Regina Kropatsch,Denis A Akkad,Matthias Frank et al.
Regina Kropatsch et al.
Background: Progressive retinal atrophy (PRA) belongs to a group of inherited retinal disorders associated with gradual vision impairment due to degeneration of retinal photoreceptors in various dog breeds. PRA is highly ...
Demography and health of Pugs under primary veterinary care in England [0.03%]
英国日常兽医护理环境中蠢柴犬的 demographics 和健康状况
Dan G ONeill,Elisabeth C Darwent,David B Church et al.
Dan G ONeill et al.
Background: The Pug is an ancient dog breed and was the fifth most commonly registered UK pedigree breed in 2014. However, the breed has been reported to be predisposed to several disorders including ocular, respiratory a...
The epidemiology of patellar luxation in dogs attending primary-care veterinary practices in England [0.03%]
英国英格兰接受初级保健的犬髌骨脱位流行病学调查
Dan G ONeill,Richard L Meeson,Adam Sheridan et al.
Dan G ONeill et al.
Background: Canine patellar luxation is one of the most common orthopaedic disorders of dogs and is a potential welfare concern because it can lead to lameness, osteoarthritis and pain. However, there are limited epidemio...
Protein expression and genetic variability of canine Can f 1 in golden and Labrador retriever service dogs [0.03%]
金毛寻回猎犬和拉布拉多寻回猎犬Can f 1的基因多态性和蛋白质表达水平
Christina Breitenbuecher,Janelle M Belanger,Kerinne Levy et al.
Christina Breitenbuecher et al.
Background: Valued for trainability in diverse tasks, dogs are the primary service animal used to assist individuals with disabilities. Despite their utility, many people in need of service dogs are sensitive to the prima...
Trends in popularity of some morphological traits of purebred dogs in Australia [0.03%]
澳大利亚纯种犬一些形态特征受欢迎程度的变化趋势
Kendy T Teng,Paul D McGreevy,Jenny-Ann L M L Toribio et al.
Kendy T Teng et al.
Background: The morphology of dogs can provide information about their predisposition to some disorders. For example, larger breeds are predisposed to hip dysplasia and many neoplastic diseases. Therefore, longitudinal tr...
Prevalence of pectinate ligament dysplasia and associations with age, sex and intraocular pressure in the Basset hound, Flatcoated retriever and Dandie Dinmont terrier [0.03%]
贝獚犬、扁毛寻回犬和丹迪丁蒙特梗犬角膜环状韧带异常的患病率及其与年龄、性别和眼压的关系
James A C Oliver,Abel Ekiri,Cathryn S Mellersh
James A C Oliver
Background: The aims of this study were to: determine the prevalence of pectinate ligament dysplasia (PLD) in populations of Basset hounds (BH), Flatcoated retrievers (FCR) and Dandie Dinmont terriers (DDT) resident in th...
A search for genetic diversity among Italian Greyhounds from Continental Europe and the USA and the effect of inbreeding on susceptibility to autoimmune disease [0.03%]
意大利梗基因多样性研究及其近交对自身免疫疾病易感性的影响
Niels C Pedersen,Hongwei Liu,Angela Leonard et al.
Niels C Pedersen et al.
Background: Previous studies documented the problem of inbreeding among Italian Greyhounds (IG) from the USA and its possible role in a multiple autoimmune disease syndrome. The present study is an extension of these earl...
Evaluation of whole-genome sequencing of four Chinese crested dogs for variant detection using the ion proton system [0.03%]
采用ion proton系统对中国 Crested犬全基因组测序评估用于变异检测的效果
Agnese Viluma,Shumaila Sayyab,Sofia Mikko et al.
Agnese Viluma et al.
Background: Next generation sequencing (NGS) has traditionally been performed by large genome centers, but in recent years, the costs for whole-genome sequencing (WGS) have decreased substantially. With the introduction o...
A cultured approach to canine urothelial carcinoma: molecular characterization of five cell lines [0.03%]
犬膀胱移行细胞癌的分子表征:五株癌细胞系的培养建系及特性分析
S G Shapiro,D W Knapp,Matthew Breen
S G Shapiro
Background: Urothelial carcinoma (UC), also known as transitional cell carcinoma (TCC), of the bladder is the most common neoplasm affecting the canine urogenital system. To facilitate study of the disease in vitro, cell ...
The effect of genetic bottlenecks and inbreeding on the incidence of two major autoimmune diseases in standard poodles, sebaceous adenitis and Addison's disease [0.03%]
遗传瓶颈和近交增加标准贵宾犬两种主要自体免疫疾病发生率的影响研究
Niels C Pedersen,Lynn Brucker,Natalie Green Tessier et al.
Niels C Pedersen et al.
Background: Sebaceous adenitis (SA) and Addison's disease (AD) increased rapidly in incidence among Standard Poodles after the mid-twentieth century. Previous attempts to identify specific genetic causes using genome wide...