Katherine Wander,Olayinka O Ogunleye,Evelyn N Nwagu et al.
Katherine Wander et al.
Background and objectives: The optimal iron hypothesis (OIH) posits that risk for infection is lowest at a mild level of iron deficiency. The extent to which this protection results from arms race dynamics in the evolutio...
Reverse-engineering the Venus figurines: An eco-life-course hypothesis for the aetiology of obesity in the Palaeolithic [0.03%]
逆向解读维纳斯雕像：旧石器时代肥胖症致病原因的生态生命周期假说
Jonathan C K Wells,Frank L&#x;Engle Williams,Gernot Desoye
Jonathan C K Wells
Evolutionary perspectives on obesity have been dominated by genetic frameworks, but plastic responses are also central to its aetiology. While often considered a relatively modern phenomenon, obesity was recorded during the Palaeolithic thr...
Towards a new therapeutic approach based on selection for function in tumors: response to Dr. Mesut Tez [0.03%]
基于肿瘤功能选择的新治疗策略的研究进展：回应梅苏特·特兹博士的意见
Frédéric Thomas,James DeGregori,Andriy Marusyk et al.
Frédéric Thomas et al.
C Ruth Archer,Meaghan Castledine,David J Hosken
C Ruth Archer
Many postpartum women experience sexual dysfunction, characterised by reduced sexual motivation and libido, and pain during intercourse. Menstruation is also suppressed in breastfeeding women (lactational amenorrhoea). Lactational amenorrho...
Lev Kolinski,Tyler M Barrett,Randall A Kramer et al.
Lev Kolinski et al.
Market integration (MI), or the shift from subsistence to market-based livelihoods, profoundly influences health, yet its impacts on infectious diseases remain underexplored. Here, we synthesize the current understanding of MI and infectiou...
Mesut Tez
Mesut Tez
Integrating the Thrifty Genotype and Evolutionary Mismatch Hypotheses to understand variation in cardiometabolic disease risk [0.03%]
整合节俭基因假说和进化不适配假说以理解心血管代谢疾病风险的差异性
Layla Brassington,Audrey M Arner,Marina M Watowich et al.
Layla Brassington et al.
More than 60 years ago, James Neel proposed the Thrifty Genotype Hypothesis to explain the widespread prevalence of type 2 diabetes in Western, industrial contexts. This hypothesis posits that variants linked to conservative energy usage an...
Lonely, stressed-out moms: Does the postindustrial social experience put women at risk for perinatal mood disorders? [0.03%]
孤独而压力山大的妈妈们：后工业社会体验会让女性在围产期出现情绪障碍吗？
Elena Bridgers,Molly M Fox
Elena Bridgers
Perinatal mood and anxiety disorders (PMADs) are estimated to affect as many as 17.7% of mothers in agricultural and postindustrial societies. Various lines of research converge to suggest that PMADs may be 'diseases of modernity', arising ...
Low haemoglobin in arduous seasons is associated with reduced chance of ovulation among women living in the Bolivian altiplano [0.03%]
玻利维亚高原地区艰难时节低血红蛋白与女性排卵机会减少有关
Rose Stevens,Alexandra Alvergne,Virginia J Vitzthum
Rose Stevens
Background and objectives: Female reproductive function flexibly responds to ecological variation in energy availability, but the roles of other ecologically limited resources, such as iron, remain poorly understood. This...
Phenome-wide association study of population-differentiating genetic variants around gene ACSL1 [0.03%]
ACSL1基因周围区分人群的变异的全表型组关联研究
Shuang Yang,Houjian Cai,Kaixiong Ye
Shuang Yang
Background and objectives: Demographic dynamics and natural selection during human evolution shaped the present-day patterns of genetic variations, and geographically varying genetic factors contribute to different diseas...