Associations between androgen levels and endurance training-induced changes in body composition and physical performance in premenopausal females [0.03%]
雄激素水平与经绝经前女性耐力训练诱导的身体组成和体能变化之间的关系
Vera M Salmi,Jari E Karppinen,Maarit Lehti et al.
Vera M Salmi et al.
We investigated whether a moderate-intensity continuous training (MICT) for two menstrual/contraceptive cycles (~8 weeks) alters endogenous androgen concentrations in premenopausal females, and whether baseline androgen concentrations or th...
High-fat diet attenuates estradiol's efficacy on cognitive function and hippocampal synaptic plasticity in middle-aged ovariectomized mice [0.03%]
高脂饮食可减弱17β-雌二醇对中年卵巢切除小鼠认知功能及海马突触可塑性的影响
V Felintro,L D Desmoulins,C M Dugas et al.
V Felintro et al.
Loss of circulating ovarian hormones during menopause is associated with increased risk for cognitive decline in women. Although estradiol has been shown to enhance memory and synaptic function in preclinical studies, clinical studies of ho...
Mechanism of paraventricular nucleus H2S on PERK/TXNIP/NLRP3 pathway in male spontaneously hypertensive rats [0.03%]
内源性H2S通过PARV利钠肽PERK/TXNIP/NLRP3通路改善高血压大鼠胰岛素抵抗的作用及机制研究
Yan-Feng Liang,Shu-Yue Chen,Hui Wang et al.
Yan-Feng Liang et al.
Hydrogen sulfide (H2S) exhibits anti-inflammatory, anti-apoptotic, and antioxidant effects. However, the central nervous system regulatory mechanisms of H2S in hypertension remain unclear. This study aimed to investigate the regulatory effe...
Effects of prior heavy exercise on deoxygenation in deep versus superficial muscle regions during subsequent heavy exercise in adult males [0.03%]
先前进行高强度运动对之后高强度运动中成人男性深肌层和浅肌层脱氧作用的影响
Weerapong Chidnok,Dai Okushima,Richie P Goulding et al.
Weerapong Chidnok et al.
We assessed the effects of prior heavy-intensity-exercise (PHE) on microvascular deoxygenation in deep vastus lateralis muscle (VLd) compared with the superficial VL (VLs). Thirteen subjects completed two 6-min bouts of heavy exercise, sepa...
Models of the human heart for biomedical research: Opportunities and challenges [0.03%]
用于生物医学研究的人类心脏模型：机遇与挑战
Katrin Streckfuss-Bömeke,Laura C Zelarayán,Renate B Schnabel et al.
Katrin Streckfuss-Bömeke et al.
Model systems that mimic human cardiac structure and function are essential for the development of novel diagnostics and effective treatments for cardiovascular diseases. While non-human vertebrate models, from zebrafish to pig, remain vita...
Effects of vagal nerve stimulation on pain frequency and intensity in chronic migraine in adults: A randomized controlled trial [0.03%]
迷走神经刺激对成人慢性偏头痛疼痛频率和强度的影响：一项随机对照试验
Rabia Nasir,Mirza Obaid Baig,Turki Abualait et al.
Rabia Nasir et al.
To determine the effects of noninvasive vagal nerve stimulation (nVNS) on the frequency, intensity, impact, and quality of life in individuals with chronic migraine. The randomized controlled trial (RCT) was conducted over 128 participants,...
Randomized Controlled Trial
Physiological reports. 2026 Apr;14(7):e70843. DOI:10.14814/phy2.70843 2026
Cell-cycle regulation of sarcomere integrity-Role for Actn2 phosphorylation [0.03%]
细胞周期对肌节完整性的作用-ACTN2磷酸化的功能
S S Baksh,I Anwar,X Wang et al.
S S Baksh et al.
Sarcomeres are the fundamental contractile units of muscle. Despite their importance, sarcomere assembly remains poorly understood. We focused on Actn2, a protein which stabilizes the sarcomere by linking proteins to the Z-disk. During C2C1...
Cold exposure and metabolic health: Therapeutic potential for obesity, diabetes, and beyond [0.03%]
冷暴露与代谢健康：肥胖、糖尿病等疾病的治疗潜力
Xirong Li,Jiale Dang,Rui Guo et al.
Xirong Li et al.
Cold exposure, an inducer of brown adipose tissue thermogenesis, has been applied to relieve exercise-induced pain and inflammation, modulate circulation and enhance metabolism. However, its role in managing metabolic diseases and the under...
Return to an extreme environment exposure after pulmonary infection: SCUBA diving as a model? [0.03%]
潜水后的极端环境暴露会对肺部感染产生什么影响？
Danilo Cialoni,Andrea Brizzolari,Simona Mrakic-Sposta et al.
Danilo Cialoni et al.
The human body implements several adaptive mechanisms to perform in extreme environments. Increasingly, individuals return to such conditions after pulmonary infections, raising concerns about potential long-term respiratory consequences. T...
Biological sex influences bilateral transcortical reflexes during unilateral upper extremity exercise in healthy adults [0.03%]
健康成人单侧上肢运动时性别对双边皮质反射的影响
Olga Dubey,Michael A Petrie,Richard K Shields
Olga Dubey
The transcortical long-latency reflex (LLR) is a rapid feedback response that is thought to help stabilize movement following sudden disturbances and is a critical mechanism enabling precise upper limb control during unexpected perturbation...