Human induced pluripotent stem cell for modeling cardiovascular diseases [0.03%]
诱导性多能干细胞在心血管疾病中的应用模型
Ping Liang,Jie Du
Ping Liang
The invention of the induced pluripotent stem cell (iPSC) technology allows patient-specific, mature somatic cells to be converted into an unlimited supply of pluripotent stem cells (PSCs). These iPSCs can then in turn be differentiated int...
Ischemic stroke and repair: current trends in research and tissue engineering treatments [0.03%]
缺血性中风及其修复：研究和组织工程治疗的现状
Jian Wang,Wen Yang,Hongjian Xie et al.
Jian Wang et al.
Stroke, the third leading cause of mortality, is usually associated with severe disabilities, high recurrence rate and other poor outcomes. Currently, there are no long-term effective treatments for stroke. Cell and cytokine therapies have ...
Hypothalamic paraventricular nucleus activation contributes to neurohumoral excitation in rats with heart failure [0.03%]
室旁核的激活导致心衰大鼠神经体液兴奋性增高
Yu-Ming Kang,Qing Yang,Xiao-Jing Yu et al.
Yu-Ming Kang et al.
Heart failure (HF) is a serious cardiovascular disease and is characterized by exaggerated sympathetic activity. In this paper, we review these limited studies, with particular emphasis on examining the role of the paraventricular nucleus (...
Lu Cai,Bradley B Keller
Lu Cai
The prevalence of diabetes continues to increase world-wide and is a leading cause of morbidity, mortality, and rapidly rising health care costs. Although strict glucose control combined with good pharmacological and non-pharmacologic inter...
Endothelial progenitor cells in cardiovascular diseases: from biomarker to therapeutic agent [0.03%]
心血管疾病中的内皮祖细胞：从生物标记到治疗试剂
Hui-Bin Liu,Yuan-Feng Gong,Chang-Jiang Yu et al.
Hui-Bin Liu et al.
Regenerative medicine techniques to recover cardiac and vascular function are being increasingly investigated as management strategies for cardiovascular diseases. Circulating endothelial progenitor cells (EPCs) derived from bone marrow are...
Expression of tropomyosin in relation to myofibrillogenesis in axolotl hearts [0.03%]
元古代心肌中肌原纤维发育与横纹肌蛋白的表达关系研究
Robert W Zajdel,Matthew D McLean,Syamalima Dube et al.
Robert W Zajdel et al.
The anatomy, function and embryonic development of the heart have been of interest to clinicians and researchers alike for centuries. A beating heart is one of the key criteria in defining life or death in humans. An understanding of the mu...
Y James Kang,Lily Zheng
Y James Kang
The word "rejuvenate" found in the Merriam-Webster dictionary is (1) to make young or youthful again: give new vigor to, and (2) to restore to an original or new state. Regenerative medicine is the process of creating living, functional tis...
Current status of induced pluripotent stem cells in cardiac tissue regeneration and engineering [0.03%]
诱导多能干细胞在心脏组织再生和工程中的现状
Zhiqiang Liu,Jin Zhou,Haibin Wang et al.
Zhiqiang Liu et al.
Myocardial infarction (MI) is associated with damage to the myocardium which results in a great loss of functional cardiomyocytes. As one of the most terminally differentiated organs, the endogenous regenerative potentials of adult hearts a...
Yi Wang,Chaoshu Tang,Yanwen Qin
Yi Wang
Abdominal aortic aneurysm (AAA) is a fatal disease defined as an abdominal aortic diameter of 3.0 cm or more, where the abdominal aorta exceeds the normal diameter by more than 50%. Histopathological changes of AAA mainly include extracellu...
Restoration versus reconstruction: cellular mechanisms of skin, nerve and muscle regeneration compared [0.03%]
皮肤、神经和肌肉再生的细胞机制比较：修复与重建
Dario Coletti,Laura Teodori,Zhenlin Lin et al.
Dario Coletti et al.
In tissues characterized by a high turnover or following acute injury, regeneration replaces damaged cells and is involved in adaptation to external cues, leading to homeostasis of many tissues during adult life. An understanding of the mec...