Improvements in vertical jump by healthy adults at high altitude despite inter-individual differences in neuromuscular coordination changes [0.03%]
健康成人尽管神经肌肉协调变化的个体差异较大,但在高海拔地区垂直跳跃仍有所提高
Michele DAttilio,Riccardo Rua,Alberto Taverna et al.
Michele DAttilio et al.
Research indicates that the performance is enhanced in situations involving rapid movements at high altitude. However, maintaining equilibrium and walking economically in low-oxygen conditions are often impaired. The objective of this study...
Are saliva and bile sources of oxalate secretion into the human gastrointestinal tract? [0.03%]
唾液和胆汁是人体消化道草酸分泌的来源吗?
Emma Earhart,Thomas Tielleman,John Knight et al.
Emma Earhart et al.
Elevated urine oxalate (hyperoxaluria) is a risk factor for kidney stones. Normally eliminated by the kidneys, oxalate originates from endogenous metabolism and dietary absorption but secretion into the intestine remains an open question. W...
Integrative bioinformatic analysis identifies an extracellular matrix gene signature linked to muscle adaptation to endurance and resistance training [0.03%]
整合生物信息学分析发现与肌肉耐力和阻力训练适应性相关的细胞外基质基因标志物
Muhammad Isman Sandira,Firman Hasan,Tsubasa Shibaguchi et al.
Muhammad Isman Sandira et al.
Skeletal muscle exhibits a remarkable adaptive capacity; endurance training enhances mitochondrial capacity, whereas resistance training improves mechanical strength. Despite these differences, both training impose repeated contractile and ...
Ronald F Coburn,Michael S Tift
Ronald F Coburn
An understanding of the physiology of acute carbon monoxide (CO) poisoning remains incomplete. This study describes a novel approach-considering a CO cycle driven by CO inhalation which includes: alveolar CO uptake → the transport to perip...
Sex-specific relation of replacing sedentary time with physical activity on stage 2 hypertension incidence in middle-aged adults [0.03%]
用体力活动代替久坐与中年人2级高血压发病的关系性别差异研究
Sophie E Rayner,Jolaine Katryne Bossé,Corinne Brideau et al.
Sophie E Rayner et al.
Hypertension is increasingly prevalent among middle-aged adults, but the impacts of physical activity and postures are not fully understood in middle-aged males and females, limiting targeted prevention. This study investigated associations...
Brachial blood flow and pressure responses are unrelated to the greater isometric handgrip tolerance of females compared to males [0.03%]
女性的肱动脉血流和血压反应与其与男性相比更大的等长握力耐受性无关
João L Marôco,Joseph Scangas,Megan Borges et al.
João L Marôco et al.
Isometric handgrip (IHG) training lowers blood pressure (BP), but sex differences in fatigability may be confounding. We hypothesized that the greater time-to-fatigue during IHG in females would relate to preserved brachial blood flow, with...
Sex-dependent effects of environmental enrichment on mood-related behaviors, central and peripheral BDNF, and adrenal catecholamine enzymes in mice [0.03%]
环境丰富对小鼠情绪行为、中枢和外周BDNF及肾上腺儿茶酚胺酶的性别差异效应
M F Herselman,S Y Luo,L Y Lin et al.
M F Herselman et al.
Housing conditions, particularly environmental enrichment (EE), can influence experimental outcomes and welfare. While EE is generally regarded as beneficial, a male bias exists in research supporting this. This study investigated whether s...
Circulating elastin crosslinking desmosines are associated with arterial wall degradation in older adults with atherosclerosis [0.03%]
血浆弹性蛋白交联物脱氨基ines与老年人动脉粥样硬化相关的动脉壁退行性改变有关
Hana Inoue,Lisa Takahashi,Hirofumi Tomiyama et al.
Hana Inoue et al.
Elastin, an extracellular matrix component that contributes to vascular integrity, is progressively degraded during vascular injury including atherosclerosis. We assessed circulating desmosine (DES) and isodesmosine (IDES), elastin-specific...
Mature-onset obesity in p62-deficient male mice maintains skeletal muscle mass despite metabolic dysfunction [0.03%]
p62缺陷小鼠成熟期肥胖不影响其肌肉量
Do-Houn Kim,Gloria Salazar,Alex Klemp et al.
Do-Houn Kim et al.
Sequestosome 1 (p62/SQSTM1) is a multifunctional scaffolding protein at the intersection of autophagy and metabolic regulation. While p62 deficiency causes mature-onset obesity and insulin resistance, its effects on skeletal muscle mass and...