The safety of esophagojejunostomy via a transorally inserted-anvil method vs extracorporeal anastomosis using a circular stapler during total gastrectomy for Siewert type 2 adenocarcinoma of the esophagogastric junction [0.03%]
经食管胃空肠吻合术腔内荷包技术相对于食管胃结合部Siewert II型腺癌全胃切除术后 extraluminal 吻合的吻合口安全性研究
Xin-Hua Chen,Yan-Feng Hu,Jun Luo et al.
Xin-Hua Chen et al.
Background: Intracorporeal esophagojejunostomy via a transorally inserted-anvil method during laparoscopic total gastrectomy (LTG) for upper gastric cancer has been demonstrated to be feasible, but the use of this assessm...
Nomogram for predicting pathological complete response and tumor downstaging in patients with locally advanced rectal cancer on the basis of a randomized clinical trial [0.03%]
基于随机临床试验的局部晚期直肠癌病理性完全缓解和肿瘤降期的预测列线图
Jian-Wei Zhang,Yue Cai,Xiao-Yu Xie et al.
Jian-Wei Zhang et al.
Background: Preoperative fluoropyrimidine with radiotherapy was regarded as the standard of care for locally advanced rectal cancer (LARC). The model for predicting pCR in LARC patients was based on standard treatment onl...
Culture and application of conditionally reprogrammed primary tumor cells [0.03%]
条件性重组原发肿瘤细胞培养体系的建立及应用
Mengjun Zhong,Liwu Fu
Mengjun Zhong
Cancer is still a major public-health problem that threatens human life worldwide and further study needs to be carried out in the basic and preclinical areas. Although high-throughput sequencing technology and individualized precise therap...
The influence of mitochondrial-directed regulation of Wnt signaling on tumorigenesis [0.03%]
线粒体调节Wnt信号对肿瘤发生的影响
Yaritza Delgado-Deida,Kibrom M Alula,Arianne L Theiss
Yaritza Delgado-Deida
Mitochondria are dynamic organelles that play a key role in integrating cellular signaling. Mitochondrial alterations are evident in all stages of tumorigenesis and targeting mitochondrial pathways has emerged as an anticancer therapeutic s...
Influence of microbiota on immunity and immunotherapy for gastric and esophageal cancers [0.03%]
胃癌及食管癌的微生物群免疫影响及其免疫治疗反应
Xiaoli Zhang,Zui Pan
Xiaoli Zhang
Gastric and esophageal cancers are multifactorial and multistage-involved malignancy. While the impact of gut microbiota on overall human health and diseases has been well documented, the influence of gastric and esophageal microbiota on ga...
BRAF and KRAS mutations in metastatic colorectal cancer: future perspectives for personalized therapy [0.03%]
转移性结直肠癌中BRAF和KRAS基因突变的未来个性化治疗展望
Zi-Nan Li,Lin Zhao,Li-Feng Yu et al.
Zi-Nan Li et al.
Colorectal cancer (CRC) is one of the most commonly diagnosed cancers worldwide and 30% of patients with CRC experience metastasis. Patients with metastatic colorectal cancer (mCRC) have a 5-year overall survival rate of
Anti-EGFR therapy in metastatic colorectal cancer: mechanisms and potential regimens of drug resistance [0.03%]
抗表皮生长因子受体治疗转移性结直肠癌的机制及药物耐药的潜在逆转方案
Qing-Hai Li,Ying-Zhao Wang,Jian Tu et al.
Qing-Hai Li et al.
Cetuximab and panitumumab, as the highly effective antibodies targeting epidermal growth factor receptor (EGFR), have clinical activity in the patients with metastatic colorectal cancer (mCRC). These agents have good curative efficacy, but ...
Liwu Fu
Liwu Fu
Strategies for the management of gastrointestinal surgery in the COVID-19 pandemic [0.03%]
新冠肺炎疫情下的胃肠外科手术管理策略
Steven D Wexner
Steven D Wexner
Strategies and recommendations for the management of gastrointestinal surgery during the COVID-19 pandemic: experience shared by Chinese surgeons [0.03%]
新冠肺炎疫情期间中国普外科医师分享的胃肠手术诊疗策略和建议
Jia Ke,Nan Lan,Ting Wang et al.
Jia Ke et al.
Novel coronavirus disease-2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is an ongoing public-health pandemic worldwide. Although SARS-CoV-2 has been known to spread primarily through respiratory dr...