Trends in genetic diversity for all Kennel Club registered pedigree dog breeds [0.03%]
英国Kennel Club注册的各类犬种基因多样性的变化趋势
T W Lewis,B M Abhayaratne,S C Blott
T W Lewis
Background: Inbreeding is inevitable in closed populations with a finite number of ancestors and where there is selection. Therefore, management of the rate of inbreeding at sustainable levels is required to avoid the ass...
Genetics and epidemiology of hypothyroidism and symmetrical onychomadesis in the Gordon setter and the English setter [0.03%]
高尔登猎狐梗犬和英国猎狐梗犬甲状腺功能减退症和对称性甲生长不良的遗传学和流行病学研究
Martine Lund Ziener,Stina Dahlgren,Stein Istre Thoresen et al.
Martine Lund Ziener et al.
Background: Hypothyroidism is one of the most common endocrine disorders, whereas symmetrical onychomadesis is a rare claw disease in the general dog population. The aims of this study were to estimate the prevalence of h...
Prevalence and heritability of distichiasis in the English Cocker spaniel [0.03%]
英格兰柯基Spaniel犬双列睫的发病率与遗传率
Tanja Petersen,Helle Friis Proschowsky,Tommy Hardon et al.
Tanja Petersen et al.
Background: Canine distichiasis is a well-known cause of ocular irritation and excessive lacrimation (secretion of tears) in the dog. The term distichiasis originates from the Greek words di and stichos meaning two and ro...
Epidemiological associations between brachycephaly and upper respiratory tract disorders in dogs attending veterinary practices in England [0.03%]
英国犬只执业兽医诊所中头部扁平与上呼吸道疾病之间的流行病学关联
Dan G O&#x;Neill,Caitlin Jackson,Jonathan H Guy et al.
Dan G O&#x;Neill et al.
Background: Brachycephalic dog breeds are increasingly common. Canine brachycephaly has been associated with upper respiratory tract (URT) disorders but reliable prevalence data remain lacking. Using primary-care veterina...
A M Oberbauer,J M Belanger,T Bellumori et al.
A M Oberbauer et al.
Background: Analysis of 88,635 dogs seen at the University of California, Davis Veterinary Medical Teaching Hospital from 1995 to 2010 identified ten inherited conditions having greater prevalence within the purebred dog ...
Analysis of DLA-DQB1 and polymorphisms in CTLA4 in Cocker spaniels affected with immune-mediated haemolytic anaemia [0.03%]
免疫介导溶血性贫血柯基犬DLA-DQB1和CTLA4多态性的分析
Anna J Threlfall,Alisdair M Boag,Francesca Soutter et al.
Anna J Threlfall et al.
Background: Cocker spaniels are predisposed to immune-mediated haemolytic anaemia (IMHA), suggesting that genetic factors influence disease susceptibility. Dog leukocyte antigen (DLA) class II genes encode major histocomp...
Identification of a novel frameshift mutation in the DMD gene as the cause of muscular dystrophy in a Norfolk terrier dog [0.03%]
在日本一只Norfolk梗犬中鉴定出DMD基因新的移码突变
Christopher A Jenkins,Oliver P Forman
Christopher A Jenkins
Background: A Norfolk terrier was referred to the Animal Health Trust neurology department with suspected dystrophin-deficient muscular dystrophy (DD-MD), which was confirmed by clinical workup and immunohistochemistry. ...
Strong selection for behavioural resilience in Australian stock working dogs identified by selective sweep analysis [0.03%]
对澳大利亚牧羊犬的行为韧性进行强选择的鉴定：全基因组扫掠分析
Elizabeth R Arnott,Lincoln Peek,Jonathan B Early et al.
Elizabeth R Arnott et al.
Background: Working dog handlers and breeders have strong opinions on characteristics that are desirable in the breeds that they use to handle stock. Most of these characteristics are related to conformation or behaviour....
Homozygosity mapping and sequencing identify two genes that might contribute to pointing behavior in hunting dogs [0.03%]
纯合度定位和测序鉴定出两个与猎犬指路行为有关的基因
Denis A Akkad,Wanda M Gerding,Robin B Gasser et al.
Denis A Akkad et al.
Background: The domestic dog represents an important model for studying the genetics of behavior. In spite of technological advances in genomics and phenomics, the genetic basis of most specific canine behaviors is largel...
Prevalence of disorders recorded in Cavalier King Charles Spaniels attending primary-care veterinary practices in England [0.03%]
英国初级保健兽医诊所就诊的英格兰查尔士王小猎犬患病情况调查
Jennifer F Summers,Dan G O&#x;Neill,David B Church et al.
Jennifer F Summers et al.
Background: Concerns have been raised over breed-related health issues in purebred dogs, but reliable prevalence estimates for disorders within specific breeds are sparse. Electronically stored patient health records from...