Genetic links between post-reproductive lifespan and family size in Framingham [0.03%]
遗传联系：弗雷明汉研究中后生殖寿命和家庭规模的关系
Xiaofei Wang,Sean G Byars,Stephen C Stearns
Xiaofei Wang
Background and objectives: Is there a trade-off between children ever born (CEB) and post-reproductive lifespan in humans? Here, we report a comprehensive analysis of reproductive trade-offs in the Framingham Heart Study ...
Genome organization and the role of centromeres in evolution of the erythroleukaemia cell line HEL [0.03%]
基因组组织和着丝粒在红白血病细胞系HEL进化中的作用
Ruth N Mackinnon,Meaghan Wall,Adrian Zordan et al.
Ruth N Mackinnon et al.
Background and objectives: The human erythroleukaemia (HEL) cell line has a highly rearranged genome. We matched whole chromosome analysis with cytogenomic microarray data to build a detailed description of these rearrang...
How effectively can HIV phylogenies be used to measure heritability? [0.03%]
HIV系统发育树在测量遗传率方面能有多大的作用？
George Shirreff,Samuel Alizon,Anne Cori et al.
George Shirreff et al.
Background and objectives: The severity of HIV-1 infection, measured by set-point viral load (SPVL), is highly variable between individuals. Its heritability between infections quantifies the control the pathogen genotype...
Stephen C Stearns
Stephen C Stearns
James J Bull,Michael Turelli
James J Bull
A novel form of biological control is being applied to the dengue virus. The agent is the maternally transmitted bacterium Wolbachia, naturally absent from the main dengue vector, the mosquito Aedes aegypti. Three Wolbachia-based control st...
Patterns of physical and psychological development in future teenage mothers [0.03%]
未来少女母亲的身体和心理发展特征模式分析
Daniel Nettle,Thomas E Dickins,David A Coall et al.
Daniel Nettle et al.
Background and objectives: Teenage childbearing may have childhood origins and can be viewed as the outcome of a coherent reproductive strategy associated with early environmental conditions. Life-history theory would pre...
Hygiene and the world distribution of Alzheimer's disease: Epidemiological evidence for a relationship between microbial environment and age-adjusted disease burden [0.03%]
卫生与阿尔茨海默病的全球分布：关于微生物环境和年龄调整后的疾病负担之间的关系的流行病学证据
Molly Fox,Leslie A Knapp,Paul W Andrews et al.
Molly Fox et al.
Background and objectives: Alzheimer's disease (AD) shares certain etiological features with autoimmunity. Prevalence of autoimmunity varies between populations in accordance with variation in environmental microbial dive...
Evolutionarily stable anti-cancer therapies by autologous cell defection [0.03%]
利用自体细胞缺陷实现进化稳定的抗癌疗法
Marco Archetti
Marco Archetti
Game theory suggests an anti-cancer treatment based on the use of modified cancer cells that disrupt cooperation within the tumor. Cancer cells are harvested from the patient, the genes for the production of essential growth factors are kno...
Evidence for gene duplication in the voltage-gated sodium channel gene of Aedes aegypti [0.03%]
蚊子电压门控钠通道基因复制的证据
Ademir Jesus Martins,Luiz Paulo Brito,Jutta Gerlinde Birggitt Linss et al.
Ademir Jesus Martins et al.
Background and objectives: Mutations in the voltage-gated sodium channel gene (NaV), known as kdr mutations, are associated with pyrethroid and DDT insecticide resistance in a number of species. In the mosquito dengue vec...
Lucy M Carter,Björn F C Kafsack,Manuel Llinás et al.
Lucy M Carter et al.
For vector-borne parasites such as malaria, how within- and between-host processes interact to shape transmission is poorly understood. In the host, malaria parasites replicate asexually but for transmission to occur, specialized sexual sta...