Biomarkers or biotargets? Using competition to lure cancer cells into evolutionary traps [0.03%]
生物标志物还是生物靶点？利用竞争诱使癌细胞陷入进化陷阱
Anuraag Bukkuri,Frederick R Adler
Anuraag Bukkuri
Background and objectives: Cancer biomarkers provide information on the characteristics and extent of cancer progression and help inform clinical decision-making. However, they can also play functional roles in oncogenesi...
Ralph Catalano,Tim A Bruckner,Alison Gemmill et al.
Ralph Catalano et al.
Background and objectives: Selection in utero predicts that population stressors raise the standard for how quickly fetuses must grow to avoid spontaneous abortion. Tests of this prediction must use indirect indicators of...
Low birthweight is associated with epigenetic age acceleration in the first 3 years of life [0.03%]
出生低体重与生命最初三年的表观遗传年龄加速有关
Edward B Quinn,Chu J Hsiao,Felicien M Maisha et al.
Edward B Quinn et al.
Background and objectives: The Developmental Origins of Health and Disease hypothesis posits that early life adversity is associated with poor adult health outcomes. Epidemiological evidence has supported this framework b...
Maternal mental health and economic autonomy in lowland rural Nepal: Do parents-in-law provide constraint or support? [0.03%]
尼泊尔低地农村地区的产妇心理健康和经济自主权：父母是否提供了支持或限制？
Akanksha A Marphatia,Laura K Busert-Sebela,Lu Gram et al.
Akanksha A Marphatia et al.
Background and objectives: In patrilocal societies, married women typically co-reside with their parents-in-law, who may act in their son's reproductive interests. These relationships may shape maternal mental health and ...
Humans can detect axillary odor cues of an acute respiratory infection in others [0.03%]
人类能够感知他人急性呼吸道感染的腋窝气味信号
Arnaud Tognetti,Megan N Williams,Nathalie Lybert et al.
Arnaud Tognetti et al.
Background and objectives: Body odor conveys information about health status to conspecifics and influences approach-avoidance behaviors in animals. Experiments that induce sickness in otherwise healthy individuals sugges...
Double trouble: trypanosomatids with two hosts have lower infection prevalence than single host trypanosomatids [0.03%]
双宿主锥体虫感染率低于单宿主锥体虫
Hawra Al-Ghafli,Seth M Barribeau
Hawra Al-Ghafli
Trypanosomatids are a diverse family of protozoan parasites, some of which cause devastating human and livestock diseases. There are two distinct infection life cycles in trypanosomatids; some species complete their entire life cycle in a s...
Social determinants of health and disease in companion dogs: a cohort study from the Dog Aging Project [0.03%]
来自狗衰老项目的伴侣犬健康和疾病的社交决定因素：队列研究
Brianah M McCoy,Layla Brassington,Kelly Jin et al.
Brianah M McCoy et al.
Exposure to social environmental adversity is associated with health and survival across many social species, including humans. However, little is known about how these health and mortality effects vary across the lifespan and may be differ...
Robert J Woods,Andrew F Read
Robert J Woods
The evolution of antibiotic resistance in an incurable and ultimately fatal infection: A retrospective case study [0.03%]
抗生素耐药性进化的回顾性病例研究：以一种无法治愈的致命感染为例
Robert J Woods,Camilo Barbosa,Laura Koepping et al.
Robert J Woods et al.
Background and objectives: The processes by which pathogens evolve within a host dictate the efficacy of treatment strategies designed to slow antibiotic resistance evolution and influence population-wide resistance level...
D Susie Lee,Hanna Semenchenko
D Susie Lee
Background and objectives: Pubertal timing is a key life history trait with long-term health consequences in both sexes. Evolutionary theory has guided extensive research on developmental influences, in particular growing...