African variation at Cytochrome P450 genes: Evolutionary aspects and the implications for the treatment of infectious diseases [0.03%]
非洲CYP基因多态性：进化特点及其对治疗传染病的影响
Ripudaman K Bains
Ripudaman K Bains
The genomics revolution has provided a plethora of data from many previously uncharacterized populations. The increase in the amount of genetic data has improved our understanding of why individuals and populations differ in their susceptib...
Testing the evolutionary basis of the predictive adaptive response hypothesis in a preindustrial human population [0.03%]
检验预测性适应反应假说的进化基础的一个前工业人类群体的例子
Adam D Hayward,Virpi Lummaa
Adam D Hayward
Background and objectives: The thrifty phenotype hypothesis proposes that late-life metabolic diseases result from mismatch between early-life and adulthood nutrition. More recently, the predictive adaptive response (PAR)...
Maxine Weinstein
Maxine Weinstein
Evolutionary biology and anthropology suggest biome reconstitution as a necessary approach toward dealing with immune disorders [0.03%]
进化生物学和人类学表明生物重构是应对免疫紊乱的一种必要方法
William Parker,Jeff Ollerton
William Parker
Industrialized society currently faces a wide range of non-infectious, immune-related pandemics. These pandemics include a variety of autoimmune, inflammatory and allergic diseases that are often associated with common environmental trigger...
Fernando Baquero
Fernando Baquero
The adolescent transition under energetic stress: Body composition tradeoffs among adolescent women in The Gambia [0.03%]
营养压力下的青春期过渡：冈比亚青春期女性的身体组成取舍
Meredith W Reiches,Sophie E Moore,Andrew M Prentice et al.
Meredith W Reiches et al.
Background and objectives: Life history theory predicts a shift in energy allocation from growth to reproductive function as a consequence of puberty. During adolescence, linear growth tapers off and, in females, ovarian ...
Epistasis between antibiotic resistance mutations drives the evolution of extensively drug-resistant tuberculosis [0.03%]
抗生素耐药性突变之间的基因互作驱动广泛获得药物抗性的结核杆菌的进化
Sònia Borrell,Youjin Teo,Federica Giardina et al.
Sònia Borrell et al.
Background and objectives: Multidrug resistant (MDR) bacteria are a growing threat to global health. Studies focusing on single antibiotics have shown that drug resistance is often associated with a fitness cost in the ab...
Graham A W Rook,Christopher A Lowry,Charles L Raison
Graham A W Rook
Chronic inflammatory diseases (autoimmunity, allergy and inflammatory bowel diseases) are increasing in prevalence in urban communities in high-income countries. One important factor is reduced exposure to immunoregulation-inducing macro- a...
Socioeconomic status determines sex-dependent survival of human offspring [0.03%]
经济社会地位决定人类后代的性别依赖生存率
David van Bodegom,Maarten P Rozing,Linda May et al.
David van Bodegom et al.
Background and objectives: In polygynous societies, rich men have many offspring through the marriage of multiple wives. Evolutionary, rich households would therefore benefit more from sons, and according to the Trivers-W...
Identifying future zoonotic disease threats: Where are the gaps in our understanding of primate infectious diseases? [0.03%]
识别未来人畜共患病威胁：我们对于灵长类动物感染性疾病的了解存在哪些空白？
Natalie Cooper,Charles L Nunn
Natalie Cooper
Background and objectives: Emerging infectious diseases often originate in wildlife, making it important to identify infectious agents in wild populations. It is widely acknowledged that wild animals are incompletely samp...