Impact of the ATM/Chk2 pathway and cell cycle phase on radiation-induced senescence in A549 human lung cancer cells [0.03%]
ATM/Chk2通路及细胞周期阶段对A549人肺癌细胞辐射诱导衰老的影响
Kota Sato,Hironori Yoshino,Yoshiaki Sato et al.
Kota Sato et al.
Cell senescence is a state of stable proliferation arrest characterized by morphological changes and high senescence-associated β-galactosidase (SA-β-gal) activity. Inducing senescence in cancer cells is beneficial for cancer therapy due ...
Conserved methylation signature accurately predicts heavily irradiated CNS tumour with perplexing histopathology: A case report [0.03%]
保守的甲基化标志准确预测出具有令人困惑组织病理学的重度放射中央神经系统肿瘤：病例报告
Handoko Handoko,Eka Susanto,Renindra Ananda Aman et al.
Handoko Handoko et al.
Diagnosing central nervous system (CNS) tumours post-radiation therapy is often complicated by treatment-induced histological changes. Molecular diagnostics, such as methylation profiling, offer robust tools to aid in accurate tumour classi...
Expression of Oct3/4 isoforms and its association with the risk of relapse in acute lymphoblastic leukemia [0.03%]
OCT3/4各异构体在急性淋巴细胞白血病复发风险中的表达及意义研究
Jorge Organista-Nava,Yazmín Gómez-Gómez,Corayma Yazmín Gómez-Sánchez et al.
Jorge Organista-Nava et al.
Oct3/4 is a transcription factor that maintains the stemness of both embryonic and adult stem cells. The Oct3/4 gene produces three isoforms: namely, Oct3/4A, Oct3/4B and Oct3/4B1. Increased Oct3/4 expression is associated with lower surviv...
Xi Chen,Jin-Zhou Yang,Ling-Yue Kong et al.
Xi Chen et al.
Epilepsy is a frequently occurring complication in patients with gliomas that substantially impairs their quality of life. The onset of epilepsy in patients with gliomas is driven by multiple mechanisms, including tumour-induced compression...
Efficacy of 12-month romosozumab monotherapy or combination with eldecalcitol in patients with osteoporosis with and without chronic kidney disease: A real-world retrospective study [0.03%]
Romosozumab单药或与艾地罗联合治疗慢性肾病患者和非慢性肾病患者的骨质疏松疗效：一项真实世界回顾性研究
Teruya Uchiyama,Koichiro Murata,Toshibumi Kono et al.
Teruya Uchiyama et al.
Evidence regarding the clinical benefits of combination therapy with romosozumab and active vitamin D analogs in the treatment of osteoporosis is lacking. The aim of the present study was to evaluate the outcome of romosozumab (ROMO) as wel...
Syzygium samarangense fruit extract attenuates hyperglycemia in type 2 diabetic rats through modulation of oxidative stress and inflammation [0.03%]
Syzygium samarangense果实提取物通过调节氧化应激和炎症减轻2型糖尿病大鼠的高血糖症状
Kanchana Suksri,Nipaporn Muangchan,Bancha Yingngam et al.
Kanchana Suksri et al.
The global incidence of type 2 diabetes mellitus (T2DM), a chronic metabolic disorder, is on the rise, with persistent hyperglycemia contributing to vascular complications. The present study aimed to assess the preventive effects of Syzygiu...
Comprehensive genomic profiling of Taiwanese triple-negative breast cancer samples with medium- and large-sized sequencing panels: A comparative study implicating treatment allocations [0.03%]
台湾三阴性乳腺癌标本的全面基因组分析：中大型测序panel的比较研究及对治疗分配的启示
Chi-Cheng Huang,Yi-Chen Yeh,Yi-Fang Tsai et al.
Chi-Cheng Huang et al.
Comprehensive genomic profiling (CGP) is a molecular diagnostic tool with increasing use in cancer research and treatment. There are several commercialized CGP assays with variable targeted genes, while the differences between medium- and l...
Impact of weight loss and lifestyle modifications on liver fibrosis in MASLD and MetALD: A cohort study [0.03%]
体重减轻和生活方式改变对MASLD和MetALD患者肝纤维化影响的队列研究
Tatsuki Ichikawa,Satoshi Miuma,Mio Yamashima et al.
Tatsuki Ichikawa et al.
The present study aimed to investigate the impact of weight loss and abstinence and exercise on liver fibrosis in metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatotic liver disease ...
Evaluation of common genetic risk factors for differentiated thyroid cancer in the Thai population [0.03%]
评估泰国人群分化型甲状腺癌常见遗传危险因素的影响
Patra Yeetong,Aunchalee Laipiriyakun,Jiraporn Sriprapaporn et al.
Patra Yeetong et al.
Differentiated thyroid carcinoma (DTC) is the most common endocrine malignancy. This disease includes papillary and follicular thyroid tumors, and accounts for the majority of thyroid cancer cases. Although both genetic and environmental va...
Aortitis after granulocyte-colony stimulating factor administration: A case report [0.03%]
粒细胞集落刺激因子治疗后的主动脉炎一例报告
Shuichi Fujiwara,Hitomi Hara,Naomasa Fukase et al.
Shuichi Fujiwara et al.
Granulocyte-colony stimulating factor (G-CSF) is commonly used to reduce neutropenia-related complications following chemotherapy. It is a glycoprotein that stimulates the production of granulocytes [white blood cells (WBCs) in the bone mar...
Case Reports
Biomedical reports. 2025 Jul 30;23(4):161. DOI:10.3892/br.2025.2039 2025