Effect of the roselle (Hibiscus sabdariffa L.) calyces drink on the physiological parameters of healthy adult subjects [0.03%]
玫瑰茄(Hibiscus sabdariffa L.)泡水对健康成年人生理参数的影响
Ajeng Diantini,Syamsul Rahmat,Annisa Alpiani et al.
Ajeng Diantini et al.
The calyx of roselle (Hibiscus sabdariffa L.) has been the focus of attention of several studies, and although earlier studies on this plant showed it to possess antilipidemic and antidiabetic activities, none of these studies have assessed...
A 5-year evaluation of chemoprophylactic treatment in elementary school children with subclinical leprosy [0.03%]
小学生亚临床性麻风化学预防治疗的五年评价研究
Linda Astari,Nastiti Intan Permata Sari,Kusnartedjo Nanang et al.
Linda Astari et al.
Subclinical leprosy is an infectious disease in which the immune system remains infected with Mycobacterium leprae (M. leprae). The progress of subclinical leprosy to clinical cases within 1 year of infection is 1.5%, with an increase to 6%...
Effect of genotype on the disease course in idiopathic pulmonary fibrosis despite antifibrotic treatment [0.03%]
基因型对接受抗纤维化治疗的特发性肺纤维疾病进程的影响
Martina Sterclova,Amit Kishore,Katerina Sikorova et al.
Martina Sterclova et al.
A genetic predisposition has been identified in 30% of idiopathic pulmonary fibrosis (IPF) cases. Although it is highly probable that the genotype affects the disease susceptibility and course in almost all patients, the specific genotype g...
The role of immunogenic cell death in gastrointestinal cancer immunotherapy (Review) [0.03%]
免疫性细胞死亡在胃肠道癌症免疫治疗中的作用（综述）
Worawat Songjang,Chatchai Nensat,Sutatip Pongcharoen et al.
Worawat Songjang et al.
Modern cancer immunotherapy techniques are aimed at enhancing the responses of the patients' immune systems to fight against the cancer. The main promising strategies include active vaccination of tumor antigens, passive vaccination with an...
lncRNA HIF1A-AS2: A potential oncogene in human cancers (Review) [0.03%]
长链非编码RNA HIF1A-AS2：在人类癌症中的潜在致癌作用（综述）
Yang Liu,Yunyan Zhang,Cha Chen et al.
Yang Liu et al.
Long non-coding RNAs (lncRNAs) are transcripts that are >200 nucleotides, but with no open reading frame. An increasing number of lncRNAs have been identified following the development of second-generation sequencing technologies, and they ...
Autophagy controls programmed death-ligand 1 expression on cancer cells (Review) [0.03%]
自噬调控癌细胞程序性死亡配体1的表达(综述)
Lijuan Gao,Yongshun Chen
Lijuan Gao
Programmed death-ligand 1 (PD-L1) is a transmembrane protein mainly located on cancer cells, including renal cell carcinoma, breast, colorectal, gastric and non-small cell lung cancer. PD-L1 binds to the PD-1 receptor expressed on T lymphoc...
Variant Philadelphia t(X;9;22)(q22?;q34;q11.2) can be successfully treated with second generation tyrosine kinase inhibitors: A case report and literature review [0.03%]
应用二代酪氨酸激酶抑制剂成功治疗变异费城染色体t(X;9;22)(q22?;q34;q11.2)白血病一例及文献复习
Ana Iglesias,Raluca Oancea,Carmen Cotarelo et al.
Ana Iglesias et al.
Chronic myeloid leukemia (CML) is characterized by the reciprocal translocation between chromosomes 9 and 22: t(9;22)(q34;q11). However, 5-10% of patients with CML have complex variant translocations involving at least a third chromosome; o...
Case Reports
Biomedical reports. 2021 Oct;15(4):83. DOI:10.3892/br.2021.1459 2021
Droplet-based digital PCR for non-invasive prenatal genetic diagnosis of α and β-thalassemia [0.03%]
基于液滴的数字PCR在无创性产前α和β地中海贫血基因诊断中的应用
Kritchakorn Sawakwongpra,Kulvadee Tangmansakulchai,Wasinee Ngonsawan et al.
Kritchakorn Sawakwongpra et al.
Non-invasive prenatal diagnosis (NIPD) of isolated cell-free DNA from maternal plasma has been applied to detect monogenic diseases in the fetus. Droplet digital PCR (ddPCR) is a sensitive and quantitative technique for NIPD. In the present...
Tripterygium wilfordii derivative LLDT-8 targets CD2 in the treatment of rheumatoid arthritis [0.03%]
雷公藤内酯LLDT-8通过作用于CD2治疗类风湿关节炎
Yuan Li,Wufang Qi,Lei Yan et al.
Yuan Li et al.
Rheumatoid arthritis (RA), a chronic inflammatory synovitis systemic disease, can lead to joint deformities, loss of function and even death. The pathogenesis of RA may be related to genetics, infection and/or sex hormones; however, detaile...
Association between polymorphisms of genes involved in the Renin-Angiotensin-Aldosterone System and the adaptive morphological and functional responses to essential hypertension [0.03%]
肾素血管紧张素醛固酮系统相关基因多态性与原发性高血压形态及功能代偿反应的关系研究
Oana Mocan,Dan Rădulescu,Elena Buzdugan et al.
Oana Mocan et al.
Hypertensive cardiac remodeling is illustrated by increased left ventricular (LV) mass index values and/or relative wall thickness (RWT) values >0.42, and functionally by isolated alteration of LV diastole (abnormal relaxation). The aim of ...