Medically tailored meals for the management of symptomatic ascites: the SALTYFOOD pilot randomized clinical trial [0.03%]
针对腹水症状管理的医疗定制餐食：SALTYFOOD 预防试验随机临床试验
Elliot B Tapper,Jad Baki,Samantha Nikirk et al.
Elliot B Tapper et al.
Background: Ascites is a costly, morbid complication of cirrhosis. Although a low-sodium diet is central to the clinical management of ascites, its efficacy is limited by poor adherence. We aimed to determine the feasibil...
Density and distribution of lymphocytes in pretherapeutic rectal cancer and response to neoadjuvant therapy [0.03%]
新辅助治疗前直肠癌淋巴细胞密度和分布与疗效的关系研究
Sicong Lai,Xiaoying Lou,Xinjuan Fan et al.
Sicong Lai et al.
Background: Lymphocytic density in rectal cancer has been reported to be associated with therapeutic response, but the role of the lymphocytic distribution pattern remains to be determined. This study aimed to evaluate th...
NUDT15 genotyping during azathioprine treatment in patients with inflammatory bowel disease: implications for a dose-optimization strategy [0.03%]
炎症性肠病患者接受硫唑嘌呤治疗期间进行NUDT15基因分型对剂量优化策略的意义
Ye Xu,Yu-Qi Qiao,Han-Yang Li et al.
Ye Xu et al.
Background: NUDT15 R139C is an Asian-prevalent genetic variant related to azathioprine (AZA) intolerance in patients with inflammatory bowel disease (IBD). However, it remains unclear how to utilize the genotyping results...
The SAFE-T upper endoscopy tool: a web-based application for the point-of-care evaluation of gastroenterology fellow performance in upper endoscopy [0.03%]
一种评估胃肠病学住院医师上消化道内镜操作表现的床旁评价工具：SAFE-T上消化道内镜操作评估网络应用系统
Navin L Kumar,Guillaume Kugener,Kelly E Hathorn et al.
Navin L Kumar et al.
Background: Attending assessment is a critical part of endoscopic education for gastroenterology fellows. The aim of this study was to develop and validate a concise, web-based assessment tool to evaluate real-time fellow...
Outcomes of a single-step endoscopic ultrasound-guided drainage of pancreatic-fluid collections using an electrocautery-enhanced coaxial lumen-apposing, self-expanding metal stent with and without fluoroscopy [0.03%]
带有和不带荧光透视的单步内镜超声引导下使用电刀增强同轴腔道金属支架引流胰腺液性占位的临床疗效研究
Babatunde Olaiya,Parit Mekaroonkamol,Bai-Wen Li et al.
Babatunde Olaiya et al.
Background: Fluoroscopy is often used during the endoscopic drainage of pancreatic-fluid collections (PFCs). An electrocautery-enhanced coaxial lumen-apposing, self-expanding metal stent (ELAMS) facilitates a single-step ...
Transcriptomic biomarkers for predicting response to neoadjuvant treatment in oesophageal cancer [0.03%]
食管癌新辅助治疗反应预测的转录标志物研究
Anita Lavery,Richard C Turkington
Anita Lavery
Oesophageal cancer is a devastating disease with poor outcomes and is the sixth leading cause of cancer death worldwide. In the setting of resectable disease, there is clear evidence that neoadjuvant chemotherapy and chemoradiotherapy resul...
Antibiotic prophylaxis and infectious complications in patients on peritoneal dialysis undergoing lower gastrointestinal endoscopy [0.03%]
腹膜透析患者行结肠镜检查的抗菌药物预防及感染并发症研究
William T Clarke,Venkata R Satyam,David I Fudman et al.
William T Clarke et al.
Low prevalence of mismatch repair deficiency in Chinese colorectal cancers: a multicenter study [0.03%]
中国结直肠癌错配修复缺陷的低突变率及林奇综合征患病率的多中心研究
Wu Jiang,Qiao-Qi Sui,Wen-Liang Li et al.
Wu Jiang et al.
Background: Although universal testing for mismatch repair deficiency (dMMR) has been recommended to all colorectal cancer (CRC) patients, related evidence for the Chinese population is lacking. Here, we investigated the ...
Upregulation of PD-L1 expression promotes epithelial-to-mesenchymal transition in sorafenib-resistant hepatocellular carcinoma cells [0.03%]
PD-L1表达上调可通过促进上皮间质转化作用诱导索拉非尼耐药的肝癌细胞
Gui-Li Xu,Cai-Fang Ni,Han-Si Liang et al.
Gui-Li Xu et al.
Background: The epithelial-to-mesenchymal transition (EMT) status is associated with programmed death-1 ligand 1 (PD-L1) expression in various cancers. However, the role and molecular mechanism of PD-L1 in the EMT of sora...
The tumor immune microenvironment transcriptomic subtypes of colorectal cancer for prognosis and development of precise immunotherapy [0.03%]
结直肠癌肿瘤免疫微环境转录亚型的预后及精准免疫治疗发展研究
Yun-Qiang Tang,Tu-Feng Chen,Yan Zhang et al.
Yun-Qiang Tang et al.
Background: Biomarkers based on immune context may guide prognosis prediction. T-cell inactivation, exclusion, or dysfunction could cause unfavorable tumor microenvironments, which affect immunotherapy and prognosis. Howe...