Oxaliplatin-containing adjuvant chemotherapy improves the survival of locally advanced rectal cancer patients with pathological complete response after pre-operative chemoradiotherapy [0.03%]
新辅助放化疗后病理完全缓解的局部晚期直肠癌患者辅助化疗中含奥沙利铂可提高患者生存率
Jian-Hong Peng,Jun-Zhong Lin,Yu-Ming Rong et al.
Jian-Hong Peng et al.
Background: The necessity for adjuvant chemotherapy (ACT) in locally advanced rectal cancer (LARC) patients who achieve pathological complete response (pCR) after pre-operative chemoradiotherapy (CRT) is still not identif...
Incidence and risk factors for incisional surgical site infection in patients with Crohn's disease undergoing bowel resection [0.03%]
克罗恩病肠切除术后切口部位手术感染的发病情况及影响因素分析
Tuo Hu,Xianrui Wu,Jiancong Hu et al.
Tuo Hu et al.
Background: Patients with Crohn's disease (CD) are often reported to be at a high risk for incisional surgical site infection (SSI). The aim of this study was to identify the risk factors associated with post-operative in...
Freeha Khan,Xian-Hua Gao,Amandeep Singh et al.
Freeha Khan et al.
Background: Our recent study showed the efficacy and safety of vedolizumab in the treatment of chronic antibiotic-refractory pouchitis. However, there are no published studies on its efficacy and safety in Crohn's disease...
Gender, medication use and other factors associated with esophageal motility disorders in non-obstructive dysphagia [0.03%]
与非梗阻性吞咽困难有关的食管运动功能障碍的性别、药物使用及其他因素
Afrin Kamal,Sampurna Shakya,Rocio Lopez et al.
Afrin Kamal et al.
Background: High-resolution esophageal manometry (HREM) is the diagnostic test of choice for evaluation of non-obstructive dysphagia. Studies regarding the predictors of esophageal dysmotility are limited. Therefore, our ...
Inflammatory caspase-related pyroptosis: mechanism, regulation and therapeutic potential for inflammatory bowel disease [0.03%]
与炎症性肠病相关的炎性caspase介导的焦亡：机制、调控及其潜在治疗作用
Yuan-Yuan Yuan,Ke-Xin Xie,Sha-Long Wang et al.
Yuan-Yuan Yuan et al.
As an essential part of programmed cell death, pyroptosis is an inflammatory response that is elicited upon infection by intracellular pathogens. Metabolic diseases, atherosclerosis and vital organ damage occur if pyroptosis is over-activat...
Alexander W W Brown,Robert B Wilson
Alexander W W Brown
Clostridium difficile is a major cause of hospital-associated diarrhoea, and in severe cases leads to pseudomembranous colitis and toxic megacolon. The frequency of C. difficile infection (CDI) has increased in recent decades, with 453 000 ...
Male gender is associated with an increased risk of anastomotic leak in rectal cancer patients after total mesorectal excision [0.03%]
男性性别与经全直肠系膜切除术后直肠癌患者吻合口漏风险增加有关
Chi Zhou,Xian-Rui Wu,Xuan-Hui Liu et al.
Chi Zhou et al.
Background: The impact of a patient's gender on the development of anastomotic leak (AL) in rectal cancer patients following total mesorectal excision (TME) remains controversial. The aim of this study was to evaluate the...
Screening for colorectal cancer in Tianhe, Guangzhou: results of combining fecal immunochemical tests and risk factors for selecting patients requiring colonoscopy [0.03%]
广州天河区结直肠癌筛查：联合粪便免疫化学法和风险因素选择需要进行肠镜检查的患者的效果分析
Yi Liao,Senmao Li,Chunyu Chen et al.
Yi Liao et al.
Objective: To explore the performance of a protocol combining fecal immunochemical test (FIT) and a high-risk factor questionnaire (HRFQ) for selecting patients requiring colonoscopy as part of a population-based colorect...
A comparison of APACHE II, BISAP, Ranson's score and modified CTSI in predicting the severity of acute pancreatitis based on the 2012 revised Atlanta Classification [0.03%]
基于亚特兰大2012年修订版分类的急性胰腺炎严重程度评估体系的比较研究(APACHE II,BISAP,Ranson及改良CTSI)
Anubhav Harshit Kumar,Mahavir Singh Griwan
Anubhav Harshit Kumar
Objective: Our aim was to prospectively compare the Accuracy of Acute Physiology and Chronic Health Evaluation (APACHE) II, Bedside Index of Severity in Acute Pancreatitis (BISAP), Ranson's score and modified Computed Tom...
Fluoroscopic gastric peroral endoscopic pyloromyotomy (G-POEM) in patients with a failed gastric electrical stimulator [0.03%]
胃电刺激失败患者的胃镜下幽门肌切开术(G-POEM)的透视研究
Abhinav Koul,Sunil Dacha,Parit Mekaroonkamol et al.
Abhinav Koul et al.
Background: Gastric electrical stimulators (GESs) have been used to treat refractory gastroparesis in patients who fail initial therapies such as dietary modifications, control of psychological stressors and pharmacologic...