Association of Murine Double Minute 2 polymorphisms with gastric cancer: A systematic review with meta-analysis [0.03%]
Murine双小体2多态性与胃癌的关联：系统评价和meta分析
Mafalda Timóteo,Ana Tavares,Sara Cruz et al.
Mafalda Timóteo et al.
Gastric cancer (GC) is the 5th most common type of cancer, with the 3rd highest mortality rate worldwide in both sexes. Murine double minute 2 (MDM2) protein is the major negative regulator of p53, and genetic polymorphisms in this gene hav...
Verification of performance of a direct fluorescent assay for cell-free DNA quantification, stability according to pre-analytical storage conditions, and the effect of freeze-thawing [0.03%]
直接荧光测定法检测游离DNA性能验证、样本储存条件对游离DNA稳定性的影响及冻融对游离DNA定量结果影响的研究
Jae-Joon Kim,Kwonoh Park,Yu Ran Han et al.
Jae-Joon Kim et al.
A simple fluorescence-based cell-free DNA (CFD) assay has been previously developed that can directly measure nucleic acids without prior DNA extraction and amplification. However, studies on fluorescence-based CFD are lacking. In particula...
Mechanism of PI3K/Akt‑mediated mitochondrial pathway in obesity‑induced apoptosis (Review) [0.03%]
PI3K/Akt介导的肥胖诱导的线粒体凋亡途径机制(综述)
Obesity is a pervasive global health challenge that substantially reduces the quality of life of millions of individuals and impedes social and economic advancement. Obesity is an independent risk factor that contributes to a range of chron...
Resveratrol ameliorates high‑fat diet‑induced insulin resistance via the DDIT4/mTOR pathway in skeletal muscle [0.03%]
白藜芦醇通过DDIT4/mTOR信号途径改善骨骼肌高脂饮食诱导的胰岛素抵抗
Resveratrol (RSV) is a natural ingredient used in the treatment of diabetes mellitus. However, the antidiabetic mechanism of RSV is not clear. In the present study the antidiabetic mechanism of RSV was investigated using mice with high-fat ...
Elevated PTPN3 expression in type 2 diabetes mellitus: Insights from genetic and experimental analyses [0.03%]
2型糖尿病中PTPN3表达升高：来自遗传学和实验分析的启示
Type 2 diabetes mellitus (T2DM) is associated with chronic hyperglycemia, leading to severe complications, including increased risk of cancer. Protein tyrosine phosphatase non-receptor type 3 (PTPN3) is implicated in both T2DM and cancer pr...
Efficacy and safety of loxoprofen sodium cataplasms in the treatment of osteoarthritis: A randomized, multicenter study [0.03%]
治疗骨关节炎的钠洛索profen膏药的有效性和安全性:随机,多中心研究
The present study aimed to compare the efficacy and safety of loxoprofen sodium cataplasm (LSC) with those of flurbiprofen cataplasm (FPC) in osteoarthritis (OA) treatment. In this multicenter, randomized controlled trial, subjects meeting ...