of adverse cardiovascular outcomes, such as heart failure. In recent years, genome-wide association studies have discovered loci that associ...
Multicenter Study
Open heart. 2025 Nov 27;12(2):e003501. DOI:10.1136/openhrt-2025-003501 2025
Comparative analysis of clinical scores in predicting ICU and hospital mortality in nonagenarians and centenarians after in-hospital cardiac arrest: a retrospective observational study using the Australian and New Zealand Intensive Care Society (ANZICS) Adult Patient Database (2010-2024) [0.03%]
基于澳大利亚和新西兰重症监护学会成人患者数据库（2010-2024）的回顾性观察研究：比较临床评分在院内心脏骤停后90岁及以上老年人ICU和医院病死率预测中的作用分析
Je Min Suh,Laurence Weinberg,Jiaying Ye et al.
Je Min Suh et al.
Background: Nonagenarians and centenarians admitted to intensive care units (ICUs) following in-hospital cardiac arrest (IHCA) represent a growing yet understudied population. Clinicians require accurate prognostic tools ...
Observational Study
Open heart. 2025 Nov 19;12(2):e003524. DOI:10.1136/openhrt-2025-003524 2025
Efficacy and safety of direct oral anticoagulants versus warfarin in patients with a left ventricular thrombus: an updated systematic review and meta-analysis of randomised controlled trials [0.03%]
直接口服抗凝药与华法林在左心室血栓患者中的疗效和安全性：随机对照试验的更新系统评价和meta分析
Thomaz Alexandre Costa,Gabriel Cavalcante Lima Chagas,Luma Maria Tavares de Sousa et al.
Thomaz Alexandre Costa et al.
Background: Left ventricular (LV) thrombus is a complication of myocardial infarction and dilated cardiomyopathy and is associated with a high thromboembolic risk. Although warfarin has traditionally been used, direct ora...
Meta-Analysis
Open heart. 2025 Nov 19;12(2):e003542. DOI:10.1136/openhrt-2025-003542 2025
Long-term outcome of patients with Eisenmenger syndrome receiving pulmonary arterial hypertension-targeted therapy [0.03%]
接受肺动脉高压靶向治疗的艾森曼格综合征患者的长期预后
Hideo Matama,Ryotaro Asano,Hiroyuki Endo et al.
Hideo Matama et al.
Background: Eisenmenger syndrome (ES) is a severe and fatal complication of uncorrected congenital heart disease characterised by the development of pulmonary arterial hypertension (PAH) due to chronic left-to-right shunt...
Comparing access to, and outcomes following, TAVI by biological sex [0.03%]
基于生物学性别的经导管主动脉瓣植入术的可及性和预后比较
James Dargan,Oliver Rees,Laura Bijman et al.
James Dargan et al.
Introduction: European valvular heart disease guidelines define women as a 'special group'. To explore what factors have led us to consider more than 50% of the global population special, we assessed access to transcathet...
Comparative Study
Open heart. 2025 Nov 13;12(2):e003599. DOI:10.1136/openhrt-2025-003599 2025
Zaidon AlFalahi,Dylan Rajaratnam,Srisa Boddupalli et al.
Zaidon AlFalahi et al.
Background: Heart failure (HF) is a major cause of morbidity and mortality worldwide. Despite significant improvements in the management of HF, the overall outcome remains poor. In addition to pharmacotherapy and device t...
Observational Study
Open heart. 2025 Nov 13;12(2):e003575. DOI:10.1136/openhrt-2025-003575 2025