Renal function trajectories in 'De Novo' heart failure with reduced ejection fraction: impact on outcomes [0.03%]
射血分数降低的新发心力衰竭患者的肾功能变化轨迹及其对预后的影响
Oscar Otero Garcia,Víctor Donoso Trenado,Pablo de la Fuente-López et al.
Oscar Otero Garcia et al.
Aims: Heart failure (HF) often coexists with chronic kidney disease (CKD), impacting prognosis. This study aims to evaluate renal function trajectories and their impact on major clinical outcomes in a cohort of patients h...
Multicenter Study
Open heart. 2026 Feb 6;13(1):e003193. DOI:10.1136/openhrt-2025-003193 2026
200 J-first, fixed-escalation biphasic electrical cardioversion for atrial fibrillation >48 hours in the emergency department: a single-centre retrospective observational study [0.03%]
急诊科应用200J首次放电和固定升级第二放电双向电复律治疗持续超过48小时房颤的单中心回顾性观察研究
Jakub Nozewski,Zbigniew Siudak,Barbra E Backus et al.
Jakub Nozewski et al.
Background: Guidelines permit up to 360 J for synchronised biphasic electrical cardioversion (ECV) in atrial fibrillation (AF) lasting >48 hours. The CHESS randomised trial reported higher first-shock success with fixed 3...
Observational Study
Open heart. 2026 Feb 4;13(1):e003875. DOI:10.1136/openhrt-2025-003875 2026
Clinical outcomes of pulsed field versus radiofrequency ablation, incorporating posterior wall isolation, in persistent atrial fibrillation [0.03%]
分步消融与环肺静脉后壁隔离治疗持续性房颤的临床疗效分析
Omar Ahmed,Anthony Li,Ibrahim Zazai et al.
Omar Ahmed et al.
Background: Persistent atrial fibrillation (AF) remains challenging to treat with catheter ablation. The left atrial posterior wall (PW) may represent an important non-pulmonary vein (PV) substrate; however, randomised tr...
Comparative Study
Open heart. 2026 Feb 4;13(1):e003798. DOI:10.1136/openhrt-2025-003798 2026
Modelling the coverage gap in percutaneous coronary intervention in LMIC: a geospatial analysis of cath lab coverage in Indonesia [0.03%]
低收入和中等收入国家经皮冠状动脉介入治疗覆盖率缺口的建模：印度尼西亚导管实验室覆盖率的地理空间分析
Iwan Dakota,Farizal Rizky Muharram,Chaq El Chaq Zamzam Multazam et al.
Iwan Dakota et al.
Background: International guidelines recommend percutaneous coronary intervention within 120 min for high-risk acute coronary syndrome. In Indonesia, a sprawling archipelago with a rising cardiovascular burden, the minist...
Bridging machine learning and clinical practice: a multicentre nomogram for 90-day graft failure risk stratification in heart transplantation [0.03%]
连接机器学习和临床实践：心脏移植后90天移植物失败风险分层的多中心预测列线图
Wai Yen Yim,Yating Li,Jincheng Hou et al.
Wai Yen Yim et al.
Background: Early graft failure within 90 postoperative days is the leading cause of mortality after heart transplantation. Existing risk scores, based on linear regression, often struggle to capture the complex, multifac...
Multicenter Study
Open heart. 2026 Feb 2;13(1):e003790. DOI:10.1136/openhrt-2025-003790 2026
Association between socioeconomic variables and carotid plaque in middle-aged adults: data from the Akershus Cardiac Examination (ACE) 1950 Study [0.03%]
社会经济因素与中年人颈动脉斑块的关系——来自Akershus心脏检查1950研究的数据分析
Åsmund Olaf Bratholm,Håkon Ihle-Hansen,Thea Vigen et al.
Åsmund Olaf Bratholm et al.
Background: Low socioeconomic status (SES) is linked to increased cardiovascular risk, but its association with carotid atherosclerosis in the general population is less well studied. We examined associations between indi...
Efficacy and safety of off-label low-dose compared with standard-dose antiplatelet agents in patients with coronary heart disease: a meta-analysis [0.03%]
冠心病患者小剂量与常规剂量非说明书适应症抗血小板药物疗效和安全性的系统评价和meta分析研究
Zhao Ren,Yichao Shi,Jingwei Zou et al.
Zhao Ren et al.
Background: To compare the efficacy and safety of off-label low-dose versus standard-dose antiplatelet agents in coronary heart disease (CHD) patients, focusing on the evidence gap in comparisons of low-dose versus standa...
Meta-Analysis
Open heart. 2026 Jan 30;13(1):e003839. DOI:10.1136/openhrt-2025-003839 2026
Economic evaluation of a novel dual-energy, large focal lattice-tip catheter versus conventional contact-force sensing radiofrequency catheter, for persistent atrial fibrillation ablation, from the English National Health Service perspective [0.03%]
从英国国民保健制度的角度评估一种新颖的双能量、大焦点晶格消融导管与常规接触力感应射频导管治疗持续性房颤的经济效益研究
Greg Mellor,Vivek Reddy,Prapa Kanagaratnam et al.
Greg Mellor et al.
Introduction: Persistent atrial fibrillation (PersAF) presents a significant clinical and economic burden and is associated with poorer outcomes after catheter ablation compared with paroxysmal atrial fibrillation (AF). P...
Randomized Controlled Trial
Open heart. 2026 Jan 30;13(1):e003770. DOI:10.1136/openhrt-2025-003770 2026
Multidisciplinary team-guided management of severe aortic stenosis: 5-year outcomes following TAVI versus conservative treatment [0.03%]
多学科团队指导的严重主动脉瓣狭窄综合管理：经导管主动脉瓣植入术与保守治疗5年预后对比研究
Jane Manning,Louis J Koizia,Melanie Dani et al.
Jane Manning et al.
Objective: Multidisciplinary team (MDT) meetings are central to treatment decisions in aortic stenosis (AS), particularly for borderline or high-risk patients. This study evaluates long-term, real-world outcomes according...
Comparative Study
Open heart. 2026 Jan 29;13(1):e003872. DOI:10.1136/openhrt-2025-003872 2026
Body weight and mortality in Takotsubo syndrome: insights from the International Takotsubo (InterTAK) Registry [0.03%]
体重大体重与 takotsubo 综合征死亡率的关系：来自国际 takotsubo 注册中心的见解
Barbara Stähli,Victor Schweiger,Victoria Lucia Cammann et al.
Barbara Stähli et al.
Aims: The obesity paradox has been described in different cardiovascular conditions. Data on the association between obesity and outcomes in patients with Takotsubo syndrome (TTS) are lacking. The aim of this study was to...
Observational Study
Open heart. 2026 Jan 29;13(1):e003851. DOI:10.1136/openhrt-2025-003851 2026