Demography and disorders of German Shepherd Dogs under primary veterinary care in the UK [0.03%]
英国宠物医院德国牧羊犬种群及其疾病状况调查
Dan G ONeill,Noel R Coulson,David B Church et al.
Dan G ONeill et al.
Background: The German Shepherd Dog (GSD) has been widely used for a variety of working roles. However, concerns for the health and welfare of the GSD have been widely aired and there is evidence that breed numbers are no...
Corneal ulcerative disease in dogs under primary veterinary care in England: epidemiology and clinical management [0.03%]
英国初诊兽医护理下的犬角膜溃疡病的流行病学和临床管理
Dan G ONeill,Monica M Lee,Dave C Brodbelt et al.
Dan G ONeill et al.
Background: Corneal ulcerative disease (CUD) has the potential to adversely affect animal welfare by interfering with vision and causing pain. The study aimed to investigate for the first time the prevalence, breed-based ...
Janelle M Belanger,Thomas P Bellumori,Danika L Bannasch et al.
Janelle M Belanger et al.
Background: Gonadectomy, or neutering, is a very common surgery for dogs having many positive effects on behavior, health, and longevity. There are also certain risks associated with neutering including the development of...
Mark J Fealey,Joy Li,Rebel J E Todhunter et al.
Mark J Fealey et al.
Background: Concentrated breeding effort to produce various body structures and behaviors of dogs to suit human demand has inadvertently produced unwanted traits and diseases that accompany the morphological and behaviora...
Osteosarcoma inheritance in two families of Scottish deerhounds [0.03%]
苏格兰 Deerhound 犬种中两个家族的骨肉瘤遗传性研究
John E Dillberger,Sara Ann McAtee
John E Dillberger
Background: Osteosarcoma is the most common neoplastic disease in Scottish Deerhounds. For Deerhounds, a 2007 population-based study concluded that a single dominant genetic factor largely governed disease risk. For Greyh...
DNM1 mutation status, sex, and sterilization status of a cohort of Labrador retrievers with and without cranial cruciate ligament rupture [0.03%]
DMN1基因状态、性别和绝育状况对拉布拉多犬后交叉韧带断裂的影响
Kari J Ekenstedt,Katie M Minor,Aaron K Rendahl et al.
Kari J Ekenstedt et al.
Background: Exercise-induced collapse (EIC) due to DNM1 mutation and rupture of the cranial cruciate ligament are both common syndromes in the Labrador retriever breed. A cohort of 313 Labradors was recruited based on the...
Polymorphisms in the canine monoamine oxidase a (MAOA) gene: identification and variation among five broad dog breed groups [0.03%]
犬单胺氧化酶a(MAOA)基因的多态性:五种广义犬品种群体中的识别与变异
James Sacco,Andrew Ruplin,Paul Skonieczny et al.
James Sacco et al.
Background: In humans, reduced activity of the enzyme monoamine oxidase type A (MAOA) due to genetic polymorphisms within the MAOA gene leads to increased brain neurotransmitter levels associated with aggression. In order...
No evidence of prenatal diversifying selection at locus or supertype levels in the dog MHC class II loci [0.03%]
犬MHCⅡ类基因座不存在胚胎分散选择的证据
Alina K Niskanen,Lorna J Kennedy,Hannes Lohi et al.
Alina K Niskanen et al.
Background: Despite decades of studying, the mechanisms maintaining high diversity in the genes of the Major Histocompatibility Complex (MHC) are still puzzling scientists. In addition to pathogen recognition and other fu...
DachsLife 2015: an investigation of lifestyle associations with the risk of intervertebral disc disease in Dachshunds [0.03%]
达克斯犬的生活方式与椎间盘疾病风险的相关性研究——DachsLife 2015项目
R M A Packer,I J Seath,D G ONeill et al.
R M A Packer et al.
Background: Intervertebral disc disease (IVDD) represents a major problem in the Dachshund, with at a relative risk of IVDD 10-12 times higher than other breeds, and an estimated 19-24 % of Dachshunds showing clinical sig...
Niels C Pedersen,Ashley S Pooch,Hongwei Liu
Niels C Pedersen
Background: This study examines genetic diversity among 102 registered English Bulldogs used for breeding based on maternal and paternal haplotypes, allele frequencies in 33 highly polymorphic short tandem repeat (STR) lo...